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CAS 123155-04-4

:

2,3-Di-O-metil-6-O-terz-butil-dimetilsilil β-ciclodestrina

Descrizione:
2,3-Di-O-metil-6-O-terz-butil-dimetilsilil β-ciclodestrina è un derivato modificato della β-ciclodextrina, un oligosaccaride ciclico composto da sette unità di glucosio. Questo composto presenta gruppi funzionali specifici che migliorano la sua solubilità e stabilità, rendendolo utile in varie applicazioni, in particolare nella somministrazione e formulazione di farmaci. La presenza di due gruppi metossilici nelle posizioni 2 e 3 e di un gruppo tert-butil-dimetilsililico nella posizione 6 altera significativamente le sue proprietà chimiche, consentendo un miglior interazione con molecole idrofobiche. Questa modifica aumenta la lipofilia della ciclodextrina, facilitando l'incapsulamento di farmaci scarsamente solubili. Inoltre, il voluminoso gruppo sililico fornisce protezione sterica, il che può migliorare la stabilità del composto in varie condizioni. La struttura unica di questo composto consente di formare complessi di inclusione, rendendolo prezioso in applicazioni farmaceutiche, come il miglioramento della biodisponibilità degli ingredienti farmaceutici attivi. In generale, 2,3-Di-O-metil-6-O-terz-butil-dimetilsilil β-ciclodestrina è caratterizzato dalla sua solubilità modificata, stabilità e capacità di formare complessi con varie molecole ospiti.
Formula:C98H196O35Si7
InChI:InChI=1S/C98H196O35Si7/c1-92(2,3)134(36,37)113-50-57-64-71(99-22)78(106-29)85(120-57)128-65-58(51-114-135(38,39)93(4,5)6)122-87(80(108-31)72(65)100-23)130-67-60(53-116-137(42,43)95(10,11)12)124-89(82(110-33)74(67)102-25)132-69-62(55-118-139(46,47)97(16,17)18)126-91(84(112-35)76(69)104-27)133-70-63(56-119-140(48,49)98(19,20)21)125-90(83(111-34)77(70)105-28)131-68-61(54-117-138(44,45)96(13,14)15)123-88(81(109-32)75(68)103-26)129-66-59(52-115-136(40,41)94(7,8)9)121-86(127-64)79(107-30)73(66)101-24/h57-91H,50-56H2,1-49H3/t57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71+,72+,73+,74+,75+,76+,77+,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-/m1/s1
InChI key:InChIKey=YJLSGORJJHKFEN-CUVGCOKVSA-N
SMILES:C(O[Si](C(C)(C)C)(C)C)[C@@H]1[C@@]2([C@H](OC)[C@@H](OC)[C@](O1)(O[C@@]3([C@@H](CO[Si](C(C)(C)C)(C)C)O[C@@]([C@H](OC)[C@H]3OC)(O[C@@]4([C@@H](CO[Si](C(C)(C)C)(C)C)O[C@@]([C@H](OC)[C@H]4OC)(O[C@@]5([C@@H](CO[Si](C(C)(C)C)(C)C)O[C@](O[C@]6([C@H](OC)[C@@H](OC)[C@@](O[C@]7([C@H](OC)[C@@H](OC)[C@@](O[C@]8([C@H](OC)[C@@H](OC)[C@@](O2)(O[C@@H]8CO[Si](C(C)(C)C)(C)C)[H])[H])(O[C@@H]7CO[Si](C(C)(C)C)(C)C)[H])[H])(O[C@@H]6CO[Si](C(C)(C)C)(C)C)[H])[H])([C@H](OC)[C@H]5OC)[H])[H])[H])[H])[H])[H])[H])[H]
Sinonimi:
  • β-Cyclodextrin, 6A,6B,6C,6D,6E,6F,6G-heptakis-O-[(1,1-dimethylethyl)dimethylsilyl]-2A,2B,2C,2D,2E,2F,2G,3A,3B,3C,3D,3E,3F,3G-tetradeca-O-methyl-
  • 6A,6B,6C,6D,6E,6F,6G-Heptakis-O-[(1,1-dimethylethyl)dimethylsilyl]-2A,2B,2C,2D,2E,2F,2G,3A,3B,3C,3D,3E,3F,3G-tetradeca-O-methyl-β-cyclodextrin
  • Heptakis(6-O-tert-butyldimethylsilyl-2,3-di-O-methyl)-β-cyclodextrin
  • 2,4,7,9,12,14,17,19,22,24,27,29,32,34-Tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontane, β-cyclodextrin deriv.
  • 2,3-Di-O-methyl-6-O-tert-butyldimethylsilyl β-cyclodextrin
  • Heptakis(2,3-di-O-Methyl-6-O-tert-butyldiMethylsilyl)cycloMaltoheptaose.
  • Heptakis(2,3-di-O-Methyl-6-O-tert-butyldiMethylsilyl)-β-cyclodextrin
  • 2,3-Dimethyl-6-tert-butyldimethylsilyl-b-cyclodextrin
Ordinare per
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3 prodotti.
  • Heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-b-cyclodextrin
    Glentham
    + Info

    Heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-b-cyclodextrin

    CAS:

    Ref: 7W-GC4427

    ne
    Prezzo su richiesta
  • Heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-β-cyclodextrin
    TRC
    + Info

    Heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-β-cyclodextrin

    Prodotto controllato
    CAS:
    <p>Applications A β-Cyclodextrin derivative.<br>References Yan, D., et al.: Science, 303, 65 (2004), Gou, P.-F., et al.: Biomacromolecules, 11, 934 (2010),<br></p>
    Formula:C98H196O35Si7
    Colore e forma:White
    Peso molecolare:2131.18

    Ref: TR-H281105

    50mg
    170,00€
    100mg
    273,00€
    250mg
    620,00€
  • 2,3-Dimethyl-6-tert-butyldimethylsilyl-b-cyclodextrin
    Biosynth
    + Info

    2,3-Dimethyl-6-tert-butyldimethylsilyl-b-cyclodextrin

    CAS:
    <p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>
    Formula:C98H196O35Si7
    Purezza:Min. 95 Area-%
    Colore e forma:White Off-White Powder
    Peso molecolare:2,131.18 g/mol

    Ref: 3D-OH16463

    1g
    1.995,00€
    50mg
    253,00€
    100mg
    430,00€
    250mg
    699,00€
    500mg
    1.131,00€