CAS 1228280-29-2

KY 05009

CAS: 1228280-29-2

Formula: C₁₈H₁₆N₄O₂S

Purezza: %

Colore e forma: Solid

Peso molecolare: 352.4102

Ref: IN-DA00A1FY

Ky 05009

CAS: 1228280-29-2

Ky 05009

Purezza: 98%

Peso molecolare: 352.41g/mol

Ref: 54-OR1013615

KY-05009

CAS: 1228280-29-2

KY-05009

Purezza: ≥98%

Peso molecolare: 352.41g/mol

Ref: 54-BUP15621

KY-05009

CAS: 1228280-29-2

KY-05009 blocks TGF-β1 EMT in lung cancer cells, inhibits TNIK, Wnt genes, induces apoptosis, and is an ATP-competitive TNIK inhibitor (Ki = 100 nM).

Formula: C₁₈H₁₆N₄O₂S

Purezza: 99.89%

Colore e forma: Solid

Peso molecolare: 352.41

Ref: TM-T11793

5-(4-METHYLBENZAMIDO)-2-(PHENYLAMINO)THIAZOLE-4-CARBOXAMIDE

CAS: 1228280-29-2

Purezza: 95.0%

Peso molecolare: 352.4100036621094

Ref: 10-F538209

KY-05009

CAS: 1228280-29-2

KY-05009 is a small molecule that inhibits the DNA methyltransferase enzyme. It has been shown to inhibit the transcriptional regulation of epithelial mesenchymal transition (EMT) and signal pathways, such as the Wnt/β-catenin, TGF-β, and PI3K/AKT pathways. KY-05009 has also been found to be cytotoxic to cancer cells in vitro and in vivo. In addition, it has shown significant cytotoxicity in solid tumours in mice. The mechanism of action of this drug is not yet known, but it may be due to its ability to induce apoptosis by inhibiting histone deacetylases or polymerase chain reaction (PCR).

Formula: C₁₈H₁₆N₄O₂S

Purezza: Min. 95%

Peso molecolare: 352.41 g/mol

Ref: 3D-DZB28029