CAS 126-07-8

Griseofulvina

Descrizione:

Griseofulvina è un farmaco antifungino utilizzato principalmente per trattare le infezioni da dermatofiti, in particolare quelle che colpiscono la pelle, i capelli e le unghie. È derivato dalla muffa Penicillium griseofulvum e agisce inibendo la mitosi delle cellule fungine, impedendo così la crescita e la riproduzione dei funghi. Griseofulvina è caratterizzato dalla sua struttura cristallina ed è tipicamente somministrato per via orale. È poco solubile in acqua ma più solubile in solventi organici, il che influisce sulla sua assorbimento e biodisponibilità. La sostanza è nota per la sua emivita relativamente lunga, che consente una somministrazione una volta al giorno in molti casi. Gli effetti collaterali comuni possono includere disturbi gastrointestinali, mal di testa e potenziali reazioni allergiche. Griseofulvina è controindicato in alcune popolazioni, come le persone in gravidanza, a causa di potenziali effetti teratogeni. La sua efficacia è spesso valutata attraverso la valutazione clinica e test di laboratorio per confermare la presenza di specie fungine suscettibili. In generale, Griseofulvina rimane un'opzione terapeutica significativa nella gestione di specifiche infezioni fungine.

Formula: C₁₇H₁₇ClO₆

InChI: InChI=1/C17H19ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h7-8,12H,5-6H2,1-4H3/t8-,12?,17+/m1/s1

InChI key: InChIKey=DDUHZTYCFQRHIY-RBHXEPJQSA-N

SMILES: O=C1[C@@]2(OC=3C1=C(OC)C=C(OC)C3Cl)C(OC)=CC(=O)C[C@H]2C

Sinonimi:

• (1′S,6′R)-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione
• (2R,6'S)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
• (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
• (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohexane]-3,4'-dione
• (2S,6'S)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
• 7-Chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione
• 7-Chloro-2',4,6-trimethoxy-6'β-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione
• 7-Chloro-2′,4,6-trimethoxy-6′β-methylspiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione
• 7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
• Amudane
• Curling factor
• Fulcin
• Fulvicin
• Fulvicin Bolus
• Fulvicin P/G
• Fulvicin U/F
• Fulvidex
• Fulvina
• Fulvinil
• Fulvistatin
• Gricin
• Grifulin
• Grifulvin
• Grifulvin V
• Gris-PEG
• Grisactin
• Grisefulin
• Griseofulvin Powder
• Griseofulvina
• Griseofulvine
• Griseovin
• Grisofulvin
• Grisovin
• Grisovin FP
• Grysio
• Idifulvin
• Lamoryl
• Likuden
• Neo-Fulcin
• Polygris
• Poncyl
• Poncyl FP
• Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'S,6'R)-
• Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'S-trans)-
• Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'β-methyl-
• Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione,7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'R-trans)-
• Spiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′-methyl-, (1′S,6′R)-
• Spiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′-methyl-, (1′S-trans)-
• Spiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′β-methyl-
• Spirofulvin
• Sporostatin
• Xuanjing
• (+)-Griseofulvin
• 7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYL-, (1'S-TRANS)-SPIRO(BENZOFURAN-2(3H),1'-(2)CYCLOHEXENE)-3,4'-DIONE
• (2s-trans)-7-chloro-2’,4,6-trimethoxy-6’-methylspiro[benzofuran-2(3h),1’-[2]cy
• (2S)-TRANS-7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYLSPIRO(BENZOFURAN-2[3H],1'-[2]CYCLOHEXENE)-3,4'-DIONE
• Delmofulvina
• (2s-trans)-xy-6’-methyl
• 7-chloro-4,6,2’-trimethoxy-6’-methylgris-2’-en-3,4’-dione
• curlingfactor
• 7-Chloro-2',4,6-trimethoxy-6'beta-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione
• [2S-TRANS]-7-CHLORO-2,4,6-TRIMETHOXY-6'-METHYLSPIRO[BENZOFURAN-2(3H), 1'(2)-CYCLOHEXANE]-3,4'-DIONE
• (+)-griseofulvi
• -6’-beta-methyl-
• 7-Chloro-4,6,2'-trimethoxy-6'-methylgris-2'-en-3,4'-dione
• 2’-en-4’-one)
• clohexene]-3,4’-dione
• 6-dimethoxycoumaran-3-one-2-spiro-1’-(2’-methoxy-6’-methylcyclohex-7-chloro-

(+)-Griseofulvin

CAS: 126-07-8

Formula: C₁₇H₁₇ClO₆

Purezza: >95.0%(HPLC)(qNMR)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 352.77

Ref: 3B-G0384

(+)-Griseofulvin, 97%

CAS: 126-07-8

Griseofulvin is an antifungal drug. It is used both in animal and in humans, to treat ringworm infections of the skin and nails. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy br

Formula: C₁₇H₁₉ClO₆

Purezza: 97%

Colore e forma: White, Powder

Peso molecolare: 354.78

Ref: 02-B23521

Griseofulvin

CAS: 126-07-8

Formula: C₁₇H₁₇ClO₆

Purezza: 99.11%

Colore e forma: Brownish. Powder

Peso molecolare: 353.0

Ref: 8R-CL0363

Griseofulvin

CAS: 126-07-8

Colore e forma: Neat

Ref: 61-FOR0582.00

GRISEOFULVIN RS

CAS: 126-07-8

GRISEOFULVIN RS

Formula: C₁₇H₁₇ClO₆

Peso molecolare: 352.7663

Ref: 41-ICRS0322

Griseofulvin

CAS: 126-07-8

Antibiotics nesoi

Formula: C₁₇H₁₇ClO₆

Colore e forma: White Cream Powder

Peso molecolare: 352.07137

Ref: 45-1299007

Griseofulvin Permeability Diameter

CAS: 126-07-8

Antibiotics nesoi

Formula: C₁₇H₁₇ClO₆

Colore e forma: White Off-White Powder

Peso molecolare: 352.77

Ref: 45-1299200

(2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione

CAS: 126-07-8

Formula: C₁₇H₁₇ClO₆

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 352.7663

Ref: IN-DA0032AV

Griseofulvin

CAS: 126-07-8

Griseofulvin (Fulvicin) is an antifungal agent used in the treatment of TINEA infections.

Formula: C₁₇H₁₇ClO₆

Purezza: 97.06% - 98.12%

Colore e forma: Stout Octahedra Or Rhombs From Benzene

Peso molecolare: 352.77

Ref: TM-T1382

Griseofulvin

CAS: 126-07-8

Griseofulvin

Purezza: ≥95%

Peso molecolare: 352.77g/mol

Ref: 54-BUP18502

Griseofulvin

CAS: 126-07-8

Formula: C₁₇H₁₇ClO₆

Colore e forma: White To Off-White Solid

Peso molecolare: 352.77

Ref: 4Z-G-082

Griseofulvin, EP grade

CAS: 126-07-8

Formula: C₁₇H₁₇ClO₆

Purezza: ≤ 0.75%

Colore e forma: White or pale yellow powder

Peso molecolare: 352.77

Ref: 7W-GA3498

Griseofulvin-13C-d3

CAS: 126-07-8

Formula: C₁₆₁₃CH₁₄D₃ClO₆

Colore e forma: White To Off-White Solid

Peso molecolare: 356.78

Ref: 4Z-G-088

Griseofulvin

CAS: 126-07-8

Formula: C₁₇H₁₇ClO₆

Purezza: 97.0 - 102.0 % (dried basis)

Colore e forma: White or off-white powder

Peso molecolare: 352.77

Ref: 7W-GA6599

(+)-Griseofulvin

CAS: 126-07-8

(+)-Griseofulvin

Purezza: 98%

Peso molecolare: 352.77g/mol

Ref: 54-OR1029322

Griseofulvin

Prodotto controllato

CAS: 126-07-8

Formula: C₁₇H₁₇ClO₆

Colore e forma: Neat

Peso molecolare: 352.77

Ref: 04-C14056500

Griseofulvin

Prodotto controllato

CAS: 126-07-8

Formula: C₁₇H₁₇ClO₆

Colore e forma: Neat

Peso molecolare: 352.77

Ref: 86-MM0582.00

Griseofulvin 100 µg/mL in Acetonitrile

CAS: 126-07-8

Formula: C₁₇H₁₇ClO₆

Colore e forma: Single Solution

Peso molecolare: 352.77

Ref: 04-V14056500AL-100

Griseofulvin

Prodotto controllato

CAS: 126-07-8

Applications It is an antifungal drug. It is used both in animal and in humans, to treat rigworm infections of the skin and nails. It is derived from the mold Penicillium griseofulvum.Environmental contaminants; Food contaminants
References Oxford, et al.: Biochem. J., 33, 240 (1939), Townley, E.R., et al.: Anal. Profiles Drug Subs., 8, 219 (1979),

Formula: C₁₇H₁₇ClO₆

Colore e forma: Off-White

Peso molecolare: 352.77

Ref: TR-G787500

Griseofulvin

CAS: 126-07-8

Anti-fungal; microtubule polymerization inhibitor

Formula: C₁₇H₁₇ClO₆

Purezza: Min. 97 Area-%

Colore e forma: Powder

Peso molecolare: 352.77 g/mol

Ref: 3D-FG23704

Griseofulvin - Bio-X ™

CAS: 126-07-8

Griseofulvin is an antifungal drug used to treat several types of dermatophytosis (ringworm). This includes fungal infections of the nails, scalp and the skin when antifungal creams have not worked. It is suggested that it prevents nuclear acid production and fungal cell mitosis. Additionally, through binding to alpha and beta tubulin, it interferes with the function of the spindle and cytoplasmic microtubules.

Formula: C₁₇H₁₇ClO₆

Purezza: Min. 97 Area-%

Colore e forma: Powder

Peso molecolare: 352.77 g/mol

Ref: 3D-BT164513

(2S,6’R)-7-chloro-2′,4,6-trimethoxy-6′-methyl-3H-spiro[1-benzofuran-2,1′-cyclohexan]-2′-ene-3,4′-dione

CAS: 126-07-8

Formula: C₁₇H₁₇ClO₆

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 352.77

Ref: 10-F354301

Griseofulvin

CAS: 126-07-8

Griseofulvin

Formula: C₁₇H₁₇ClO₆

Purezza: 99.8% / 98.3%

Colore e forma: White

Peso molecolare: 352.07137

Ref: 47-180