CAS 1218-34-4

Acetil-L-triptofano

Descrizione:

Acetil-L-triptofano è un derivato dell'aminoacido triptofano, caratterizzato dall'aggiunta di un gruppo acetile al suo atomo di azoto. Questa modifica migliora la sua solubilità e biodisponibilità rispetto al suo composto originale. La sostanza è tipicamente una polvere cristallina bianca o bianco sporco ed è solubile in acqua e solventi organici, rendendola utile in varie applicazioni biochimiche. Acetil-L-triptofano è noto per il suo potenziale ruolo nella sintesi dei neurotrasmettitori, in particolare della serotonina, e può influenzare la regolazione dell'umore e del sonno. Viene spesso studiato per i suoi effetti sulla funzione cognitiva e come integratore alimentare. Inoltre, può presentare proprietà antiossidanti ed è stato indagato per le sue potenziali applicazioni terapeutiche in condizioni come depressione e ansia. Come per molti derivati degli aminoacidi, è importante considerare il suo profilo di sicurezza e dosaggio quando utilizzato in integratori o ricerche. In generale, Acetil-L-triptofano funge da composto importante sia in contesti nutrizionali che farmaceutici.

Formula: C₁₃H₁₄N₂O₃

InChI: InChI=1S/C13H14N2O3/c1-8(16)15-12(13(17)18)6-9-7-14-11-5-3-2-4-10(9)11/h2-5,7,12,14H,6H2,1H3,(H,15,16)(H,17,18)/t12-/m0/s1

InChI key: InChIKey=DZTHIGRZJZPRDV-LBPRGKRZSA-N

SMILES: C([C@H](NC(C)=O)C(O)=O)C=1C=2C(NC1)=CC=CC2

Sinonimi:

• (2S)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid
• (S)-N-Acetyltryptophan
• <span class="text-smallcaps">L</span>-N-Acetyltryptophan
• <span class="text-smallcaps">L</span>-Tryptophan, N-acetyl-
• Ac-L-Trp-OH
• Acetyl-<span class="text-smallcaps">L</span>-tryptophan
• Acetyltryptophan
• N-Acetyl-<span class="text-smallcaps">L</span>-tryptophan
• N-Acetyl-L-Tryptophan
• N-acetyltryptophan
• N-α-Acetyl-L-Tryptophan
• NSC 90726
• Tryptophan, N-acetyl-, <span class="text-smallcaps">L</span>-
• L-Tryptophan, N-acetyl-
• Acetyl-L-tryptophan
• Tryptophan, N-acetyl-, L-

N-Acetyl-L-tryptophan

CAS: 1218-34-4

Formula: C₁₃H₁₄N₂O₃

Purezza: >98.0%(HPLC)

Colore e forma: White to Light yellow to Light red powder to crystal

Peso molecolare: 246.27

Ref: 3B-A0121

N-Acetyl-L-tryptophan, 99%

CAS: 1218-34-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₃H₁₄N₂O₃

Purezza: 99%

Colore e forma: White to off-white powder

Peso molecolare: 246.27

Ref: 02-J64096

Ac-Trp-OH

CAS: 1218-34-4

The NK1 receptor antagonist Ac-Trp (L-NAT) inhibits the secretion of substance P and IL-1β. L-NAT reduced dyskinesia in a hemi-parkinsonian rodent model.

Formula: C₁₃H₁₄N₂O₃

Purezza: > 99%

Colore e forma: Whitish Powder

Peso molecolare: 246.27

Ref: 01-4003876

N-ACETYLTRYPTOPHAN CRS

CAS: 1218-34-4

N-ACETYLTRYPTOPHAN CRS

Formula: C₁₃H₁₄N₂O₃

Peso molecolare: 246.2619

Ref: 41-A0208000

Tryptophan Related Compound B (2-Acetamido-3-(1H-indol-3-yl)propanoic acid)

CAS: 1218-34-4

Aromatic or modified aromatic heterocyclic compounds withnitrogen hetero-atom(s) only nesoi

Formula: C₁₃H₁₄N₂O₃

Colore e forma: White Off-White Colorless Crystalline Powder Crystals

Peso molecolare: 246.10044

Ref: 45-1700523

L-Tryptophan, N-acetyl-

CAS: 1218-34-4

Formula: C₁₃H₁₄N₂O₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 246.2619

Ref: IN-DA001627

N-Acetyl-L-tryptophan

CAS: 1218-34-4

N-Acetyl-L-tryptophan

Purezza: ≥98%

Peso molecolare: 246.26g/mol

Ref: 54-BUP19215

N-Acetyl-L-tryptophan

CAS: 1218-34-4

Formula: C₁₃H₁₄N₂O₃

Purezza: ≥ 98.5%

Colore e forma: White to almost white powder

Peso molecolare: 246.30

Ref: 7W-GM7304

N-Acetyltryptophan

Prodotto controllato

CAS: 1218-34-4

Formula: C₁₃H₁₄N₂O₃

Colore e forma: Neat

Peso molecolare: 246.26

Ref: 86-MM0172.13

N-Acetyl-L-tryptophan

CAS: 1218-34-4

N-Acetyl-L-tryptophan

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 246.26g/mol

Ref: 54-BIA1792

N-Acetyl-L-tryptophan

CAS: 1218-34-4

N-Acetyl-L-tryptophan (N-acetyltryptophan) is an inhibitor of neurokinin 1 receptor (NK1-receptor, NK1R).

Formula: C₁₃H₁₄N₂O₃

Purezza: 99.93%

Colore e forma: Solid

Peso molecolare: 246.26

Ref: TM-T8789

Tryptophan USP Related Compound B (N-Acetyl-L-Tryptophan)

CAS: 1218-34-4

Formula: C₁₃H₁₄N₂O₃

Peso molecolare: 246.27

Ref: 4Z-T-2019

N-Acetyl-L-Tryptophan

Prodotto controllato

CAS: 1218-34-4

Applications N-Acetyl-L-Tryptophan, is a derivative of L-Tryptophan (T947210), that can be used as competitive inhibitor to identify and characterize tryptophanases. It can also be used as an NK1 tachykinin receptor antagonist, that may help to develop a novel therapeutic intervention for the treatment of reperfusion injury in acute ischemic stroke.
References Turner, R. J., et al.: Neuroscience, 220, 1 (2012);

Formula: C₁₃H₁₄N₂O₃

Colore e forma: White To Off-White

Peso molecolare: 246.26

Ref: TR-A168730

N-Acetyl-L-tryptophan

CAS: 1218-34-4

N-Acetyl-L-tryptophan is a neuroprotective agent that binds to the group p2 receptor for neurokinin-1 (NK-1) and inhibits the apoptosis pathway. It is used in the treatment of Parkinson's disease, Alzheimer's disease, and Huntington's disease. N-Acetyl-L-tryptophan has been shown to inhibit inflammatory lesions in rats with experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis. This drug also interacts with toll-like receptor 4 (TLR4), which activates downstream signaling cascades involving NFκB, MAP kinase, and JAK/STAT pathways. The molecular docking analysis revealed that N-acetyl tryptophan binds to specific sites on TLR4 and prevents its activation by preventing binding of LPS.

Formula: C₁₃H₁₄N₂O₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 246.26 g/mol

Ref: 3D-FA37435

N-Acetyl-L-Tryptophan extrapure, 99%

CAS: 1218-34-4

Formula: C₁₃H₁₄N₂O₃

Purezza: min. 99%

Colore e forma: Off - white to pale brown, Powder, Clear

Peso molecolare: 246.3

Ref: SR-11644

N-Acetyl-L-Tryptophan ExiPlus, Multi-Compendial, 99%

CAS: 1218-34-4

Formula: C₁₃H₁₄N₂O₃

Purezza: min. 99%

Colore e forma: Off white to pale brown, Powder, Clear

Peso molecolare: 246.3

Ref: SR-48861

Ac-Trp-OH

CAS: 1218-34-4

M03025 - Ac-Trp-OH

Formula: C₁₃H₁₄N₂O₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 246.266

Ref: 10-M03025

Tryptophan USP Related Compound B

CAS: 1218-34-4

Formula: C₁₃H₁₄N₂O₃

Peso molecolare: 246.27

Ref: ST-EA-CP-T90020