CAS 128-53-0

N-etilmaleimmide

Descrizione:

N-etilmaleimmide è un composto organico caratterizzato dalla sua struttura di maleimide, che presenta un anello a cinque membri contenente un gruppo carbonile e un atomo di azoto. È un liquido incolore o giallo pallido a temperatura ambiente, con un odore distintivo. Questo composto è noto per la sua reattività, in particolare nella formazione di legami covalenti con nucleofili, rendendolo un reagente prezioso nella sintesi organica e nella biochimica. N-etilmaleimmide è spesso utilizzato nella modifica di proteine e peptidi, poiché può reagire selettivamente con gruppi tiolici, facilitando lo studio della struttura e della funzione delle proteine. Inoltre, è utilizzato nella produzione di polimeri e come agente di reticolazione in vari processi chimici. Il composto è solubile in solventi organici come acetone ed etanolo, ma ha una solubilità limitata in acqua. Devono essere adottate precauzioni di sicurezza quando si maneggia N-etilmaleimmide, poiché può essere irritante per la pelle e gli occhi, e sono necessarie condizioni di stoccaggio adeguate per mantenere la sua stabilità.

Formula: C₆H₇NO₂

InChI: InChI=1/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3

InChI key: InChIKey=HDFGOPSGAURCEO-UHFFFAOYSA-N

SMILES: C(C)N1C(=O)C=CC1=O

Sinonimi:

• 1-Ethyl-1H-pyrrole-2,5-dione
• 1-Ethyl-2,5-dihydro-1H-pyrrole-2,5-dione
• Ethylmaleimide
• Maleic acid N-ethylimide
• Maleimide, N-ethyl-
• N-Ethylmaleimid
• N-Ethylmaleimide
• N-etilmaleimida
• NEM
• Nsc 7638
• 1H-Pyrrole-2,5-dione, 1-ethyl-
• N-Ethylmaleimide, (NEM)
• 1-Ethyl-1H-pyrrole-2,5-dione~NEM
• ethvlmaleimide
• 1-ethyl-1h-pyrrole-5-dione
• USAF B-121
• maleicacidn-ethylimide
• N-ETHYLMALEIMIDE SIGMAULTRA
• N-ETHYLMALEIMIDE 99+%
• n-ethvlmaleimide
• n-ethyl-maleimid
• 5-dione,1-ethyl-1H-Pyrrole-2
• N-Ethylmaleimide-D5
• usafb-121

N-Ethylmaleimide

CAS: 128-53-0

Formula: C₆H₇NO₂

Purezza: >98.0%(HPLC)(N)

Colore e forma: White powder to crystal

Peso molecolare: 125.13

Ref: 3B-E0136

N-Ethylmaleimide, 99+%

CAS: 128-53-0

N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Micha

Formula: C₆H₇NO₂

Purezza: 99+%

Colore e forma: White to pale cream, Crystals or powder or crystalline powder and/or chunks

Peso molecolare: 125.13

Ref: 02-040526

N-Ethylmaleimide, 98+%

CAS: 128-53-0

Cysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and pe

Formula: C₆H₇NO₂

Purezza: 98+%

Colore e forma: White to cream or pale yellow, Crystals or powder or crystalline powder and/or lumps/chunks or fused solid

Peso molecolare: 125.13

Ref: 02-L00355

1H-Pyrrole-2,5-dione, 1-ethyl-

CAS: 128-53-0

Formula: C₆H₇NO₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 125.1253

Ref: IN-DA000XNW

N-Ethylmaleimide

CAS: 128-53-0

N-Ethylmaleimide

Purezza: 98%

Peso molecolare: 125.13g/mol

Ref: 54-OR1014360

N-Ethylmaleimide

CAS: 128-53-0

N-Ethylmaleimide

Purezza: ≥98%

Peso molecolare: 125.13g/mol

Ref: 54-BUP17154

N-Ethylmaleimide

CAS: 128-53-0

Formula: C₆H₇NO₂

Purezza: (GC) ≥ 98.0%

Colore e forma: White to light-yellow crystalline powder

Peso molecolare: 125.13

Ref: 7W-GK7362

N-Ethylmaleimide

CAS: 128-53-0

N-Ethylmaleimide (NEM) is a reagent for alkylation of free sulfhydryl groups, a cysteine protease inhibitor. Cost-effective and quality-assured.

Formula: C₆H₇NO₂

Purezza: 99.50%

Colore e forma: White Solid

Peso molecolare: 125.13

Ref: TM-T3088

N-Ethyl Maleimide (1M Solution in Acetonitrile)

Prodotto controllato

CAS: 128-53-0

Formula: C₆H₇NO₂

Colore e forma: Single Solution

Peso molecolare: 125.13

Ref: TR-KIT4159

N-Ethyl Maleimide

Prodotto controllato

CAS: 128-53-0

Applications Reagent for the covalent modification of cysteine residues in proteins.NEM gives a clear solution in ethanol at 50 mg/ml. NEM dissolves in water (>50 mg in 4 ml); however, aqueous solutions are unstable. The rate of hydrolysis is pseudo-first order and significantly dependent on pH.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sheehan, M., et al.: J. Cell Biol., 106, 1 (1988), Vogel, K., et al.: J. Biol. Chem., 275, 2959 (2000), Ramos, C., et al.: Biochem. J., 400, 393 (2006),

Formula: C₆H₇NO₂

Colore e forma: Neat

Peso molecolare: 125.13

Ref: TR-E817900

N-Ethyl maleimide

CAS: 128-53-0

N-Ethyl maleimide is a cytosolic calcium chelator that binds to the calcium ions in the cells. It has been shown to inhibit the enzymes of fatty acid synthesis and phospholipase A2, which are involved in lipid metabolism. N-Ethyl maleimide is an irreversible enzyme inhibitor and can be used as a chemical tool for cell sample preparation. The reaction with N-ethyl maleimide leads to a decrease in water permeability of the cell membrane. This chemical also has a high affinity for sulfhydryl groups and can therefore be used as an anti-oxidant or free radical scavenger.

Formula: C₆H₇NO₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 125.13 g/mol

Ref: 3D-FE05855

N-Ethylmaleimide

CAS: 128-53-0

Formula: C₆H₇NO₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 125.127

Ref: 10-F047870

N-Ethylmaleimide ExiPlus, Multi-Compendial, 99%

CAS: 128-53-0

Formula: C₆H₇NO₂

Purezza: min. 99%

Colore e forma: White, Crystalline powder, Clear, Colourless

Peso molecolare: 125.13

Ref: SR-81176

N-Ethylmaleimide extrapure, 99%

CAS: 128-53-0

Formula: C₆H₇NO₂

Purezza: min. 99%

Colore e forma: White to off-white to pale yellow, Crystalline powder / Crystals

Peso molecolare: 125.13

Ref: SR-78503