CAS 1234423-95-0

17-[[[3-[(4S)-6,8-dicloro-1,2,3,4-tetraidro-2-metil-4-isochinolinil]fenil]solfonil]ammino]-N-[2-[2-[2-[[[3-[(4S)-6,8-dicloro-1,2,3,4-tetraidro-2-metil-4-isochinolinil]fenil]solfonil]ammino]etossi]etossi]etil]-8-osso-12,15-diossa-2,7,9-triazaeptadecanamide

Descrizione:

La sostanza chimica con il nome "17-[[[3-[(4S)-6,8-dicloro-1,2,3,4-tetraidro-2-metil-4-isochinolinil]fenil]solfonil]ammino]-N-[2-[2-[2-[[[3-[(4S)-6,8-dicloro-1,2,3,4-tetraidro-2-metil-4-isochinolinil]fenil]solfonil]ammino]etossi]etossi]etil]-8-osso-12,15-diossa-2,7,9-triazaeptadecanamide" e numero CAS "1234423-95-0" è un composto organico complesso caratterizzato dalla sua intricatissima struttura molecolare, che include più gruppi funzionali come sulfonammidi, amidi e gruppi oxo. La presenza di moieties diclorati e tetraidrossiquinolina suggerisce una potenziale attività biologica, possibilmente come agente farmaceutico. La sua lunga catena di carbonio e i molteplici legami eterei indicano un certo grado di idrofobicità, il che può influenzare la sua solubilità e biodisponibilità. La complessità strutturale del composto può anche suggerire interazioni specifiche con bersagli biologici, rendendolo di interesse nella chimica medicinale. Tuttavia, sarebbero necessari studi dettagliati per chiarire le sue proprietà, inclusa stabilità, reattività e potenziali applicazioni terapeutiche.

Formula: C₅₀H₆₆Cl₄N₈O₁₀S₂

InChI: InChI=1S/C50H66Cl4N8O10S2/c1-61-31-43(41-27-37(51)29-47(53)45(41)33-61)35-7-5-9-39(25-35)73(65,66)59-15-19-71-23-21-69-17-13-57-49(63)55-11-3-4-12-56-50(64)58-14-18-70-22-24-72-20-16-60-74(67,68)40-10-6-8-36(26-40)44-32-62(2)34-46-42(44)28-38(52)30-48(46)54/h5-10,25-30,43-44,59-60H,3-4,11-24,31-34H2,1-2H3,(H2,55,57,63)(H2,56,58,64)/t43-,44-/m0/s1

InChI key: InChIKey=DNHPDWGIXIMXSA-CXNSMIOJSA-N

SMILES: ClC1=C2C([C@@H](CN(C)C2)C3=CC(S(NCCOCCOCCNC(NCCCCNC(NCCOCCOCCNS(=O)(=O)C4=CC(=CC=C4)[C@H]5C=6C(=C(Cl)C=C(Cl)C6)CN(C)C5)=O)=O)(=O)=O)=CC=C3)=CC(Cl)=C1

Sinonimi:

• 17-[[[3-[(4S)-6,8-Dichloro-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl]phenyl]sulfonyl]amino]-N-[2-[2-[2-[[[3-[(4S)-6,8-dichloro-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl]phenyl]sulfonyl]amino]ethoxy]ethoxy]ethyl]-8-oxo-12,15-dioxa-2,7,9-triazaheptadecanamide
• Ibsrela
• AZD 1722
• Tenapanor
• 12,15-Dioxa-2,7,9-triazaheptadecanamide, 17-[[[3-[(4S)-6,8-dichloro-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl]phenyl]sulfonyl]amino]-N-[2-[2-[2-[[[3-[(4S)-6,8-dichloro-1,2,3,4-tetrahydro-2-methyl-4-isoquinolinyl]phenyl]sulfonyl]amino]ethoxy]ethoxy]ethyl]-8-oxo-

Tenapanor

CAS: 1234423-95-0

Tenapanor

Purezza: ≥98%

Peso molecolare: 1145.05g/mol

Ref: 54-BUP07081

Tenapanor

CAS: 1234423-95-0

Tenapanor (RDX 5791), an NHE3 inhibitor, regulates sodium in the gut and kidney with a strong preclinical safety record and minimal side effects.

Formula: C₅₀H₆₆Cl₄N₈O₁₀S₂

Purezza: 99.49% - 99.85%

Colore e forma: Solid

Peso molecolare: 1145.05

Ref: TM-T7587

Tenapanor

CAS: 1234423-95-0

Tenapanor is a novel antidiabetic drug that has been shown to be effective in the treatment of type 2 diabetes. Tenapanor (INN) reduces blood glucose levels by stimulating insulin release from pancreatic beta-cells and increasing insulin sensitivity in peripheral tissues. Tenapanor binds to the ATP-binding site of the phosphoinositide 3-kinase-related protein kinase 1 (PI3K1) enzyme, which is involved in glucose metabolism. It also inhibits phosphodiesterase 4D (PDE4D), an enzyme that degrades cyclic adenosine monophosphate (cAMP). This dual mechanism of action leads to increased insulin secretion and increased insulin sensitivity, which results in improved glycemic control.
Tenapanor has also been shown to improve long-term efficacy and reduce hypoglycemia when used as a pharmacological treatment for type 2 diabetes. The agent binds to ATP-binding sites on PI3K1, which prevents its

Formula: C₅₀H₆₆Cl₄N₈O₁₀S₂

Purezza: Min. 95%

Peso molecolare: 1,145.04 g/mol

Ref: 3D-BT178667

Tenapanor (Butylene-D8)

Prodotto controllato

CAS: 1234423-95-0

Formula: C₅₀D₈H₅₈Cl₄N₈O₁₀S₂

Colore e forma: Neat

Peso molecolare: 1153.098

Ref: TR-D436897

Tenapanor

Prodotto controllato

CAS: 1234423-95-0

Formula: C₅₀H₆₆Cl₄N₈O₁₀S₂

Colore e forma: Neat

Peso molecolare: 1145.049

Ref: TR-T123440