CAS 120796-97-6

grande endotelina 38 umana

Descrizione:

Il big endotelina-1 (spesso riferito come big endotelina-38 nel contesto della biologia umana) è un peptide precursore coinvolto nella regolazione del tono vascolare e della pressione sanguigna. Fa parte della famiglia delle endotelina, che include diverse isoforme prodotte dalle cellule endoteliali. La sostanza è caratterizzata dalla sua struttura molecolare relativamente grande, che viene scissa per formare peptidi attivi di endotelina, specificamente endotelina-1, -2 e -3. Questi peptidi sono potenti vasocostrittori e svolgono un ruolo cruciale in vari processi fisiologici, inclusa la funzione cardiovascolare e l'equilibrio dei fluidi. Il big endotelina-1 viene tipicamente rilasciato in risposta a vari stimoli, inclusi ipossia e infiammazione, e i suoi livelli possono essere indicativi di alcune condizioni patologiche, come l'insufficienza cardiaca e l'ipertensione polmonare. Il numero CAS 120796-97-6 identifica specificamente questo peptide precursore, che è importante per la ricerca e le applicazioni cliniche nella comprensione della salute cardiovascolare e dei meccanismi di malattia.

Formula: C₁₈₉H₂₈₂N₄₈O₅₆S₅

Big Endothelin-1 (human)

CAS: 120796-97-6

Human Big ET-1 comprises residues 53-90 of the endothelin precursor (preproendothelin). Compared to the mature endothelin-1 (hET-1), the peptide show less vasoconstrictor activity in vitro, but similar pressor effects in vivo. Former CAS-number 121014-53-7.

Formula: C₁₈₉H₂₈₂N₄₈O₅₆S₅

Purezza: 94.0%

Colore e forma: White Powder

Peso molecolare: 4282.94

Ref: 01-4014579

Big Endothelin 1 (human)

CAS: 120796-97-6

Big Endothelin 1 (human)

Ref: 54-BIBA1032

Big Endothelin-1 (Human, 1-38)

CAS: 120796-97-6

This product has disulfide bonds between Cys1-Cys15 and Cys3-Cys11 and is available as a 0.5mg vial. Big Endothelin-1 (Human, 1-38) is a peptide that is a member of the endothelin family and is part of the 39 amino acids of Big Endothelin-1 which is a precursor of Endothelin-1 (ET-1). ET-1 exhibits vasoconstrictive properties and is an activator of endothelin G-protein coupled receptors. Furthermore ET-1 is produced when inflammation, vascular stress or hypoxia occurs. In vivo Big Endothelin-1 has a greater half life compared to ET-1 and therefore makes it useful to study secretory activity in the endothelial system.
Overall Big Endothelin-1 (Human, 1-38) can be used as a research tool for studying protein interactions, receptor activation and function, and ligand binding. This peptide is also used in pharmacology to study the effects of therapeutic agents on receptor activity and expression.

Formula: C₁₈₉H₂₈₂N₄₈O₅₆S₅

Purezza: Min. 95%

Peso molecolare: 4,282.9 g/mol

Ref: 3D-PED-4208-V

Big Endothelin-1 (human)

CAS: 120796-97-6

Please enquire for more information about Big Endothelin-1 (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₈₉H₂₈₂N₄₈O₅₆S₅

Purezza: Min. 95%

Peso molecolare: 4,282.88 g/mol

Ref: 3D-FB110372

Big Endothelin-1 (Human, 1-38)

CAS: 120796-97-6

This product has disulfide bonds between Cys1-Cys15 and Cys3-Cys11 and is available as a 0.1mg vial. Big Endothelin-1 (Human, 1-38) is part of the full lengthed 29 amino acid peptide Big Endothlin-1 which is a precursor peptide of the vasoconstrictorEndothelin-1 (ET-1). ET-1 exhibits vasoconstrictive properties and is an activator of endothelin G-protein coupled receptors. Furthermore ET-1 is produced when inflammation, vascular stress or hypoxia occurs. In vivo Big Endothelin-1 has a greater half life compared to ET-1 and therefore makes it useful to study secretory activity in the endothelial system.
Overall Big Endothelin-1 (Human, 1-38) can be used as a research tool for studying protein interactions, receptor activation and function, and ligand binding. This peptide is also used in pharmacology to study the effects of therapeutic agents on receptor activity and expression.

Formula: C₁₈₉H₂₈₂N₄₈O₅₆S₅

Purezza: Min. 95%

Peso molecolare: 4,282.9 g/mol

Ref: 3D-PED-4208-S