CAS 12650-69-0
:Mupirocina
Descrizione:
Mupirocina è un antibiotico topico utilizzato principalmente per il trattamento delle infezioni cutanee causate da alcuni batteri, in particolare Staphylococcus aureus, comprese le ceppi resistenti alla meticillina (MRSA). È derivato dalla fermentazione del batterio Pseudomonas fluorescens. Mupirocina agisce inibendo la sintesi proteica batterica legandosi alla isoleucil-tRNA sintetasi, il che interrompe l'incorporazione dell'isoleucina nelle proteine, portando infine alla morte cellulare batterica. La sostanza è generalmente disponibile in forma di unguento o crema e viene applicata direttamente nell'area interessata. Mupirocina è noto per la sua bassa assorbimento sistemico quando usato topicamente, rendendolo efficace per infezioni localizzate con un rischio minimo di effetti collaterali sistemici. È generalmente ben tollerato, sebbene alcuni pazienti possano sperimentare irritazione locale o reazioni allergiche. A causa del suo specifico meccanismo d'azione e dell'efficacia contro ceppi resistenti, Mupirocina è un'opzione importante nella gestione delle infezioni cutanee ed è spesso utilizzato sia in contesti ambulatoriali che ospedalieri.
Formula:C26H44O9
InChI:InChI=1S/C26H44O9/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29)/b16-13+/t17-,18-,19-,20-,21-,24+,25-,26-/m0/s1
InChI key:InChIKey=MINDHVHHQZYEEK-HBBNESRFSA-N
SMILES:C([C@H]1[C@]([C@H]([C@H](C)O)C)(O1)[H])[C@@H]2[C@@H](O)[C@@H](O)[C@H](C/C(=C/C(OCCCCCCCCC(O)=O)=O)/C)OC2
Sinonimi:- (E)-(2S,3R,4R,5S)-5-((2S,3S,4S,5S)-2,3-Epoxy-5-hydroxy-4-methylhexyl)tetrahydro-3,4-dihydroxy-beta-methyl-2H-pyran-2-crotonic acid, ester with 9-hydroxynonanoic acid
- 8-Carboxyoctyl (E)-4-(2S,3R,4R,5S)-5-((2S,3S,4S,5S)-2,3-epoxy-5-hydroxy-4-methylhexyl)-3,4-dihydroxytetrahydro-2H-pyran-2-yl)-3-methylcrotonat
- 9-({(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-({(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl}methyl)tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoyl}oxy)nonanoic acid (non-preferred name)
- <span class="text-smallcaps">L</span>-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, (2E)-
- <span class="text-smallcaps">L</span>-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, [2E,8[2S,3S(1S,2S)]]-
- Bactoderm
- Bactroban
- Bactroban Ointment
- Brl 4910A
- Centany
- L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, (2E)-
- L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, [2E,8[2S,3S(1S,2S)]]-
- Mupirocin Neo-Sensitabs
- Mupirocin [USAN:INN:BAN]
- Mupirocina
- Mupirocina [Spanish]
- Mupirocine
- Mupirocine [French]
- Mupirocinum
- Mupirocinum [Latin]
- Mupricin
- Nonanoic acid, 9-((3-methyl-1-oxo-4-(tetrahydro-3,4-dihydroxy-5-((3-(2-hydroxy-1-methylpropyl)oxiranyl)methyl)-2H-pyran-2-yl)-2-butenyl)oxy)-, (2S-(2alpha(E),3beta,4beta,5alpha(2R*,3R*(1R*,2R*))))-
- Nonanoic acid, 9-[[(2Z)-3-methyl-1-oxo-4-[(2S,3R,4R,5S)-tetrahydro-3,4-dihydroxy-5-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]-2-oxiranyl]methyl]-2H-pyran-2-yl]-2-buten-1-yl]oxy]-
- Plasimine
- Pseudomonic acid
- Pseudomonic acid A
- Turixin
- Unii-D0Gx863Oa5
- Vedi altri sinonimi
Ordinare per
Purezza (%)
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100
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0
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50
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90
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95
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100
13 prodotti.
Mupirocin, 92%
CAS:<p>Mupirocin is involved in inhibition of protein synthesis was reversed by isoleucine and Pseudomonic Acid was shown to inhibit IleRS (isoleucyl-tRNA synthetase) in vitro. It also demonstrates weak inhibitory action on FARSL (phenylalanyl-tRNA synthetase). Efficacy against staphylococci and streptococ</p>Formula:C26H44O9Purezza:92%Peso molecolare:500.63L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, (2E)-
CAS:Formula:C26H44O9Purezza:98%Colore e forma:SolidPeso molecolare:500.6222Mupirocin
CAS:<p>Mupirocin (BRL-4910A) is a RNA synthetase inhibitor antibacterial. It has shown excellent activity against gram-positive staphylococci and streptococci.</p>Formula:C26H44O9Purezza:97.37% - 97.46%Colore e forma:SolidPeso molecolare:500.62Mupirocin
CAS:Formula:C26H44O9Purezza:920 - 1020 μg/mg (anhydrous)Colore e forma:White to off-white powderPeso molecolare:500.63Mupirocin
CAS:Formula:C26H44O9Purezza:>98.0%(T)Colore e forma:White to Almost white powder to crystalPeso molecolare:500.63Mupirocin
CAS:Prodotto controllato<p>Applications Mupirocin, is a major component of the pseudomonic acid, an antibiotic complex produced by Pseudomonas fluorescens NCIB 10586. Topical antibacterial.<br>References Hughes, J., et al.: J. Antibiot., 31, 330 (1978), Ward, A., et al.: Drugs, 32, 425 (1986), Casewell, M.W., et al.: J. Antimicrob. Chemother., 19, 1 (1987),<br></p>Formula:C26H44O9Colore e forma:White To Off-WhitePeso molecolare:500.62Ref: ST-EA-CP-M50000
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaMupirocin
CAS:<p>Inhibitor of isoleucyl-tRNA synthetase; inhibitor of protein synthesis</p>Formula:C26H44O9Purezza:Min. 92 Area-%Colore e forma:White PowderPeso molecolare:500.62 g/mol
