CAS 1219803-95-8

Doxazosin-d8 HCl

CAS: 1219803-95-8

Formula: C₂₃H₁₇D₈N₅O₅·HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 459.53 36.46

Ref: 4Z-D-141

(+/-)-Doxazosin-d8 HCl(piperazine-d8)

CAS: 1219803-95-8, 70918-01-3

Purezza: 98 atom % D

Colore e forma: White Solid

Peso molecolare: 495.99

Ref: 3U-D6053

(+/-)-Doxazosin-d8(piperazine-d8)

CAS: 1126848-44-9, 1219803-95-8

Purezza: 98 atom % D

Colore e forma: White Solid

Peso molecolare: 459.53

Ref: 3U-D6015

Doxazosin-d8 Hydrochloride

Prodotto controllato

CAS: 1219803-95-8

Applications Labelled Doxazosin (D537500). Doxazosin is a selective α1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.
References Elliott, H.L., et al.: Brit. J. Clin. Pharmacol., 13, 699 (1982), de Leeuw, P.W., et al.: Eur. J. Clin. Pharmacol., 23, 397 (1982),

Formula: C₂₃D₈H₁₇N₅O₅·ClH

Colore e forma: White

Peso molecolare: 495.99

Ref: TR-D537502

Doxazosin-d8 hydrochloride

CAS: 1219803-95-8

Doxazosin-d8 hydrochloride is an analytical reference standard for HPLC and LCMS, and a drug development impurity. It is a metabolite of doxazosin that is used as an impurity in the manufacture of doxazosin. Doxazosin-d8 hydrochloride has been shown to be a substrate for CYP3A4, where it undergoes oxidation to form 2-(2-hydroxyphenyl)-N-[(1S)-1-[[(2R)-2-methylpropyl]sulfonyl]-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-(2,6 dimethylphenyl)acetamide (CYP3A4). This metabolite may contribute to the pharmacological activity of doxazosin.

Formula: C₂₃H₁₈D₈ClN₅O₅

Purezza: Min. 95%

Peso molecolare: 495.99 g/mol

Ref: 3D-UYB80395