CAS 1193779-48-4

1-(3,5-Dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone

Prodotto controllato

CAS: 1193779-48-4

Applications 1-(3,5-Dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone is an intermediate in the synthesis of 5-Chloro Bupropion Fumarate (C364765). A 5-chloro substitued analogue of Bupropion (B689625) used in the preparation of compounds for indirect dopamine agonist pharmacotherapy for treating cocaine, methamphetamine, nicotine, and other drugs of abuse addiction.
References Carroll, F.I. et al.: J. Med. Chem., 52, 6768 (2009)

Formula: C₁₃H₁₇Cl₂NO

Colore e forma: Neat

Peso molecolare: 274.19

Ref: TR-D475123

2-(tert-Butylamino)-3’,5’-dichloropropiophenone-d9 Hydrochloride

Prodotto controllato

CAS: 1193779-48-4, 1346603-00-6

Applications A labelled impurity of Bupropion (B689625). It has inhibitory effect on monoamine uptake and antagonizes the effects of human α3β4*, α4β2, α4β4, and α1* nicotinic acetylcholine receptors (nAChRs)
References Carroll, F.I. et al.: J. Med. Chem., 53, 2204 (2010);

Formula: C₁₃D₉H₈Cl₂NO·HCl

Colore e forma: Neat

Peso molecolare: 319.7

Ref: TR-B690692