CAS 127060-75-7

N~6~-{N~2~-[(benzyloxi)carbonil]-N~5~-(diaminometilidene)-L-ornitil}-N~2~-[N-(piridin-3-ilcarbonil)-L-tirosil]-L-lisil-L-istidil-L-prolil-L-isoleucina

Descrizione:

La sostanza chimica con il nome "N~6~-{N~2~-[(benzyloxi)carbonil]-N~5~-(diaminometilidene)-L-ornitil}-N~2~-[N-(piridin-3-ilcarbonil)-L-tirosil]-L-lisil-L-istidil-L-prolil-L-isoleucina" e numero CAS 127060-75-7 è un derivato peptidico complesso. Presenta più residui di amminoacidi, tra cui ornitina, lisina, istidina, prolina e isoleucina, che contribuiscono alle sue proprietà strutturali e funzionali. La presenza di gruppi benzyloxycarbonile e piridin-3-ilcarbonile indica che è stata modificata per migliorare la stabilità o la bioattività. Questo composto può mostrare specifiche attività biologiche, potenzialmente correlate alle sue interazioni con recettori biologici o enzimi, rendendolo di interesse nella ricerca farmaceutica. La sua struttura intricata suggerisce potenziali applicazioni nella progettazione di farmaci, in particolare nel mirare a specifici percorsi o condizioni. Tuttavia, sarebbero necessari studi dettagliati per chiarire completamente le sue proprietà farmacologiche e i meccanismi d'azione. Come molti peptidi, la sua solubilità, stabilità e reattività possono variare in base alle condizioni ambientali e alle modifiche.

Formula: C₅₂H₆₉N₁₃O₁₁

InChI: InChI=1/C52H69N13O11/c1-3-32(2)43(50(73)74)64-48(71)42-17-11-25-65(42)49(72)41(27-36-29-56-31-59-36)62-46(69)39(60-47(70)40(26-33-18-20-37(66)21-19-33)61-44(67)35-14-9-22-55-28-35)15-7-8-23-57-45(68)38(16-10-24-58-51(53)54)63-52(75)76-30-34-12-5-4-6-13-34/h4-6,9,12-14,18-22,28-29,31-32,38-43,66H,3,7-8,10-11,15-17,23-27,30H2,1-2H3,(H,56,59)(H,57,68)(H,60,70)(H,61,67)(H,62,69)(H,63,75)(H,64,71)(H,73,74)(H4,53,54,58)/t32-,38-,39-,40-,41-,42-,43-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=O)O)N=C([C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)N=C([C@H](CCCCN=C([C@H](CCCNC(=N)N)N=C(O)OCc1ccccc1)O)N=C([C@H](Cc1ccc(cc1)O)N=C(c1cccnc1)O)O)O)O

Angiotensin II Receptor Ligand

CAS: 127060-75-7

Depending on concentrations, CGP-42112 acts as a selective agonist or antagonist of AT₂ receptor-mediated effects.

Formula: C₅₂H₆₉N₁₃O₁₁

Purezza: 98.2%

Colore e forma: Yellowish Powder

Peso molecolare: 1052.2

Ref: 01-4015751

CGP 42112

CAS: 127060-75-7

Formula: C₅₂H₆₉N₁₃O₁₁

Purezza: 98%

Peso molecolare: 1052.1848

Ref: IN-DA009ADU

(2S,3S)-2-((S)-1-((5S,12S,15S)-15-((1H-Imidazol-5-yl)methyl)-5-(3-guanidinopropyl)-12-((S)-3-(4-hydroxyphenyl)-2-(nicotinamido)propanamido)-3,6,13-trioxo-1-phenyl-2-oxa-4,7,14-triazahexadecan-16-oyl)p

CAS: 127060-75-7

(2S,3S)-2-((S)-1-((5S,12S,15S)-15-((1H-Imidazol-5-yl)methyl)-5-(3-guanidinopropyl)-12-((S)-3-(4-hydroxyphenyl)-2-(nicotinamido)propanamido)-3,6,13-trioxo-1-phenyl-2-oxa-4,7,14-triazahexadecan-16-oyl)p

Purezza: 98%

Peso molecolare: 1052.2g/mol

Ref: 54-OR1062962

CGP-42112A

CAS: 127060-75-7

Formula: C₅₂H₆₉N₁₃O₁₁

Peso molecolare: 1052.18

Ref: 7W-GK1642

CGP-42112

CAS: 127060-75-7

CGP-42112 is an agonist of the Angiotensin-II subtype 2 receptor (AT2 R).

Formula: C₅₂H₆₉N₁₃O₁₁

Colore e forma: White Solid

Peso molecolare: 1052.18

Ref: TM-T14939

CGP 42112

CAS: 127060-75-7

CGP 42112 is a peptide that inhibits the binding of ligands to their receptors. It has been shown to be an effective inhibitor of protein interactions and has been used in research tools for the study of protein-protein interactions. CGP 42112 is an activator of the Ligand-gated ion channels and can be used as an antibody for receptor detection. This compound has a high purity with a CAS number 127060-75-7.

Formula: C₅₂H₆₉N₁₃O₁₁

Purezza: Min. 95%

Peso molecolare: 1,052.2 g/mol

Ref: 3D-PAN-4296-V

Angiotensin II Receptor Ligand Nicotinoyl-Tyr-Lys(Z-Arg)-His-Pro-Ile-OH

CAS: 127060-75-7

Angiotensin II receptor ligand nicotinoyl-tyrosine-arginine-proline-ile (ANGII) is a peptide that acts as a potent angiotensin II receptor agonist. It can be used to anesthetize rats and cause bradykinin b2 receptor activation. ANGII has been shown to inhibit the growth of several types of tumors, such as human melanoma cells, in animal experiments. This drug also has antiangiogenic properties, which may be due to its ability to induce the production of tumor necrosis factor-α (TNF-α).

Formula: C₅₂H₆₉N₁₃O₁₁

Purezza: Min. 95%

Peso molecolare: 1,052.19 g/mol

Ref: 3D-FA110425