CAS 127045-41-4

Pazufloxacina

Descrizione:

Pazufloxacina è un antibiotico fluoroquinolone sintetico caratterizzato dalla sua attività antibatterica ad ampio spettro, in particolare contro batteri Gram-negativi e alcuni Gram-positivi. Funziona inibendo la girasi del DNA batterico e la topoisomerasi IV, enzimi essenziali per la replicazione e trascrizione del DNA. Pazufloxacina è noto per le sue favorevoli proprietà farmacocinetiche, inclusa una buona biodisponibilità orale e penetrazione nei tessuti, che migliorano la sua efficacia terapeutica. Il composto viene tipicamente somministrato in contesti clinici per trattare varie infezioni, comprese le infezioni respiratorie e del tratto urinario. La sua struttura chimica presenta un nucleo biciclico con un atomo di fluoro, che contribuisce alla sua potenza e resistenza a certi meccanismi di efflusso batterico. Sebbene Pazufloxacina abbia dimostrato efficacia negli studi clinici, il suo uso può essere limitato da potenziali effetti collaterali, inclusi disturbi gastrointestinali e, in rari casi, reazioni più gravi. Come con altri antibiotici, l'emergere di resistenza è una preoccupazione, richiedendo una considerazione attenta del suo uso nei regimi di trattamento.

Formula: C₁₆H₁₅FN₂O₄

InChI: InChI=1S/C16H15FN2O4/c1-7-6-23-14-11(16(18)2-3-16)10(17)4-8-12(14)19(7)5-9(13(8)20)15(21)22/h4-5,7H,2-3,6,18H2,1H3,(H,21,22)/t7-/m0/s1

InChI key: InChIKey=XAGMUUZPGZWTRP-ZETCQYMHSA-N

SMILES: O=C1C=2C3=C(C(=C(F)C2)C4(N)CC4)OC[C@H](C)N3C=C1C(O)=O

Sinonimi:

• (-)-(3S)-10-(1-Aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
• (3S)-10-(1-aminocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
• (3s)-10-(1-aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7h-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid C16H15FN2O4
• 10-(1-aminocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 10-(1-aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (3S)-
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 10-(1-aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (R)-
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 10-(1-aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (S)-
• Pazufloxaxin
• T 3761

Pazufloxacin Mesylate

CAS: 127045-41-4, 163680-77-1

Formula: C₁₆H₁₅FN₂O₄·CH₄O₃S

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Orange to Green powder to crystal

Peso molecolare: 414.40

Ref: 3B-P1962

(2S)-6-(1-aminocyclopropyl)-7-fluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.0,5,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid

CAS: 127045-41-4

Formula: C₁₆H₁₅FN₂O₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 318.2997

Ref: IN-DA01DQAI

Pazufloxacin

CAS: 127045-41-4

Pazufloxacin (T-3761) is a broad-spectrum fluoroquinolone antibiotic effective against various infections, including strains resistant to other quinolones.

Formula: C₁₆H₁₅FN₂O₄

Colore e forma: Solid

Peso molecolare: 318.3

Ref: TM-T75296

Pazufloxacin

CAS: 127045-41-4

Formula: C₁₆H₁₅FN₂O₄

Purezza: ≥ 98.0%

Colore e forma: White to light yellow or beige crystalline powder

Peso molecolare: 318.30

Ref: 7W-GA3636

Pazufloxacin 100 µg/mL in Acetonitrile

CAS: 127045-41-4

Formula: C₁₆H₁₅FN₂O₄

Colore e forma: Single Solution

Peso molecolare: 318.30

Ref: 04-A15896300AL-100

Pazufloxacin

CAS: 127045-41-4

Formula: C₁₆H₁₅FN₂O₄

Colore e forma: Neat

Peso molecolare: 318.30

Ref: 04-C15896300

Pazufloxacin

Prodotto controllato

CAS: 127045-41-4

Applications Pazufloxacin (CAS# 127045-41-4) is a useful research chemical compound.

Formula: C₁₆H₁₅FN₂O₄

Colore e forma: Off-White To Light Yellow

Peso molecolare: 318.30

Ref: TR-P212720

Pazufloxacin

CAS: 127045-41-4

Pazufloxacin is an antibacterial agent, which is a synthetic derivative originating from the fluoroquinolone class of compounds. This source categorizes it alongside a group of broad-spectrum antibiotics known for their efficacy against a wide variety of bacterial pathogens. The mode of action of pazufloxacin involves the inhibition of bacterial DNA gyrase and topoisomerase IV. These are essential enzymes for bacterial DNA replication, transcription, repair, and recombination processes. By inhibiting these enzymes, pazufloxacin disrupts the bacterial DNA processes, ultimately leading to cell death.

Formula: C₁₆H₁₅FN₂O₄

Purezza: Min. 95%

Peso molecolare: 318.3 g/mol

Ref: 3D-AP65124