CAS 122384-88-7

peptide amide associato al diabete umano

Descrizione:

peptide amide associato al diabete umano, noto anche con il suo numero CAS 122384-88-7, è un peptide che svolge un ruolo nella regolazione del metabolismo del glucosio e nella secrezione di insulina. Questo peptide è derivato dalla molecola di proinsulina ed è associato ai processi fisiologici legati al diabete. La sua struttura consiste tipicamente in una sequenza di amminoacidi che contribuiscono alla sua attività biologica, influenzando vari percorsi metabolici. Il peptide è spesso studiato per le sue potenziali implicazioni nella ricerca sul diabete, in particolare per comprendere i meccanismi di resistenza all'insulina e secrezione. In termini di solubilità, è generalmente solubile in soluzioni acquose, il che è tipico per i peptidi. La stabilità di questo peptide può essere influenzata da fattori come pH e temperatura, che sono cruciali per la sua conservazione e gestione in ambienti di laboratorio. In generale, peptide amide associato al diabete umano è significativo nel contesto dei disturbi metabolici e la ricerca in corso continua a esplorare il suo potenziale terapeutico e i meccanismi d'azione nella gestione del diabete.

Formula: C₁₆₅H₂₆₁N₅₁O₅₅S₂

InChI: InChI=1/C165H261N51O55S2/c1-22-75(12)124(159(266)200-95(47-71(4)5)140(247)203-108(64-219)153(260)206-110(66-221)154(261)216-129(84(21)226)163(270)202-105(58-119(174)234)147(254)209-122(73(8)9)157(264)181-61-121(236)187-106(62-217)150(257)198-103(56-117(172)232)148(255)215-128(83(20)225)162(269)190-93(130(175)237)49-87-38-40-89(227)41-39-87)211-132(239)76(13)183-120(235)60-180-136(243)97(50-85-32-25-23-26-33-85)194-144(251)101(54-115(170)230)196-145(252)102(55-116(171)231)197-151(258)107(63-218)205-152(259)109(65-220)204-142(249)99(52-88-59-178-69-182-88)201-158(265)123(74(10)11)210-146(253)96(48-72(6)7)193-141(248)98(51-86-34-27-24-28-35-86)195-143(250)100(53-114(169)229)191-131(238)77(14)184-139(246)94(46-70(2)3)192-137(244)91(37-31-45-179-165(176)177)188-138(245)92(42-43-113(168)228)189-161(268)126(81(18)223)212-133(240)78(15)185-155(262)111-67-272-273-68-112(207-135(242)90(167)36-29-30-44-166)156(263)199-104(57-118(173)233)149(256)214-125(80(17)222)160(267)186-79(16)134(241)213-127(82(19)224)164(271)208-111/h23-28,32-35,38-41,59,69-84,90-112,122-129,217-227H,22,29-31,36-37,42-58,60-68,166-167H2,1-21H3,(H2,168,228)(H2,169,229)(H2,170,230)(H2,171,231)(H2,172,232)(H2,173,233)(H2,174,234)(H2,175,237)(H,178,182)(H,180,243)(H,181,264)(H,183,235)(H,184,246)(H,185,262)(H,186,267)(H,187,236)(H,188,245)(H,189,268)(H,190,269)(H,191,238)(H,192,244)(H,193,248)(H,194,251)(H,195,250)(H,196,252)(H,197,258)(H,198,257)(H,199,263)(H,200,266)(H,201,265)(H,202,270)(H,203,247)(H,204,249)(H,205,259)(H,206,260)(H,207,242)(H,208,271)(H,209,254)(H,210,253)(H,211,239)(H,212,240)(H,213,241)(H,214,256)(H,215,255)(H,216,261)(H4,176,177,179)/t75-,76-,77-,78-,79-,80+,81+,82+,83+,84+,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,122-,123-,124-,125-,126-,127-,128-,129-/m0/s1

Sinonimi:

• Amylin (human)
• H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (Disulfide bond)

Amylin (human)

CAS: 122384-88-7

The amyloidogenic peptide hormone amylin 1-37 (or Islet Amyloid Polypeptide, IAPP), KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY amide, has been isolated from the amyloid-rich pancreases of diabetic patients. hIAPP forms fibrillar peptide deposits in the pancreatic islets of Langerhans, which may be related to death of the insulin-producing islet β-cells in type 2 diabetes mellitus.

Formula: C₁₆₅H₂₆₁N₅₁O₅₅S₂

Purezza: 95.1%

Colore e forma: White

Peso molecolare: 3903.33

Ref: 01-4030200

Amylin, amide, human

CAS: 122384-88-7

Amylin, amide, human(DAP Amide) is a 37-amino acid peptide hormone co-secreted with insulin to regulate postprandial glucose levels.

Formula: C₁₆₅H₂₆₁N₅₁O₅₅S₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 3903.28

Ref: TM-TP1183

Amylin, human amidated

CAS: 122384-88-7

Formula: C₆₇H₉₆N₁₉O₁₉

Purezza: 97%

Peso molecolare: 1471.5950

Ref: IN-DA00176K

Amylin (human)

CAS: 122384-88-7

Amylin (human)

Ref: 54-BIBA1029

Amylin (Human)

CAS: 122384-88-7

Amylin is a peptide hormone that is found in the pancreas. It regulates blood glucose levels and plays an important role in diabetes. Amylin is also used as a research tool for studying the function of ion channels, cell biology, protein interactions, and pharmacology.

Formula: C₁₆₅H₂₆₁N₅₁O₅₅S₂

Purezza: Min. 95%

Peso molecolare: 3,903.3 g/mol

Ref: 3D-PAM-4219-V

Amylin (human) trifluoroacetate salt

CAS: 122384-88-7

Amylin is a hormone that regulates the release of insulin from the pancreas. Amylin is a protein that consists of 39 amino acids, and in its natural form it is not soluble in water. The amyloid fibrils are insoluble aggregates of proteins that can be found in the brain tissue of patients with Alzheimer's disease. Amylin has been shown to have an entrapment efficiency greater than 96% by using polymeric particles with a diameter less than 50 microns. These particles are able to increase water solubility and nutrient metabolism, as well as improve evaporation rates. They also provide an increased surface area for absorption and pharmacological properties. Amylin has been shown to lower postprandial glycemia when used with insulin in type II diabetes mellitus patients, and may also be an anorectic agent.

Formula: C₁₆₅H₂₆₁N₅₁O₅₅S₂

Purezza: Min. 95%

Peso molecolare: 3,903.28 g/mol

Ref: 3D-FA110263