CAS 126766-32-3

metile 4-[(3,4-diclorofenil)acetil]-3-(pirrolidin-1-ilmetil)piperazina-1-carbossilato (2E)-but-2-enedioato

Descrizione:

metile 4-[(3,4-diclorofenil)acetil]-3-(pirrolidin-1-ilmetil)piperazina-1-carbossilato (2E)-but-2-enedioato, identificato dal numero CAS 126766-32-3, è un composto organico sintetico caratterizzato dalla sua complessa struttura molecolare, che include un anello di piperazina, un gruppo di pirrolidina e un gruppo diclorofenile. Questo composto tipicamente mostra proprietà associate ai suoi gruppi funzionali, come la potenziale solubilità in solventi organici e una stabilità moderata in condizioni standard. La presenza degli anelli di piperazina e pirrolidina suggerisce una possibile attività biologica, rendendolo di interesse nella chimica medicinale, in particolare nello sviluppo di farmaci. La sua struttura indica potenziali interazioni con bersagli biologici, che possono portare a vari effetti farmacologici. Inoltre, la sintesi del composto implica più fasi, evidenziando la sua complessità e la necessità di un'attenta manipolazione in ambienti di laboratorio. Come molti composti sintetici, i dati di sicurezza e le precauzioni di manipolazione sono essenziali a causa della potenziale tossicità o reattività.

Formula: C₁₉H₂₅Cl₂N₃O₃·C₄H₄O₄

InChI: InChI=1S/C19H25Cl2N3O3.C4H4O4/c1-27-19(26)23-8-9-24(15(13-23)12-22-6-2-3-7-22)18(25)11-14-4-5-16(20)17(21)10-14;5-3(6)1-2-4(7)8/h4-5,10,15H,2-3,6-9,11-13H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

InChI key: InChIKey=ABTNETSDXZBJTE-WLHGVMLRSA-N

SMILES: C(CC1=CC(Cl)=C(Cl)C=C1)(=O)N2C(CN3CCCC3)CN(C(OC)=O)CC2.C(=C/C(O)=O)\C(O)=O

Sinonimi:

• 1-Piperazinecarboxylic acid, 4-[(3,4-dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-, methyl ester, (2E)-2-butenedioate (1:1)
• 1-Piperazinecarboxylic acid, 4-[(3,4-dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-, methyl ester, (E)-2-butenedioate (1:1)
• 1-Piperazinecarboxylic acid, 4-[2-(3,4-dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-, methyl ester, (2E)-2-butenedioate (1:1)
• Gr 89696
• Methyl 4-[(3,4-dichlorophenyl)acetyl]-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate (2E)-but-2-enedioate (1:1)
• 4-([3,4-DICHLOROPHENYL]ACETYL)-3-(1-PYRROLIDINYLMETHYL)-1-PIPERAZINECARBOXYLIC ACID METHYL ESTER FUMARATE
• GR 89696 fumarate salt solid
• 4-((3,4-Dichlorophenyl)acetyl)-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylicacidmethylesterfumarate
• Methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate
• GR 89696 FUMARATE

1-Piperazinecarboxylic acid, 4-[2-(3,4-dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-, methyl ester, (2E)-2-butenedioate (1:1)

CAS: 126766-32-3

Formula: C₂₃H₂₉Cl₂N₃O₇

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 530.3983

Ref: IN-DA000T7X

Methyl 4-(2-(3,4-Dichlorophenyl)Acetyl)-3-(Pyrrolidin-1-Ylmethyl)Piperazine-1-Carboxylate Fumarate

CAS: 126766-32-3

Methyl 4-(2-(3,4-Dichlorophenyl)Acetyl)-3-(Pyrrolidin-1-Ylmethyl)Piperazine-1-Carboxylate Fumarate

Purezza: 98%

Peso molecolare: 530.4g/mol

Ref: 54-OR1023356

GR 89696 fumarate

CAS: 126766-32-3

GR 89696 fumarate

Purezza: ≥98%

Peso molecolare: 530.4g/mol

Ref: 54-BUP10447

GR 89696 fumarate salt

CAS: 126766-32-3

Formula: C₁₉H₂₅Cl₂N₃O₃·C₄H₄O₄

Peso molecolare: 530.40

Ref: 7W-GK9421

GR 89696

Prodotto controllato

CAS: 126766-32-3

Formula: C₁₉H₂₅Cl₂N₃O₃·C₄H₄O₄

Colore e forma: Neat

Peso molecolare: 530.398

Ref: TR-G779535

GR 89696 fumarate salt

CAS: 126766-32-3

GR 89696 is a kappa-opioid receptor agonist that is a racemic mixture of the two enantiomers, S and R. It has high affinity for the human kappa-opioid receptor, with values of 500 nM and 100 nM for the S and R enantiomers, respectively. GR 89696 has been shown to produce antinociception in experimental animals. This effect was blocked by pretreatment with the δ-opioid antagonist naltrindole, but not by pretreatment with the κ-opioid antagonist norbinaltorphimine or the κ/δ-opioid antagonist pentazocine. The drug also inhibits rotarod performance in mice at low doses, which may be due to its sedative effect.
GR 89696 has been shown to inhibit bone cancer cell growth in vitro and in vivo without inducing significant toxicity in healthy cells. The drug also showed efficacy against

Formula: C₁₉H₂₅Cl₂N₃O₃·C₄H₄O₄

Purezza: Min. 95%

Peso molecolare: 530.4 g/mol

Ref: 3D-BFA76632

GR 89696 fumarate

CAS: 126766-32-3

GR 89696 fumarate is a highly selective κ2 opioid receptor agonist (IC50 = 0.04nM) with anti-pruritchy, anti-injury and neuroprotective effects.

Formula: C₂₃H₂₉Cl₂N₃O₇

Purezza: 99.84%

Colore e forma: Solid

Peso molecolare: 530.4

Ref: TM-T22810