CAS 1222-05-5

Galaxolide

Descrizione:

Galaxolide, con il numero CAS 1222-05-5, è un composto di muschio sintetico ampiamente utilizzato nell'industria delle fragranze. È caratterizzato dal suo piacevole odore muschiato, che ricorda quello del muschio naturale. Galaxolide è un liquido incolore o giallo pallido a temperatura ambiente ed è noto per la sua stabilità e bassa volatilità, rendendolo adatto per l'uso in vari prodotti per la cura personale, detergenti e articoli per la casa. Il composto è lipofilo, permettendo una buona miscelazione con oli e grassi, migliorando la sua efficacia come fissativo per fragranze. Galaxolide è generalmente considerato sicuro per l'uso nei cosmetici, sebbene il suo impatto ambientale abbia sollevato preoccupazioni a causa della sua persistenza negli ambienti acquatici. È classificato come muschio policiclico, che si riferisce a un gruppo di muschi sintetici che possono accumularsi nell'ambiente. In generale, il profilo olfattivo desiderabile e la stabilità di Galaxolide contribuiscono alla sua popolarità nelle formulazioni di fragranze, mentre la ricerca continua a valutare i suoi effetti ecologici.

Formula: C₁₈H₂₆O

InChI: InChI=1S/C18H26O/c1-11-9-19-10-13-7-15-16(8-14(11)13)18(5,6)12(2)17(15,3)4/h7-8,11-12H,9-10H2,1-6H3

InChI key: InChIKey=ONKNPOPIGWHAQC-UHFFFAOYSA-N

SMILES: CC1(C)C=2C(=CC3=C(C2)COCC3C)C(C)(C)C1C

Sinonimi:

• 1,3,4,6,7,8-HEXAHYDRO-4,6,6,7,8,8- HEXAMETHYL CYCLOPENTA-γ-2-BENZOPYRAN
• 1,3,4,6,7,8-Hexahidro-4,6,6,7,8,8-Hexametilindeno[5,6-C]Pirano
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-Hexamethylindeno(5,6-C)Pyr
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-Hexamethylindeno[5,6-C]Pyranne
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethyl-cyclopenta-gamma-2-benzopyran
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclo-penta[g]-2-benzo pyrane
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyrane
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylindeno[5,6-c]pyrane
• 1,3,4,6,7,8-Hexahydro-4,6,6,8,8,8-hexamethylcyclopenta-2-benzopyran
• 1-[2-(Dimethylamino)-1-(4-Methoxyphenyl)Ethyl]Cyclohexanol Hydrochloride (1:1)
• 4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-Hexahydrocyclopenta[G]Isochromene
• Abbalide
• Cimalide 50
• Cyclopenta[g]-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-
• Galaxolide
• Galaxolide 50
• Galaxolide 50BB
• Galaxolide 50IPM
• Galaxolide Abbalide
• Galaxolide White
• Hhcb
• Pearlide
• Venlafaxine

1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran (ca. 50% in Diethyl Phthalate)

CAS: 1222-05-5

Formula: C₁₈H₂₆O

Colore e forma: Colorless to Light yellow clear liquid

Peso molecolare: 258.41

Ref: 3B-G0415

Cyclopenta[g]-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-

CAS: 1222-05-5

Formula: C₁₈H₂₆O

Purezza: 70%

Colore e forma: Liquid

Peso molecolare: 258.3984

Ref: IN-DA0016XN

Galaxolide

CAS: 1222-05-5

Ref: 7W-GK3703

4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-Hexahydrocyclopenta[G]Isochromene

CAS: 1222-05-5

4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-Hexahydrocyclopenta[G]Isochromene

Purezza: 70%

Peso molecolare: 258.40g/mol

Ref: 54-OR1011338

Mix 1 of Musk a. Polycy. Musk Comp. 10 µg/mL in Cyclohexane

CAS: 105-95-3, 1222-05-5, 13171-00-1, 15323-35-0, 21145-77-7, 33704-61-9, 68140-48-7, 81-14-1, 81-15-2, 83-66-9

Formula: C₁₄H₂₂O

Colore e forma: Mixture

Peso molecolare: 206.32

Ref: 04-LA19020100CY

HHCB

CAS: 1222-05-5

Formula: C₁₈H₂₆O

Colore e forma: Neat

Peso molecolare: 258.40

Ref: 04-C14213000

HHCB 10 µg/mL in Isooctane

Prodotto controllato

CAS: 1222-05-5

Formula: C₁₈H₂₆O

Colore e forma: Single Solution

Peso molecolare: 258.40

Ref: 04-A14213000IO-10

Galaxolide

CAS: 1222-05-5

Formula: C₁₈H₂₆O

Peso molecolare: 258.41

Ref: 4Z-G-159001

Galaxolide-13C-d2

CAS: 1222-05-5

Formula: CC₁₇H₂₄D₂O

Peso molecolare: 261.41

Ref: 4Z-G-159002

Galaxolide-d6 (Mixture of Diastereomers) (>80%)

Prodotto controllato

CAS: 1222-05-5

Applications Galaxolide-d6 is the isotope labelled analog of Galaxolide (G189000); a polycyclic musk (PCM) used as a fragrance ingredient in perfumes, soaps, cosmetics and detergents.
References Mori, T. et al.: J. Health Sci., 52, 276 (2006); Chen Y. et al.: Flav. Frag. J., 21, 822 (2006)

Formula: C₁₈H₂₀D₆O

Purezza: >80%

Colore e forma: Neat

Peso molecolare: 264.43541

Ref: TR-G189002

Galaxolide (Mixture of Diastereomers)

Prodotto controllato

CAS: 1222-05-5

Stability Moisture sensitive
Applications Galaxolide is a polycyclic musk (PCM) used as a fragrance ingredient in perfumes, soaps, cosmetics and detergents. It is increasingly found in the Great Lakes. An assessment by Green-Screen for Safer Chemicals indicates that it is toxic to aquatic life.This compound is a contaminant of emerging concern (CECs).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mori, T. et al.: J. Health Sci., 52, 276 (2006); Chen Y., et al.: Flav. Frag. J., 21, 822 (2006); Chem. and Eng. News, May 2 (2016), page 19

Formula: C₁₈H₂₆O

Purezza: >80%

Colore e forma: Colourless

Peso molecolare: 258.40

Ref: TR-G189000

Galaxolide (solution 50% in diethyl phthalate)

Prodotto controllato

CAS: 1222-05-5

Applications Galaxolide is a polycyclic musk (PCM) used as a fragrance ingredient in perfumes, soaps, cosmetics and detergents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mori, T. et al.: J. Health Sci., 52, 276 (2006); Chen Y. et al.: Flav. Frag. J., 21, 822 (2006);

Formula: C₁₈H₂₆O

Colore e forma: Single Solution

Peso molecolare: 258.40

Ref: TR-G189001

Galaxolide - Mixture of Diastereomers

CAS: 1222-05-5

Galaxolide is a mixture of diastereomers that has been shown to inhibit the growth of bacteria in wastewater treatment systems. It also has high resistance to oxidation and biological attack, which makes it an ideal candidate for use as an antimicrobial agent. Galaxolide exhibits strong inhibitory properties against bacterial membrane potentials and mitochondrial membrane potential, and displays antioxidant activity in vitro. The molecular docking analysis of galaxolide showed that it binds to the active site of triclosan-induced peroxidase. This binding inhibits the enzyme activity of this enzyme, which is responsible for oxidative injury in cells. The chemical structures of galaxolide have been determined using a variety of analytical methods, including dispersive solid-phase extraction with fluorescence detection.

Formula: C₁₈H₂₆O

Purezza: Min. 95%

Colore e forma: Yellow Powder

Peso molecolare: 258.4 g/mol

Ref: 3D-FG23642

Galaxolide-13C3 (Mixture of Diastereomers)

Prodotto controllato

CAS: 1222-05-5

Formula: C₃C₁₅H₂₆O

Colore e forma: Neat

Peso molecolare: 261.38

Ref: TR-G189003

Galaxolide solution, 50% in diethyl phthalate

CAS: 1222-05-5

Galaxolide is a synthetic fragrance ingredient. It is a mixture of two isomers, alpha- and beta-galaxolide. Galaxolide has been shown to have antimicrobial properties and can be used in the treatment of wastewater. The analytical method for galaxolide includes dispersive solid phase extraction with benzalkonium chloride (BAC). The BAC forms an ionic complex with galaxolide that can then be extracted into organic solvent. Galaxolide also has high resistance to microbial degradation and can be used as an antimicrobial agent in cosmetics.

Formula: C₁₈H₂₆O

Purezza: Min. 95%

Colore e forma: Clear Liquid

Peso molecolare: 258.4 g/mol

Ref: 3D-FG45940

Galaxolide

CAS: 1222-05-5

Galaxolide can induce estrogenic activity (Estrogen Receptor/ERR), oxidative stress, and genotoxicity. It also stimulates the enzymatic activities of EROD and GST (Glutathione S-transferase).

Formula: C₁₈H₂₆O

Colore e forma: Solid

Peso molecolare: 258.40

Ref: TM-T201465