CAS 127191-97-3

4-[(2S)-2-[(5-Isochinolinilsulfonil)metilamino]-3-osso-3-(4-fenil-1-piperazinil)propil]fenil 5-isochinolinsulfonato

Descrizione:

La sostanza chimica nota come "4-[(2S)-2-[(5-Isochinolinilsulfonil)metilamino]-3-osso-3-(4-fenil-1-piperazinil)propil]fenil 5-isochinolinsulfonato," con il numero CAS 127191-97-3, è un composto organico complesso caratterizzato dalla sua struttura multifunzionale. Presenta un moiety di isoquinolina, nota per la sua attività biologica, in particolare in farmacologia. La presenza di un gruppo sulfonato suggerisce una potenziale solubilità in ambienti acquosi, migliorando la sua biodisponibilità. Il composto contiene anche un anello di piperazina, spesso associato a varie proprietà farmacologiche, inclusi effetti ansiolitici e antidepressivi. La sua estereoquimica, indicata dalla configurazione (2S), implica disposizioni spaziali specifiche che possono influenzare la sua interazione con obiettivi biologici. In generale, questo composto è probabilmente di interesse nella chimica medicinale, in particolare nello sviluppo di agenti terapeutici mirati a disturbi neurologici o psichiatrici, date le sue componenti strutturali comunemente associate a tali attività.

Formula: C₃₈H₃₅N₅O₆S₂

InChI: InChI=1S/C38H35N5O6S2/c1-41(50(45,46)36-11-5-7-29-26-39-19-17-33(29)36)35(38(44)43-23-21-42(22-24-43)31-9-3-2-4-10-31)25-28-13-15-32(16-14-28)49-51(47,48)37-12-6-8-30-27-40-20-18-34(30)37/h2-20,26-27,35H,21-25H2,1H3/t35-/m0/s1

InChI key: InChIKey=RJVLFQBBRSMWHX-DHUJRADRSA-N

SMILES: S(N([C@H](C(=O)N1CCN(CC1)C2=CC=CC=C2)CC3=CC=C(OS(=O)(=O)C=4C5=C(C=CC4)C=NC=C5)C=C3)C)(=O)(=O)C=6C7=C(C=CC6)C=NC=C7

Sinonimi:

• (S)-4-(2-(N-methylisoquinoline-5-sulfonamido)-3-oxo-3-(4-phenylpiperazin-1-yl)propyl)phenyl isoquinoline-5-sulfonate
• (S)-5-Isoquinolinesulfonic Acid 4-(2-[(5-Isoquinolinylsulfonyl)Methylamino]- 3-Oxo-3-[4-Phenyl-1-Piperazinyl]Propyl)Phenyl Ester
• 1-[N,O-Bis-(5-Isoquinolinesulfonyl)-N-Methyl-L-Tyrosyl]-4-Phenylpiperazine
• 4-((2s)-2-((5-Isoquinolinylsulfonyl)Methylamino)-3-Oxo-3-(4-Phenyl-1-Piperazinyl)Propyl)Phenylisoquinolinesulfonicacid
• 4-[(2S)-2-[(5-Isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl 5-isoquinolinesulfonate
• 4-[(2S)-2-[(isoquinolin-5-ylsulfonyl)(methyl)amino]-3-oxo-3-(4-phenylpiperazin-1-yl)propyl]phenyl isoquinoline-5-sulfonate
• 4-{2-[(Isoquinolin-5-Ylsulfonyl)(Methyl)Amino]-3-Oxo-3-(4-Phenylpiperazin-1-Yl)Propyl}Phenyl Isoquinoline-5-Sulfonate
• 5-Isoquinolinesulfonic acid, 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester
• 5-Isoquinolinesulfonic acid, 4-[2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester, (S)-
• Kn-62

KN-62

CAS: 127191-97-3

Potently and specifically inhibits calcium/calmodulin kinase II

Formula: C₃₈H₃₅N₅O₆S₂

Colore e forma: Powder

Peso molecolare: 721.84

Ref: 02-J62444

5-Isoquinolinesulfonic acid, 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester

CAS: 127191-97-3

Formula: C₃₈H₃₅N₅O₆S₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 721.8444

Ref: IN-DA000WQW

(S)-4-(2-(N-Methylisoquinoline-5-Sulfonamido)-3-Oxo-3-(4-Phenylpiperazin-1-Yl)Propyl)Phenyl Isoquinoline-5-Sulfonate

CAS: 127191-97-3

(S)-4-(2-(N-Methylisoquinoline-5-Sulfonamido)-3-Oxo-3-(4-Phenylpiperazin-1-Yl)Propyl)Phenyl Isoquinoline-5-Sulfonate

Purezza: 99%

Peso molecolare: 721.84g/mol

Ref: 54-OR1023208

KN-62

CAS: 127191-97-3

Formula: C₃₈H₃₅N₅O₆S₂

Peso molecolare: 721.84

Ref: 7W-GK6974

KN-62

CAS: 127191-97-3

KN-62

Purezza: ≥98%

Peso molecolare: 721.84g/mol

Ref: 54-BUP03323

KN-62

CAS: 127191-97-3

KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.

Formula: C₃₈H₃₅N₅O₆S₂

Purezza: 99.80% - >99.99%

Colore e forma: White Solid

Peso molecolare: 721.84

Ref: TM-T2694

KN 62

Prodotto controllato

CAS: 127191-97-3

Inhibitor of calcium/calmodulin-dependent protein kinase II

Formula: C₃₈H₃₅N₅O₆S₂

Purezza: Min. 95%

Colore e forma: White To Off-White To Yellow Solid

Peso molecolare: 721.85 g/mol

Ref: 3D-FB24811