CAS 1235-82-1

Cloridrato di biperidene

Descrizione:

Cloridrato di biperidene è un farmaco anticolinergico sintetico utilizzato principalmente nel trattamento del morbo di Parkinson e dei sintomi extrapiramidali indotti da farmaci. Funziona bloccando i recettori dell'acetilcolina, aiutando così a ripristinare l'equilibrio tra dopamina e acetilcolina nel sistema nervoso centrale. Questo composto appare come una polvere cristallina bianca o bianco sporco ed è solubile in acqua, rendendolo adatto per somministrazione orale e parenterale. La sua struttura chimica include un anello di piperidina, che è caratteristico di molti agenti anticolinergici. Cloridrato di biperidene viene tipicamente somministrato sotto forma di compresse o come soluzione iniettabile, e i suoi effetti farmacologici possono includere riduzione della rigidità muscolare e tremori. Gli effetti collaterali comuni possono includere secchezza delle fauci, visione offuscata, stitichezza e ritenzione urinaria, che sono tipici dei farmaci anticolinergici. A causa del suo meccanismo d'azione, è importante monitorare i pazienti per potenziali effetti cognitivi, specialmente nella popolazione anziana. In generale, Cloridrato di biperidene gioca un ruolo significativo nella gestione dei sintomi associati ai disturbi del movimento.

Formula: C₂₁H₂₉NO·ClH

InChI: InChI=1S/C21H29NO.ClH/c23-21(19-7-3-1-4-8-19,11-14-22-12-5-2-6-13-22)20-16-17-9-10-18(20)15-17;/h1,3-4,7-10,17-18,20,23H,2,5-6,11-16H2;1H

InChI key: InChIKey=RDNLAULGBSQZMP-UHFFFAOYSA-N

SMILES: C(CCN1CCCCC1)(O)(C2C3CC(C2)C=C3)C4=CC=CC=C4.Cl

Sinonimi:

• 1-(Bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride
• 1-(Bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride (1:1)
• 1-Bicyclo[2.2.1]Hept-5-En-2-Yl-1-Phenyl-3-Piperidin-1-Ylpropan-1-Ol Hydrochloride
• 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-ylpropan-1-olhydrochlorid
• 1-Bicycloheptenyl-1-phenyl-3-piperidinopropanol Hydrochloride
• 1-Piperidinepropanol, .alpha.-bicyclo[2.2.1]hept-5-en-2-yl-.alpha.-phenyl-, hydrochloride
• 1-Piperidinepropanol, alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-, hydrochloride (1:1)
• 1-Piperidinepropanol, α-5-norbornen-2-yl-α-phenyl-, hydrochloride
• 1-Piperidinepropanol, α-bicyclo[2.2.1]hept-5-en-2-yl-α-phenyl-, hydrochloride
• 1-Piperidinepropanol, α-bicyclo[2.2.1]hept-5-en-2-yl-α-phenyl-, hydrochloride (1:1)
• 1235-82-1
• 214-976-2
• Akineton hydrochloride
• Akinophyl
• Biperidene hydrochloride
• NSC 170950
• NSC 84989
• Tasmolin

Biperiden.HCl, 1mg/ml in Methanol (as free base)

CAS: 1235-82-1

Colore e forma: Single Solution

Ref: LP-BIP-1918-HC-1LM

BIPERIDEN HYDROCHLORIDE CRS

CAS: 1235-82-1

BIPERIDEN HYDROCHLORIDE CRS

Formula: C₂₁H₃₀ClNO

Colore e forma: Powder

Peso molecolare: 347.922

Ref: 41-B1120000

BIPERIDEN HYDROCHLORIDE RS

CAS: 1235-82-1

BIPERIDEN HYDROCHLORIDE RS

Formula: C₂₁H₃₀ClNO

Colore e forma: Powder

Peso molecolare: 347.922

Ref: 41-ICRS46476

Biperiden (hydrochloride)

CAS: 1235-82-1

Formula: C₂₁H₃₀ClNO

Purezza: 98%

Peso molecolare: 347.9220

Ref: IN-DA000KOS

Biperiden HCl (Mixture of Diastereomers)

CAS: 1235-82-1

Formula: C₂₁H₂₉NO·HCl

Peso molecolare: 311.47 36.46

Ref: 4Z-B-111018

1-(Bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride

CAS: 1235-82-1

1-(Bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride

Purezza: 98%

Peso molecolare: 347.93g/mol

Ref: 54-OR1073974

Biperiden hydrochloride

CAS: 1235-82-1

Formula: C₂₁H₃₀ClNO

Peso molecolare: 347.92

Ref: 7W-GP6565

Biperiden Hydrochloride

CAS: 1235-82-1

Biperiden HCl is an anti-Parkinson's drug, blocks M1 receptors, manages all Parkinson's types, and is FDA-approved. Non-toxic at 0.11 mg/kg to rats' cognition.

Formula: C₂₁H₃₀ClNO

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 347.92

Ref: TM-T14614

Biperiden Hydrochloride

CAS: 1235-82-1

Formula: C₂₁H₂₉NO·ClH

Colore e forma: Neat

Peso molecolare: 347.92

Ref: 86-MM0288.00

Biperiden.HCl

CAS: 1235-82-1

Colore e forma: Neat

Ref: LP-BIP-1918-HC-10

Biperiden Hydrochloride

CAS: 1235-82-1

Colore e forma: Neat

Ref: 61-FOR0288.00

Biperiden hydrochloride

CAS: 1235-82-1

Colore e forma: Neat

Ref: 04-CA10628100

Biperiden HCl - Bio-X ™

Prodotto controllato

CAS: 1235-82-1

Biperiden is a muscarinic antagonist drug that is used in the treatment of Parkinson's disease and other conditions. Biperiden binds to the dopamine D2 receptor, which inhibits the release of dopamine from presynaptic neurons. It also possesses nicotinolytic activity.

Formula: C₂₁H₂₉NO·HCl

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 347.92 g/mol

Ref: 3D-FB64957

Biperiden hydrochloride

Prodotto controllato

CAS: 1235-82-1

Biperiden hydrochloride is an anticholinergic medication, which is a synthetic derivative. It exerts its effects primarily through the central nervous system by blocking acetylcholine receptors. This blockade reduces the activity of acetylcholine, a neurotransmitter, which plays a role in muscle contractions and various neural functions. By antagonizing the muscarinic receptors, Biperiden hydrochloride helps in modulating the balance between neurotransmitters in the brain.

Formula: C₂₁H₂₉NO•HCl

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 347.92 g/mol

Ref: 3D-BB183958

Biperiden hydrochloride

Prodotto controllato

CAS: 1235-82-1

Biperiden hydrochloride is a potent, centrally acting anticholinergic agent that has been used to treat Parkinson's disease and other extrapyramidal disorders. Biperiden hydrochloride works by blocking the transmission of nerve impulses in the brain by inhibiting acetylcholine at the synapse. It also inhibits dopamine release and blocks postsynaptic dopamine receptors. Biperiden hydrochloride is used in vitro to study the effects of drugs on human serum and urine samples, as well as for diagnostic purposes in vivo. In vitro assays are also conducted to study the effect of drugs on locomotor activity and symptoms in animals. Biperiden hydrochloride can be combined with mianserin hydrochloride or fluorescein angiography to study the function of dopaminergic systems in vivo.

Formula: C₂₁H₃₀ClNO

Purezza: Min. 94 Area-%

Peso molecolare: 347.93 g/mol

Ref: 3D-J-004957

Biperiden Hydrochloride-d5 (Mixture of Diastereomers)

Prodotto controllato

CAS: 1235-82-1

Applications Biperiden Hydrochloride-d5 is the isotope labelled analog of Biperiden Hydrochloride (B397825); an antiparkinsonian and non-selective muscarinic receptor antagonist. Biperiden is used for the adjunctive treatment of all forms of Parkinson′s Disease (postencephalitic, idiopathic, and arteriosclerotic) and is also commonly used to improve parkinsonian signs and symptoms related to antipsychotic drug therapy.
References Patela, Y., et al.: Talanta, 47, 625 (1998); Bebawy, L., et al: J. Pharm. Biomed. Anal., 20, 663 (1999); Dinc, E., et al.: J. Pharm. Biomed. Anal., 28, 591 (2002)

Formula: C₂₁D₅H₂₄NO·HCl

Colore e forma: Off-White

Peso molecolare: 352.953

Ref: TR-B397827