CAS 128-13-2

Acido ursodesossicolico

Descrizione:

Acido ursodesossicolico (UDCA), con il numero CAS 128-13-2, è un acido biliare che si trova naturalmente nel corpo, sintetizzato principalmente dal colesterolo. È caratterizzato dalle sue proprietà idrofili, che lo rendono meno tossico rispetto ad altri acidi biliari. L'UDCA è noto per la sua capacità di promuovere la solubilizzazione del colesterolo nella bile, contribuendo così a prevenire la formazione di calcoli biliari di colesterolo. È stato utilizzato terapeuticamente per trattare varie malattie epatiche, tra cui la colangite biliare primaria e alcune forme di colestasi. Il composto presenta una struttura unica, con un gruppo idrossile in posizione 7, che contribuisce alla sua solubilità e attività biologica. Inoltre, l'UDCA ha effetti anti-infiammatori e immunomodulatori, rendendolo utile nella gestione delle condizioni epatiche. Il suo meccanismo d'azione implica il miglioramento del flusso biliare e la riduzione della tossicità degli acidi biliari, il che può essere particolarmente vantaggioso in caso di disfunzione epatica. In generale, Acido ursodesossicolico è un composto significativo sia in contesti clinici che biochimici, riflettendo la sua importanza nella salute gastrointestinale e nella gestione delle malattie.

Formula: C₂₄H₄₀O₄

InChI: InChI=1/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/p-1/t14-,15-,16-,17-,18+,19+,20+,22+,23+,24-/m1/s1

InChI key: InChIKey=RUDATBOHQWOJDD-UZVSRGJWSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@@H]3O)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]

Sinonimi:

• (3α,5β,7β)-3,7-Dihydroxycholan-24-oic acid
• 17β-(1-Methyl-3-carboxypropyl)etiocholane-3α,7β-diol
• 3α,7β-Dihydroxy-5β-cholan-24-oate
• 3α,7β-Dihydroxy-5β-cholan-24-oic acid
• 3α,7β-Dihydroxy-5β-cholanic acid
• 3α,7β-Dihydroxy-5β-cholanoic acid
• 3α,7β-Dihydroxycholanic acid
• 5β-Cholan-24-oic acid, 3α,7β-dihydroxy-
• 5β-Cholanic acid, 3α,7β-dihydroxy-
• 7β-Hydroxylithocholic acid
• Acide Ursodesoxycholique
• Acido Ursodeoxicolico
• Actigall
• Adursal
• Arsacol
• CHOLON-24-OIC ACID, 3,7-DIHYDROXY-(3α, 5β, 7.β)-
• Cholit-Ursan
• Delursan
• Desocol
• Desol
• Destolit
• Deursil
• Litursol
• Lyeton
• Nsc 683769
• Paptarom
• Solutrat
• Udca
• Urdes
• Urosiol
• Ursacol
• Ursic acid
• Urso
• Ursobilin
• Ursochol
• Ursocholic acid, deoxy-
• Ursocol
• Ursodamor
• Ursodeoxycholic Acid
• Ursodeoxycholsaure
• Ursodesoxycholic acid
• Ursodiol
• Ursofalk
• Ursogall
• Ursolvan
• Ursosan
• (4R)-4-[(3R,5S,7S,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• (3alpha,5beta,7beta)-3,7-dihydroxycholan-24-oic acid
• 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethanol
• (4R)-4-[(3R,5S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• (3alpha,5alpha,7beta)-3,7-dihydroxycholan-24-oate
• (3alpha,5beta,7beta)-3,7-dihydroxycholan-24-oate
• 3alpha,7beta-Dihydroxy-6beta-cholan-24-oic acid
• (3alpha,5beta,7beta,8xi,9xi,14xi)-3,7-dihydroxycholan-24-oic acid
• Cholan-24-oic acid, 3,7-dihydroxy-, (3α,5β,7β)-
• (3alpha,5beta,7alpha)-3,7-dihydroxycholan-24-oic acid
• 3,7-Dihydroxycholan-24-oic acid
• 5BETA-CHOLANIC ACID-3ALPHA,7BETA-DIOL
• 3,7-dihydroxy-,(3-alpha,5-beta,7-beta)-cholan-24-oicaci
• 17-beta-(1-methyl-3-carboxypropyl)etiocholane-3-alpha,7-beta-diol
• 3ALPHA, 7BETA-DIOXYCHOLANIC ACID
• 5BETA-CHOLAN-24-OIC ACID-3ALPHA, 7BETA-DIOL
• (6-BETA)-CHOLANIC ACID-(3-ALPHA)-(7-BETA)-DIOL
• UDCS
• 6BETA-CHOLANIC ACID-3A,7BETA-DIOL
• 3ALPHA, 7BETA-DIHYDROXY-5BETA-CHOLANIC ACID
• 3ALPHA,7BETA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID
• 7BETA-HYDROXYLITHOCHOLIC ACID
• 3-alpha,7-beta-dihydroxy-5-beta-cholan-24-oicaci

Ursodeoxycholic acid

Prodotto controllato

CAS: 128-13-2

Ursodeoxycholic acid is a secondary bile acid, which is derived from the metabolism of primary bile acids by intestinal bacteria. It modifies the composition of bile and reduces the absorption of cholesterol in the gastrointestinal tract by decreasing the cholesterol saturation of bile. This leads to a solubilization of cholesterol gallstones, making it an essential therapeutic agent in the management of cholesterol gallstone disease.

Formula: C₂₄H₄₀O₄

Colore e forma: Powder

Peso molecolare: 392.57 g/mol

Ref: 3D-FU09676

Ursodeoxycholic acid

Prodotto controllato

CAS: 128-13-2

Ursodeoxycholic acid is a naturally occurring bile acid, which is synthesized in the liver from cholesterol. It functions primarily to reduce cholesterol absorption in the intestine and dissolve cholesterol gallstones. This mechanism involves changing the composition of bile and reducing the cholesterol saturation in bile, which reduces micellar cholesterol and bile acid pool size, limiting stone formation.

Formula: C₂₄H₄₀O₄

Purezza: Min. 98 Area-%

Peso molecolare: 392.58 g/mol

Ref: 3D-U-9000

Ursodeoxycholic acid

CAS: 128-13-2

Ref: BE-RMT20080-1G

Ursodeocycholic Acid-3-Sulfate Sodium Salt

CAS: 128-13-2

Ref: BE-MU-1038

Ursodeoxycholic acid

CAS: 128-13-2

Ref: BE-RMT20080

Ursodeoxycholic Acid-[13C3] in Methanol

CAS: 128-13-2

Methanol

Ref: BE-MC-1006XM-100

Ursodeoxycholic Acid in Methanol

CAS: 128-13-2

Methanol

Ref: BE-MU-1006YM-1000

Ursodeoxycholic Acid

CAS: 128-13-2

(R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Formula: C₂₄H₄₀O₄

Purezza: 98%

Peso molecolare: 392.57

Ref: IN-DG17928

Ursodeoxycholic Acid (UDCS) extrapure, 99%

CAS: 128-13-2

Formula: C₂₄H₄₀O₄

Purezza: min. 99.5%

Colore e forma: White to off-white, Crystalline powder, Clear, Colourless to pale yellow

Peso molecolare: 392.57

Ref: SR-50178