CAS 1210344-57-2

Ertugliflozin

Descrizione:

Ertugliflozin è un farmaco utilizzato principalmente nella gestione del diabete mellito di tipo 2. Appartiene alla classe di farmaci noti come inibitori del cotrasportatore sodio-glucosio 2 (SGLT2), che funzionano prevenendo il riassorbimento della glucosio nei reni, promuovendo così la sua escrezione nelle urine e abbassando i livelli di glucosio nel sangue. La formula chimica di Ertugliflozin riflette la sua struttura, che include un gruppo glucosio legato a un sistema di anello aromatico specifico. Questo composto è caratterizzato dalla sua capacità di migliorare il controllo glicemico e può anche contribuire alla perdita di peso e ai benefici cardiovascolari nei pazienti diabetici. Inoltre, Ertugliflozin è stato studiato per i suoi potenziali effetti sulla funzione renale. Gli effetti collaterali comuni possono includere infezioni del tratto urinario e infezioni micotiche genitali, che sono associate a un aumento della glucosio nelle urine. Come con qualsiasi farmaco, è essenziale che i pazienti consultino professionisti sanitari per consigli personalizzati e monitoraggio durante l'uso di Ertugliflozin.

Formula: C₂₂H₂₅ClO₇

InChI: InChI=1S/C22H25ClO7/c1-2-28-16-6-3-13(4-7-16)9-14-10-15(5-8-17(14)23)22-20(27)18(25)19(26)21(11-24,30-22)12-29-22/h3-8,10,18-20,24-27H,2,9,11-12H2,1H3/t18-,19-,20+,21-,22-/m0/s1

InChI key: InChIKey=MCIACXAZCBVDEE-CUUWFGFTSA-N

SMILES: O[C@H]1[C@@]2(O[C@@](CO)(CO2)[C@@H](O)[C@@H]1O)C3=CC(CC4=CC=C(OCC)C=C4)=C(Cl)C=C3

Sinonimi:

• (1S,2S,3S,4R,5S)-5-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol
• 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-beta-L-idopyranose
• 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-<span class="text-smallcaps">L</span>-idopyranose
• Cc-212
• Mk 8835
• Pf 04971729-00
• Pf-04971729
• β-<span class="text-smallcaps">L</span>-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-
• Ertugliflozin
• β-L-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-
• 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-L-idopyranose
• PF04971729;PF 04971729 (ERTUGLIFLOZIN)
• Ertugliflozin Base
• 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-beta-L-idopyranose PF-04971729(Ertugliflozin)
• PF-04971729/Ertugliflozin
• (1S,2S,3S,4R,5S)-(2,3,4-TRIS-BENZYLOXY-5-(4-CHLORO-3-(4-ETHOXY-BENZYL)-PHENYL)-68-DIOXA-BICYCLO(3.2.1)OCT-1-YL)-METHANOL
• Ertugliflozin, >=98%
• (1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol
• Ertugliflozin/PF-04971729
• PF-04971729 USP/EP/BP
• CS-186
• ERTUGLIFLOZIN;PF04971729;PF 04971729
• Ertugliflozin : PF 04971729-00
• Leuco methylthioninium
• Ertugliflozin MK-8835

1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-L-idopyranose

CAS: 1210344-57-2

Formula: C₂₂H₂₅ClO₇

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 436.8827

Ref: IN-DA003AC5

(1S,2S,3S,4R,5S)-5-(4-Chloro-3-(4-Ethoxybenzyl)Phenyl)-1-(Hydroxymethyl)-6,8-Dioxabicyclo[3.2.1]Octane-2,3,4-Triol

CAS: 1210344-57-2

(1S,2S,3S,4R,5S)-5-(4-Chloro-3-(4-Ethoxybenzyl)Phenyl)-1-(Hydroxymethyl)-6,8-Dioxabicyclo[3.2.1]Octane-2,3,4-Triol

Purezza: 98%

Peso molecolare: 436.88g/mol

Ref: 54-OR1026211

Ertugliflozin

CAS: 1210344-57-2

Ertugliflozin

Purezza: ≥98%

Peso molecolare: 436.88g/mol

Ref: 54-BUP15433

Ertugliflozin

CAS: 1210344-57-2

Formula: C₂₂H₂₅ClO₇

Colore e forma: White To Off-White Solid

Peso molecolare: 436.89

Ref: 4Z-E-090001

Ertugliflozin

CAS: 1210344-57-2

PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).

Formula: C₂₂H₂₅ClO₇

Purezza: 99.89% - 99.96%

Colore e forma: Solid

Peso molecolare: 436.88

Ref: TM-T4999

Ertugliflozin

Prodotto controllato

CAS: 1210344-57-2

Formula: C₂₂H₂₅ClO₇

Colore e forma: Neat

Peso molecolare: 436.88

Ref: TR-E635090

Ertugliflozin (PF 04971729)

CAS: 1210344-57-2

Ertugliflozin is a novel, selective, and potent inhibitor of SGLT2. It is being developed for the treatment of type 2 diabetes and associated conditions such as hypertension, dyslipidemia and cardiovascular complications. Ertugliflozin selectively inhibits the renal glucose transporter SGLT2 to reduce urinary glucose excretion. In clinical trials ertugliflozin has been shown to significantly lower HbA1c levels in patients with type 2 diabetes mellitus. The drug was well tolerated in clinical trials with no clinically relevant adverse events observed. This agent has also been shown to decrease blood pressure in patients with type 2 diabetes mellitus and normotensive subjects.

Formula: C₂₂H₂₅ClO₇

Purezza: Min. 96 Area-%

Colore e forma: White Off-White Powder

Peso molecolare: 436.88 g/mol

Ref: 3D-FE137670