CAS 120202-66-6
:Solfato di idrogeno di clopidogrel
Descrizione:
Solfato di idrogeno di clopidogrel è un composto farmaceutico utilizzato principalmente come agente antipiastrinico per prevenire la formazione di coaguli di sangue in pazienti a rischio di eventi cardiovascolari. È un pro-farmaco che richiede attivazione metabolica nel fegato per esercitare i suoi effetti terapeutici. La sostanza è caratterizzata dalla sua capacità di inibire irreversibilmente il recettore P2Y12 sulle piastrine, riducendo così l'aggregazione piastrinica. Solfato di idrogeno di clopidogrel viene tipicamente somministrato per via orale ed è noto per la sua relativamente alta biodisponibilità e lunga emivita, consentendo una somministrazione una volta al giorno. Il composto è solubile in acqua e presenta stabilità in condizioni normali di stoccaggio, sebbene debba essere protetto dalla luce e dall'umidità. Gli effetti collaterali comuni possono includere complicazioni emorragiche, disturbi gastrointestinali e reazioni di ipersensibilità. A causa del suo meccanismo d'azione, è spesso prescritto in concomitanza con altre terapie antipiastriniche o anticoagulanti, in particolare in pazienti con una storia di infarto miocardico o ictus. Il monitoraggio dell'efficacia e degli effetti avversi è essenziale durante il trattamento.
Formula:C15H16ClNO6S2
InChI:InChI=1/C15H14ClNO2S.H2O4S/c16-12-4-2-1-3-11(12)14(15(18)19)17-7-5-13-10(9-17)6-8-20-13;1-5(2,3)4/h1-4,6,8,14H,5,7,9H2,(H,18,19);(H2,1,2,3,4)/t14-;/m0./s1
InChI key:InChIKey=FDEODCTUSIWGLK-RSAXXLAASA-N
SMILES:[C@H](C(OC)=O)(N1CC2=C(CC1)SC=C2)C3=C(Cl)C=CC=C3.S(=O)(=O)(O)O
Sinonimi:- (+)-(S)-5-[(2-Chlorophenyl)(methoxycarbonyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]-pyridin-5-ium hydrogen sulfate]
- (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoic acid sulfate (1:1)
- (S)-(+)-Clopidogrel hydrogen sulfate
- (S)-(+)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate bisulfate
- (S)-(+)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogen sulfate
- Areplex
- Clopidix
- Clopidogerl Bisulfate
- Clopidogrel Bisulfate
- Clopidogrel Bisulfate I
- Clopidogrel Bisulfate II
- Clopidogrel Bisulfate, FormI/FormII
- Clopidogrel Hydrogen Sulphate
- Clopidogrel Hydrogensulfate
- Clopidogrel Sulphate
- Clopidogrel bisulphate
- Clopidogrel bisulphate Ⅰ/Ⅱ
- Clopidogrel hemisulfate
- Clopidogrel sulfate
- Iscover
- Methyl (+)-(S)-A-(2-Chlorophenyl)-6,7-Dihydrothieno[3,2-C]Pyridine-5(4H)Acetate, Hydrogen Sulfate Salt
- Methyl (S)-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)(2-chlorophenyl)ethanoate hydrogen sulfate
- Myogrel
- Plavitor
- Plavix
- Sr 25990C
- Stroka
- Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (S)-, sulfate (1:1)
- Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (αS)-, sulfate (1:1)
- Trombex
- Zyllt
- Clopidogrel hydrogen sulfate
- (S)-alpha-(2-Chlorophenyl)-6,7-dihydrothieno[3.2-c]pyridine-5(4H)-aceticacidmethylesterhydrogensulfate
- Clopidogrelhydrogenesulfate
- Clopidogrel (Hydrogen)
- (2-Chlorophenyl)-6,7–dihydrothieno[3,2-C]pyridine-5-(4H)-acetic acid methyl ester sulfate
- d-Clopidogrel
- Vedi altri sinonimi
Ordinare per
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17 prodotti.
(S)-(+)-Clopidogrel Sulfate
CAS:Formula:C16H16ClNO2S·H2SO4Purezza:>98.0%(HPLC)(N)Colore e forma:White to Almost white powder to crystalPeso molecolare:419.89Clopidogrel hydrogen sulfate
CAS:Clopidogrel hydrogen sulfateFormula:C16H18ClNO6S2Purezza:99.4%Colore e forma:Off-WhitePeso molecolare:419.02641CLOPIDOGREL HYDROGEN SULFATE CRS
CAS:CLOPIDOGREL HYDROGEN SULFATE CRSFormula:C16H18ClNO6S2Colore e forma:White. Whitish. Powder.Peso molecolare:419.9002Clopidogrel Bisulfate
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C16H16ClNO2S·H2SO4Colore e forma:White Off-White PowderPeso molecolare:321.05903Thieno[3,2-c]pyridine-5(4H)-acetic acid,a-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (aS)-, sulfate (1:1)
CAS:Formula:C16H18ClNO6S2Purezza:98%Colore e forma:SolidPeso molecolare:419.9002Clopidogrel hydrogen sulfate
CAS:<p>Clopidogrel hydrogen sulfate is a selective P2Y12 receptor blocker that inhibits platelet adhesion and aggregation.</p>Formula:C16H16ClNO2S·H2SO4Purezza:99.57% - 99.79%Colore e forma:SolidPeso molecolare:419.9Clopidogrel Sulfate
CAS:Formula:C16H16ClNO2S·H2SO4Colore e forma:White To Off-White SolidPeso molecolare:321.82 98.07(S)-(+)-Clopidogrel hydrogen sulfate
CAS:Formula:C16H16ClNO2S·H2SO4Purezza:≥ 98.0%Colore e forma:White to off-white powderPeso molecolare:419.90S-(+)-Clopidogrel Hydrogen Sulfate
CAS:<p>Applications Used as an antithrombotic.<br>References Mills, D.C.B., et al.: Arterioscler. Thromb., 12, 430 (1992), Feuerstein, G., et al.: Exp. Opin. Invest. Drugs, 4, 425 (1995)<br></p>Formula:C16H16ClNO2S·H2O4SColore e forma:Off-WhitePeso molecolare:419.90S-(+)-Clopidogrel hydrogen sulfate
CAS:<p>Clopidogrel is a potent inhibitor of the platelet aggregation. It reduces blood clotting by inhibiting the ADP receptor on the surface of platelets, thereby inhibiting the aggregation and adhesion of platelets. Clopidogrel has been shown to be effective in preventing thrombosis, myocardial infarction (heart attack), and stroke. Clopidogrel inhibits the activity of cytochrome P450 3A4 (CYP3A4) and p2Y 12 receptors. Clopidogrel has been shown to have synergic effects with nonsteroidal anti-inflammatory drugs (NSAIDs). The polymorphic nature of Clopidogrel can be monitored using a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for quantification in biological samples such as human serum and plasma.</p>Formula:C16H18ClNO6S2Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:419.9 g/molS-(+)-Clopidogrel hydrogen sulfate - Bio-X ™
CAS:<p>Clopidogrel is a potent inhibitor of the platelet aggregation. It reduces blood clotting by inhibiting the ADP receptor on the surface of platelets, thereby inhibiting the aggregation and adhesion of platelets. Clopidogrel has been shown to be effective in preventing thrombosis, myocardial infarction (heart attack), and stroke. Clopidogrel inhibits the activity of cytochrome P450 3A4 (CYP3A4) and p2Y 12 receptors. Clopidogrel has been shown to have synergic effects with nonsteroidal anti-inflammatory drugs (NSAIDs). The polymorphic nature of Clopidogrel can be monitored using a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for quantification in biological samples such as human serum and plasma.</p>Formula:C16H16ClNO2S•H2SO4Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:419.9 g/mol
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