CAS 119478-56-7

Meropenem triidrato

Descrizione:

Meropenem triidrato è un antibiotico ad ampio spettro appartenente alla classe dei carbapenemi, utilizzato principalmente per trattare infezioni batteriche gravi. È caratterizzato dalla sua capacità di inibire la sintesi della parete cellulare batterica, rendendolo efficace contro un'ampia gamma di batteri Gram-positivi e Gram-negativi, inclusi quelli resistenti ad altri antibiotici. La forma di trihidrato indica che il composto contiene tre molecole d'acqua per molecola di meropenem, il che può influenzare la sua solubilità e stabilità. Il meropenem viene tipicamente somministrato per iniezione endovenosa a causa della sua scarsa biodisponibilità orale. È noto per le sue favorevoli proprietà farmacocinetiche, tra cui una vita media relativamente lunga e una buona penetrazione nei tessuti. Gli effetti collaterali comuni possono includere disturbi gastrointestinali, mal di testa e potenziali reazioni allergiche. Come con altri antibiotici, l'emergere di resistenza è una preoccupazione, richiedendo un uso attento e l'adesione ai regimi prescritti. In generale, Meropenem triidrato è un'opzione critica nel trattamento di infezioni gravi, particolarmente in contesti ospedalieri.

Formula: C₁₇H₂₅N₃O₅S

InChI: InChI=1/C17H25N3O5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4/h7-12,18,21H,5-6H2,1-4H3,(H,24,25)/t7-,8+,9-,10-,11-,12-/m0/s1

InChI key: InChIKey=CTUAQTBUVLKNDJ-OBZXMJSBSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@@]([C@@H](C)O)(C2=O)[H])([C@@H](C)C1S[C@H]3C[C@@H](C(N(C)C)=O)NC3)[H].O

Sinonimi:

• (4R,5S,6S)-3-[[(3S,5S)-5-(Dimethylcarbamoyl)-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid trihydrate
• (4R,5S,6S)-3-[[(3S,5S)-5-(Dimethylcarbamoyl)pyrrolidin-3-yl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• (4R,5S,6S)-3-{[(2S,5S)-5-(dimethylcarbamoyl)pyrrolidin-2-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid trihydrate
• (4S,5R,6R)-3-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, hydrate (1:3), (4R,5S,6S)-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, trihydrate, (4R,5S,6S)-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, trihydrate, [4R-[3(3S*,5S*),4α,5β,6β(R*)]]-
• Meropenem (with carbonate)
• Meropenem trihydrate
• Meropenem
• 3-[[5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3,2,0]hept-2-ene-2-carboxylic acid trihydrate
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, trihydrate, [4R-[3(3S*,5S*),4a,5b,6b(R*)]]-(9CI)
• MEROPENEM WITH SODIUM CARBONATE
• MEROPENEM
• MEROPENEMTRIHYDRATE(3-[[5-[(DIMETHYLAMINO)CARBONYL]-3-PYRROLIDINYL]THIO]-6-(1-HYDROXYETHYL)-4-METHYL-7-OXO-1-AZABICYCLO[3,2,0]HEPT-2-ENE-2-CARBOXYLICACIDTRIHYDRATE)

Meropenem Trihydrate

CAS: 119478-56-7, 96036-03-2

Formula: C₁₇H₂₅N₃O₅S·3H₂O

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 437.51

Ref: 3B-M2279

Meropenem trihydrate, 98-101%

CAS: 119478-56-7

A broad spectrum antibiotic targeting a wide range of bacteria

Formula: C₁₇H₃₁N₃O₈S

Purezza: 98-101%

Colore e forma: Powder or crystals or crystalline powder, White to pale yellow

Peso molecolare: 437.51

Ref: 02-J66446

MEROPENEM TRIHYDRATE CRS

CAS: 119478-56-7

MEROPENEM TRIHYDRATE CRS

Formula: C₁₇H₂₅N₃O₅S

Colore e forma: Added Modified

Peso molecolare: 383.4625

Ref: 41-Y0001252

Meropenem

CAS: 119478-56-7

Antibiotics nesoi

Formula: C₁₇H₂₅N₃O₅S·3H₂O

Colore e forma: White Light Yellow Powder

Peso molecolare: 437.51

Ref: 45-1392454

(4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid trihydrate

CAS: 119478-56-7

Formula: C₁₇H₃₁N₃O₈S

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 437.5083

Ref: IN-DA000IV3

Meropenem trihydrate

CAS: 119478-56-7

Meropenem trihydrate (SM 7338 trihydrate) with broad-spectrum antibacterial activity,is a carbapenem antibiotic.

Formula: C₁₇H₃₁N₃O₈S

Purezza: 99.80%

Colore e forma: Solid

Peso molecolare: 437.51

Ref: TM-T12004

Meropenem trihydrate

CAS: 119478-56-7

Formula: C₁₇H₂₅N₃O₅S·3H₂O

Purezza: ≥ 98.0% (anhydrous basis)

Colore e forma: White, off-white or faint beige crystalline powder

Peso molecolare: 437.51

Ref: 7W-GP7412

Meropenem trihydrate, USP grade

CAS: 119478-56-7

Formula: C₁₇H₂₅N₃O₅S·3H₂O

Purezza: ≤ 0.1% (anhydrous basis)

Colore e forma: White, off-white or faint beige crystalline powder

Peso molecolare: 437.51

Ref: 7W-GP9211

Meropenem trihydrate

CAS: 119478-56-7

Meropenem trihydrate

Purezza: ≥98%

Peso molecolare: 437.51g/mol

Ref: 54-BUP15105

Meropenem trihydrate

Prodotto controllato

CAS: 119478-56-7

Formula: C₁₇H₂₅N₃O₅SH₂O

Colore e forma: Neat

Peso molecolare: 437.51

Ref: 04-C14906000

Meropenem Trihydrate

CAS: 119478-56-7

Colore e forma: Neat

Ref: 86-MM1327.00

Meropenem RS

CAS: 119478-56-7

Colore e forma: White To Light Yellow Solid Crystalline Powder

Ref: 2K-7000960021

Meropenem Trihydrate

Prodotto controllato

CAS: 119478-56-7

Applications Meropenem Trihydrate is a carbapenem antibiotic with wide spectrum of antibacterial.
References Hickey, M.B., et al.: J. Pharma. Sci., 96, 1090 (2007); Condie, C.K., et al.: Am. J. Health. System. Pharma., 65, 454 (2008);

Formula: C₁₇H₂₅N₃O₅S·3H₂O

Colore e forma: Light Yellow

Peso molecolare: 437.51

Ref: TR-M225640

Meropenem Trihydrate

CAS: 119478-56-7

Formula: C₁₇H₂₅N₃O₅S(H₂O)

Peso molecolare: 383.5 : 3(18.0)

Ref: ST-EA-CP-M30000

Meropenem trihydrate

CAS: 119478-56-7

Inhibitor of cell-wall synthesis; carbapenem class

Formula: C₁₇H₂₅N₃O₅S·3H₂O

Purezza: Min. 95 Area-%

Colore e forma: Powder

Peso molecolare: 437.51 g/mol

Ref: 3D-AM16380

Meropenem trihydrate, Antibiotic for Culture Media Use Only

CAS: 119478-56-7

Meropenem trihydrate has broad spectrum activity against Gram-positive and Gram-negative bacteria, as well as, some mycoplasma species. It inhibits cell wall synthesis by binding to bacterial penicillin-binding proteins (PBP), which impairs cell wall integrity, induces the formation of reactive oxygen species, and inhibits macromolecular synthesis in bacteria. It can be used to prevent bacterial growth after being exposed to meropenem through fluorescence imaging of human blood plasma. Meropenem trihydrate research studies showed a reduction of the allergen levels in patients with respiratory allergies or asthma, specifically dust mites, cockroaches, animal dander, pollen grains, etc. by inhibit allergen-induced sensitization of mast cells.

Formula: C₁₇H₃₁N₃O₈S

Purezza: Min. 98.0 Area-%

Peso molecolare: 437.51 g/mol

Ref: 3D-M-2780

Meropenem trihydrate

CAS: 119478-56-7

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 437.51

Ref: 10-F792074