CAS 12771-72-1

verruculogeno da penicillium verruculosum

Descrizione:

La verruculogen è una micotossina prodotta dal fungo Penicillium verruculosum, classificata nella categoria degli alcaloidi indolici. Questo composto è caratterizzato dalla sua struttura complessa, che include un telaio biciclico e più gruppi funzionali, contribuendo alla sua attività biologica. La verruculogen presenta proprietà neurotossiche, influenzando il rilascio di neurotrasmettitori e potenzialmente portando a effetti avversi sul sistema nervoso. È stata studiata per le sue potenziali implicazioni nella sicurezza alimentare, poiché può contaminare vari prodotti agricoli. Il composto è anche di interesse nella ricerca farmacologica grazie al suo meccanismo d'azione unico e alle potenziali applicazioni terapeutiche. Tuttavia, la sua tossicità richiede un'attenta gestione e regolamentazione. In termini di solubilità, la verruculogen è tipicamente solubile in solventi organici, il che è comune per molte micotossine. In generale, sebbene la verruculogen presenti vie intriganti per la ricerca, il suo profilo tossicologico sottolinea l'importanza di monitorare e controllare la sua presenza nei prodotti alimentari e nei mangimi.

Formula: C₂₇H₃₃N₃O₇

InChI: InChI=1S/C27H33N3O7/c1-14(2)11-20-29-18-12-15(35-5)8-9-16(18)21-22(29)19(13-26(3,4)37-36-20)30-24(32)17-7-6-10-28(17)25(33)27(30,34)23(21)31/h8-9,11-12,17,19-20,23,31,34H,6-7,10,13H2,1-5H3/t17-,19-,20+,23-,27+/m0/s1

InChI key: InChIKey=LRXYHMMJJCTUMY-GWXUGYLUSA-N

SMILES: C(=C(C)C)[C@@H]1N2C3=C(C=4C2=CC(OC)=CC4)[C@H](O)[C@]5(O)N([C@]3(CC(C)(C)OO1)[H])C(=O)[C@]6(N(C5=O)CCC6)[H]

Sinonimi:

• (5R,10S,10aR,14aS,15bS)-1,10,10a,14,14a,15b-Hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propen-1-yl)-5H,12H-3,4-dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione
• 10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methylprop-1-en-1-yl)-1,10,10a,14,14a,15b-hexahydro-12H-3,4-dioxa-5a,11a,15a-triazacycloocta[1,2,3-lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione
• 5H,12H-3,4-Dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione, 1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propen-1-yl)-, (5R,10S,10aR,14aS,15bS)-
• 5H,12H-3,4-Dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione, 1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-, (5R,10S,10aR,14aS,15bS)-
• 5H,12H-3,4-Dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione, 1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-, [5R-(5α,10α,10aα,14aα,15bα)]-
• Na 209A
• TR 1 toxin
• Verruculogen
• Verruculogen TR 1
• Verruculogen, Penicillium verruculosum
• GWIWVUJHTCZBOP-FCXIIMTCSA-N
• tr1
• (5R)-1,10,10a,14,14aα,15bα-Hexahydro-10α,10aα-dihydroxy-7-methoxy-2,2-dimethyl-5α-(2-methyl-1-propenyl)-12H-3,4-dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione
• Taste receptor type 1 member 1
• VERRUCULOGEN FROM PENICILLIUM VERRUCULOS
• verruculogen from penicillium*verruculosum
• Verruculogen NA 209A TR 1 toxin
• ANTI-TAS1R1 (CENTER) antibody produced in rabbit
• TRXR1
• TAS1R1
• MGC9145
• Verruculogen solution
• (5R)-2,5,10,10a,11,12,13,14,14aα,15bα-Decahydro-10α,10aα-dihydroxy-7-methoxy-2,2-dimethyl-5α-(2-methyl-1-propenyl)-3,4-dioxa-5a,11a,15a-triaza-1H-cyclooct[lm]indeno[5,6-b]fluorene-11,15-dione
• (5R-(5alpha,10 alpha,10Aalpha,14aalpha,15balpha))-1,10,10A,14,14A,15B-hexahydro-10,10A-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-5H,12H-3,4-dioxa-5A,11A,15A-triaza cyclooct (1m) indeno (5,6-B)fluorene-11,15(2H,13H)-dione
• TR-1TOXIN
• verruculogentr1
• 5H,12H-3,4-Dioxa-5A,11A,15A-triazacyclooct(lm)indeno(5,6-B)fluorene-11,15(2H,13H)-dione, 1,10,10A,14,14A,15B-hexahydro-10,10A-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-,(5R-(5-alpha,10-alpha,10A-alpha,14A-alpha-15B-alpha))-
• GPR70
• yl-5-(2-methyl-1-propenyl)-,(5r-(5-alpha,10-alpha,10a-alpha,14a-alpha-15b-alp
• GRIM-12
• Anti-TAS1R1 (N-terminal) antibody produced in rabbit
• 3h)-dione,1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimeth
• T1R1
• 5h,12h-3,4-dioxa-5a,11a,15a-triazacyclooct(lm)indeno(5,6-b)fluorene-11,15(2h,1
• VERRUCOLOGEN
• Anti-TAS1R1 (C-terminal) antibody produced in rabbit
• TXNRD1 human

Verruculogen

CAS: 12771-72-1

Formula: C₂₇H₃₃N₃O₇

Purezza: 98.89%

Colore e forma: Brownish. Amorphous solid

Peso molecolare: 511.0

Ref: 8R-AD0189

5H,12H-3,4-Dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione,1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-, (5R,10S,10aR,14aS,15bS)-

CAS: 12771-72-1

Formula: C₂₇H₃₃N₃O₇

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 511.5668

Ref: IN-DA00VQYN

Verruculogen from Penicillium verruculosum

CAS: 12771-72-1

Verruculogen from Penicillium verruculosum

Formula: C₂₇H₃₅N₃O₇

Purezza: By hplc: 97.52% (Typical Value in Batch COA)

Colore e forma: white powder

Peso molecolare: 513.58g/mol

Ref: 54-BIV1002

Verruculogen

CAS: 12771-72-1

Verruculogen, a toxin from Penicillium/Aspergillus, blocks Ca2+-K+ channels and halts mammalian M phase.

Formula: C₂₇H₃₃N₃O₇

Purezza: 98%

Colore e forma: White Powder

Peso molecolare: 511.57

Ref: TM-T13297

Verruculogen

CAS: 12771-72-1

Formula: C₂₇H₃₃N₃O₇

Purezza: ≥ 95.0%

Colore e forma: Off-white to brown solid

Peso molecolare: 511.6

Ref: 7W-GL5203

Verruculogen

CAS: 12771-72-1

Applications Verruculogen is a mycotoxin and novel mammalian cell cycle inhibitors produced by Aspergillus fumigatus.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cui, C. et al.: Jour. of Ant., 49(6), 527-533, (1996)

Formula: C₂₇H₃₃N₃O₇

Colore e forma: Neat

Peso molecolare: 511.57

Ref: TR-V267190

Verruculogen

CAS: 12771-72-1

Verruculogen is a mycotoxin, which is derived from certain species of fungi, primarily those in the genera Aspergillus and Penicillium. It is synthesized by these fungi during their secondary metabolic processes. As a chemical compound, verruculogen acts by inhibiting calcium channels in nerve cells, disrupts neurotransmitter release, and affects neuronal activity. This mode of action is crucial in understanding its role in toxicology and pharmacology.

Purezza: Min. 95%

Ref: 3D-BV162751