CAS 1256584-81-2
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Ref: 4Z-A-239041
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta8-(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)-9-ethyl-6,11-dihydro-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
CAS:Prodotto controllato<p>Applications 8-(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)-9-ethyl-6,11-dihydro-6,6-dimethyl-11-oxo-5H-benzo[b]carbazole-3-carbonitrile is an intermediate used in the synthesis of Alectinib M4 metabolite (A521150), which is the major active metabolite of Alectinib. Alectinib is an anaplastic lymphoma kinase (ALK) inhibitor and is used to treat non-small-cell lung cancer by blocking the activity of anaplastic lymphoma kinase (ALK).<br>References Heinig, K., et al.: Bioanalysis, 8, 1465-79 (2016); Morcos, P.N., et al.: Xenobiotica, 47, 217-29 (2017);<br></p>Formula:C28H29N3O3Colore e forma:NeatPeso molecolare:455.548
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