CAS 125700-67-6

O-(Benzotriazol-1-il)-N,N,N′,N′-tetrametiluronio tetrafluoroborato

Descrizione:

O-(Benzotriazol-1-il)-N,N,N′,N′-tetrametiluronio tetrafluoroborato, con numero CAS 125700-67-6, è un composto chimico comunemente usato come reagente di accoppiamento nella sintesi di peptidi e in altre reazioni organiche. Presenta un gruppo benzotriazolo, che ne migliora la reattività e la stabilità, rendendolo efficace nel facilitare la formazione di legami ammidici. La presenza del gruppo tetrametiluronio contribuisce alla sua capacità di attivare gli acidi carbossilici, promuovendo la loro conversione in specie più reattive. Questo composto è tipicamente un solido bianco a bianco sporco ed è solubile in solventi organici polari. Il suo controione tetrafluoroborato fornisce ulteriori caratteristiche di stabilità e solubilità. Come per molti reagenti di accoppiamento, è importante maneggiare questa sostanza con cura, poiché può comportare rischi per la salute se inalata o ingerita. Devono essere seguiti protocolli di sicurezza di laboratorio adeguati quando si lavora con questo composto, incluso l'uso di dispositivi di protezione individuale e metodi appropriati di smaltimento dei rifiuti.

Formula: C₁₁H₁₆N₅O·BF₄

InChI: InChI=1S/C11H16N5O.BF4/c1-13(2)11(14(3)4)15-9-7-5-6-8-10(9)16(17)12-15;2-1(3,4)5/h5-8H,1-4H3;/q+1;-1

InChI key: InChIKey=ZXZJCMUCQIOBGO-UHFFFAOYSA-N

SMILES: C(N(C)C)(N(C)C)=[N+]1C=2C(N(=O)=N1)=CC=CC2.[B+3]([F-])([F-])([F-])[F-]

Sinonimi:

• (Benzotriazol-1-yloxy-dimethylamino-methylene)dimethylammonium tetrafluoroborate
• 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, tetrafluoroborate(1-)
• 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, tetrafluoroborate(1-) (1:1)
• 2-(1H-Benzotriazol-1-YL)-1,1,3,3-tetramethyluronium Tetrafluoroborate
• 2-(1H-Benzotriazol-1-yl)-N,N,N′,N′-tetramethylammonium tetrafluoroborate
• Benzotriazol-1-yl-tetramethyluroniumtetrafluoroborate
• Knorr Reagent
• N,N,N',N'-tetramethyl-O-(Benzotriazol-1-YL)uronium Tetrafluoroborate
• N-[(1H-benzotriazol-1-yloxy)(dimethylamino)methylidene]-N-methylmethanaminium Tetrafluoroborate
• O-(1H-Benzotriazol-1-YL)-1,1,3,3-tetramethyl-uronium Tetrafluoroborate
• O-(1H-Benzotriazol-1-YL)-N,N,N',N'-tetramethyluronium Tetrafluoroborate
• O-(1H-Benzotriazole-1-YL) N,N,N',N'-tetramethyl uronium Tetrafluoroborate
• O-(Benzotriazol-1-yl)-N,N,N',N'-tetra methyluronium Tetrafluoroborate
• O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate
• O-(Benzotriazol-l-yl)-N,N,N,N,-tetramethyluronium Tetrafluoroborate
• O-Benzotriazol-1-yl-tetramethyluronium tetrafluoroborate
• O-Benzotriazolyl tetramethylisouronium tetrafluoroborate

TBTU [Coupling Reagent for Peptide]

CAS: 125700-67-6

Formula: C₁₁H₁₆BF₄N₅O

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 321.09

Ref: 3B-B1658

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate, 99%

CAS: 125700-67-6

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate is used as used for solid-phase peptide synthesis. It is also used to study ten different phosphonium and uronium salt-based coupling reagents, which are used to synthesize four peptides. This Thermo Scientific Chemicals brand p

Formula: C₁₁H₁₆BF₄N₅O

Purezza: 99%

Colore e forma: Crystalline powder or powder, White to cream

Peso molecolare: 321.09

Ref: 02-L13470

TBTU

CAS: 125700-67-6

TBTU is successfully used as coupling reagent in solid phase peptide synthesis. It acts as an excellent activating reagent causing low racemization during condensation of peptide segments. A study of the structure of TBTU in solid state as well as in solution by Abdelmoty et al. showed that the compound is a guanidinium N-oxide and not an uronium salt.

Formula: C₁₁H₁₆BF₄N₅O

Colore e forma: White

Peso molecolare: 321.09

Ref: 01-4013268

1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, tetrafluoroborate(1-) (1:1)

CAS: 125700-67-6

Formula: C₁₁H₁₆BF₄N₅O

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 321.0823

Ref: IN-DA000OI0

O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate

CAS: 125700-67-6

O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate

Formula: C₁₁H₁₆N₅O·BF₄

Purezza: ≥95%

Colore e forma: white crystalline powder

Peso molecolare: 321.08224g/mol

Ref: 54-PC0921

TBTU

CAS: 125700-67-6

Formula: C₁₁H₁₆BF₄N₅O

Purezza: ≥ 99.0%

Colore e forma: White to almost white powder

Peso molecolare: 321.08

Ref: 7W-GE5057

O-(Benzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium tetrafluoroborate

CAS: 125700-67-6

Formula: C₁₁H₁₆BF₄N₅O

Purezza: 98.0%

Colore e forma: Solid

Peso molecolare: 321.09

Ref: 10-F009020

TBTU

CAS: 125700-67-6

TBTU is an aminium coupling reagent used for amide and ester synthesis. TBTU is a stable, efficient and reactive reagent suitable for solution and solid-phase peptide synthesis. With TBTU high yields, racemisation suppression and fast reaction times are achieved. TBTU contains the carbodiimide and benzotriazole moieties, generates HOBt and water-soluble by-products. TBTU can be used in its polymer-bound form as a solid-supported peptide coupling reagent efficient even in presence of water and can be easily separated and regenerated after the reaction. TBTU finds application in the synthesis of biologically active peptides, such as azapeptides.

Formula: C₁₁H₁₆N₅O·BF₄

Purezza: Min. 99 Area-%

Colore e forma: White Off-White Powder

Peso molecolare: 321.08 g/mol

Ref: 3D-FT07096

TBTU Reagent

CAS: 125700-67-6

TBTU Reagent is a combination of two reagents that are used for peptide synthesis and purification. TBTU is an amide coupling reagent that reacts with the carboxyl group of an ester to form a reactive intermediate, which then reacts with the amino group of an amide. This reaction forms an amide bond between the carboxyl group of the ester and the amino group of the amide. TBTU Reagent has been used in vitro assays to measure pharmacological activities such as anti-inflammatory effects and antimicrobial effects. TBTU Reagent has also been used to prepare mouse monoclonal antibodies against toll-like receptor 4 (TLR4).

Formula: C₁₁H₁₆N₅OBF₄

Purezza: Min. 95%

Peso molecolare: 321.08 g/mol

Ref: 3D-KTB-1066-PI

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

CAS: 125700-67-6

Please enquire for more information about O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₁H₁₆BF₄N₅O

Peso molecolare: 321.08 g/mol

Ref: 3D-J-523817

TBTU extrapure, 98%

CAS: 125700-67-6

Formula: C₁₁H₁₆BF₄N₅O

Purezza: min. 98%

Colore e forma: White, Crystalline powder

Peso molecolare: 321.08

Ref: SR-47064

O-(Benzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium Tetrafluoroborate

Prodotto controllato

CAS: 125700-67-6

Applications O-(Benzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium Tetrafluoroborate is used in the synthesis of tetrapeptoid analogues of the antiprotocoal compound Apicidin (A726300). Also used in the synthesis of acid based t-antigen glycodendrimers.
References Murray, P. et al.: Bioorg. Med. Chem. Lett., 11, 773 (2001); Roy, R. et al.: J. Am. Chem. Soc., 123, 1809 (2001);

Formula: C₁₁H₁₆BF₄N₅O

Colore e forma: Neat

Peso molecolare: 321.08

Ref: TR-B206995