CAS 1264-62-6

Eritromicina etilsuccinato

Descrizione:

Eritromicina etilsuccinato è un antibiotico appartenente alla classe dei macrolidi, utilizzato principalmente per trattare varie infezioni batteriche. È un derivato semisintetico dell'eritromicina, che ne migliora la stabilità e la biodisponibilità. Il composto è caratterizzato dalla sua capacità di inibire la sintesi proteica batterica legandosi alla subunità ribosomiale 50S, rendendolo efficace contro una gamma di batteri Gram-positivi e alcuni Gram-negativi. Eritromicina etilsuccinato viene tipicamente somministrato per via orale ed è spesso formulato come un pro-farmaco, che viene convertito in eritromicina nel corpo. È noto per la sua tossicità relativamente bassa e per gli effetti collaterali, sebbene possano verificarsi disturbi gastrointestinali. La sostanza è solubile in solventi organici ma ha una solubilità limitata in acqua, il che influisce sulla sua formulazione e somministrazione. Inoltre, è importante considerare le potenziali interazioni farmacologiche e i modelli di resistenza quando si utilizza questo antibiotico in contesti clinici. In generale, Eritromicina etilsuccinato rimane un'opzione preziosa nel trattamento delle infezioni, in particolare nei pazienti allergici alla penicillina.

Formula: C₄₃H₇₅NO₁₆

InChI: InChI=1S/C43H75NO16/c1-15-29-43(11,52)36(48)24(5)33(47)22(3)20-41(9,51)38(25(6)34(26(7)39(50)57-29)59-32-21-42(10,53-14)37(49)27(8)56-32)60-40-35(28(44(12)13)19-23(4)55-40)58-31(46)18-17-30(45)54-16-2/h22-29,32,34-38,40,48-49,51-52H,15-21H2,1-14H3/t22-,23-,24+,25+,26-,27+,28+,29-,32+,34+,35-,36-,37+,38-,40+,41-,42-,43-/m1/s1

InChI key: InChIKey=NSYZCCDSJNWWJL-YXOIYICCSA-N

SMILES: O(C(CCC(OCC)=O)=O)[C@H]1[C@H](O[C@@H]2[C@@H](C)[C@H](O[C@H]3C[C@](OC)(C)[C@@H](O)[C@H](C)O3)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]2(C)O)O[C@H](C)C[C@@H]1N(C)C

Sinonimi:

• (2R,3S,4R,6S)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl]oxy}-6-methyltetrahydro-2H-pyran-3-yl ethyl butanedioate (non-preferred name)
• (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydropyran-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
• 4-(dimethylamino)-2-({14-ethyl-7,12,13-trihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy]-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl}oxy)-6-methyltetrahydro-2H-pyran-3-yl ethyl butanedioate (non-preferred name)
• 4-Ethoxy-4-Oxo-Butanoate
• Anamycin
• Arpimycin
• Durapaediat
• E-Mycin e
• Eritrocina
• EryPed
• Eryliquid
• Erythro ES
• Erythro-Holz
• Erythrocin ethyl succinate
• Erythromycin Ethly Succinate.
• Erythromycin Ethyl Succinate
• Erythromycin Ethylsuccinate
• Erythromycin, 2′-(ethyl butanedioate)
• Erythromycin, 2′-(ethyl succinate)
• Erythromycin, mono(ethyl succinate) (ester)
• Erythroped
• Esinol
• Evesin
• Monomycin
• Oxacyclotetradecane, erythromycin deriv.
• Paediathrocin
• Pediamycin
• Refkas
• Sigapedil
• Succinic acid, ethyl ester, monoester with erythromycin

Erythromycin ethyl succinate

CAS: 1264-62-6

Erythromycin ethyl succinate

Formula: C₄₃H₇₅NO₁₆

Colore e forma: Off-White

Peso molecolare: 862.0527

Ref: 47-798

ERYTHROMYCIN ETHYLSUCCINATE RS

CAS: 1264-62-6

ERYTHROMYCIN ETHYLSUCCINATE RS

Formula: C₄₃H₇₅NO₁₆

Peso molecolare: 862.0527

Ref: 41-ICRS46470

ERYTHROMYCIN ETHYLSUCCINATE CRS

CAS: 1264-62-6

ERYTHROMYCIN ETHYLSUCCINATE CRS

Formula: C₄₃H₇₅NO₁₆

Peso molecolare: 862.0527

Ref: 41-E1500000

ERYTHROMYCIN ETHYLSUCCINATE FOR IMPURITY P IDENTIFICATION CRS

CAS: 1264-62-6

ERYTHROMYCIN ETHYLSUCCINATE FOR IMPURITY P IDENTIFICATION CRS

Formula: C₄₃H₇₅NO₁₆

Peso molecolare: 862.0527

Ref: 41-Y0001845

Erythromycin Ethylsuccinate

CAS: 1264-62-6

Erythromycin and its derivatives; salts thereof

Formula: C₄₃H₇₅NO₁₆

Colore e forma: White Powder

Peso molecolare: 861.50859

Ref: 45-1245008

(2S,3R,4S,6R)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxo-1-oxacyclotetradecan-6-yl]oxy}-6-methyloxan-3-yl 1-ethyl butanedioate

CAS: 1264-62-6

Formula: C₄₃H₇₅NO₁₆

Colore e forma: Solid

Peso molecolare: 862.0527

Ref: IN-DA000SQT

Erythromycin ethylsuccinate

CAS: 1264-62-6

Erythromycin ethylsuccinate (EES) is a macrolide antibiotic, produced by Streptomyces erythreus.

Formula: C₄₃H₇₅NO₁₆

Purezza: 77% - 98%

Colore e forma: White Or Slightly Yellow Crystalline Powder White To Yellowish Crystalline Solid

Peso molecolare: 862.05

Ref: TM-T0474

Erythromycin ethylsuccinate

CAS: 1264-62-6

Erythromycin ethylsuccinate

Purezza: ≥70%

Peso molecolare: 862.05g/mol

Ref: 54-BUP16717

Erythromycin Ethylsuccinate

CAS: 1264-62-6

Erythromycin Ethylsuccinate

Purezza: ≥765IU/mg

Peso molecolare: 862.05g/mol

Ref: 54-OR1027491

Erythromycin Ethylsuccinate-13C-d3

CAS: 1264-62-6

Formula: C₄₂₁₃CH₇₂D₃NO₁₆

Colore e forma: White To Off-White Solid

Peso molecolare: 866.07

Ref: 4Z-E-2015

Erythromycin Ethylsuccinate

CAS: 1264-62-6

Formula: C₄₃H₇₅NO₁₆

Colore e forma: White To Off-White Solid

Peso molecolare: 862.06

Ref: 4Z-E-2040

Erythromycin-ethyl succinate

Prodotto controllato

CAS: 1264-62-6

Formula: C₄₃H₇₅NO₁₆

Colore e forma: Off-White

Peso molecolare: 862.05

Ref: 04-C13203520

Erythromycin Ethylsuccinate-D5

CAS: 1264-62-6

Formula: C₄₃H₇₀NO₁₆D₅

Peso molecolare: 867.10

Ref: 4Z-E-2014

Erythromycin Ethyl Succinate

CAS: 1264-62-6

Formula: C₄₃H₇₅NO₁₆

Peso molecolare: 862.05

Ref: ST-EA-CP-E18015

Erythromycin Ethyl Succinate

Prodotto controllato

CAS: 1264-62-6

Applications Erythromycin Ethyl Succinate is a derivative of Erythromycin (E649950), an antibiotic.
References Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979); Serisier, D. et al.: J. Am. Med. Assoc., 309, 1206 (2013);

Formula: C₄₃H₇₅NO₁₆

Colore e forma: Off-White

Peso molecolare: 862.05

Ref: TR-E649985

Erythromycin Ethyl Succinate-13C,d3

Prodotto controllato

CAS: 1264-62-6

Applications Erythromycin Ethyl Succinate-13C,d3 is the deuterated form of Erythromycin Ethyl Succinate (E649985), which is a derivative of Erythromycin (E649950), an antibiotic.
References Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979); Serisier, D. et al.: J. Am. Med. Assoc., 309, 1206 (2013);

Formula: CC₄₂D₃H₇₂NO₁₆

Colore e forma: Neat

Peso molecolare: 866.064

Ref: TR-E649986

Erythromycin ethyl succinate

CAS: 1264-62-6

Erythromycin ethyl succinate is an ester prodrug that is formed by the reaction of erythromycin and ethylsuccinic acid. It has a broad spectrum of activity against Gram-positive and Gram-negative bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis. Erythromycin ethyl succinate is also active against Haemophilus influenzae, Moraxella catarrhalis, Chlamydia pneumoniae, Legionella pneumophila, Helicobacter pylori, Leptospira interrogans, Bordetella pertussis, Rickettsia rickettsii, Borrelia burgdorferi, Coxiella burnetii, and Mycoplasma pneumoniae. Erythromycin ethyl succinate has been shown to be effective in treating streptococcal pharyngitis and tissue infections.

Formula: C₄₃H₇₅NO₁₆

Purezza: Min. 95%

Peso molecolare: 862.05 g/mol

Ref: 3D-FE170906