CAS 128-62-1

1(3H)-Isobenzofuranone, 6,7-dimetossi-3-[(5R)-5,6,7,8-tetraidro-4-metossi-6-metil-1,3-diossolo[4,5-g]isochinolin-5-il]-, (3S)-

Descrizione:

1(3H)-Isobenzofuranone, 6,7-dimetossi-3-[(5R)-5,6,7,8-tetraidro-4-metossi-6-metil-1,3-diossolo[4,5-g]isochinolin-5-il]-, (3S)-, noto con il suo numero CAS 128-62-1, è un composto organico complesso caratterizzato dalle sue uniche caratteristiche strutturali, inclusi un nucleo di isobenzofuranone fuso e un moiety di dioxoloisoquinolina. Questo composto presenta una gamma di gruppi funzionali, inclusi gruppi metossi e dioxole, che contribuiscono alla sua reattività chimica e potenziale attività biologica. È tipicamente un solido a temperatura ambiente e può mostrare una solubilità moderata in solventi organici. La stereochimica indicata dalle designazioni (5R) e (3S) suggerisce specifici arrangiamenti spaziali di atomi, che possono influenzare le interazioni del composto nei sistemi biologici. Tali composti sono spesso di interesse nella chimica medicinale a causa delle loro potenziali proprietà farmacologiche, incluse attività anti-infiammatorie o antitumorali. Tuttavia, sono necessari studi dettagliati per chiarire completamente le sue proprietà e applicazioni in vari campi, inclusi farmaceutici e sintesi organica.

Formula: C₂₂H₂₃NO₇

InChI: InChI=1/C22H23NO7.ClH/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18;/h5-6,9,17-18H,7-8,10H2,1-4H3;1H/t17-,18-;/m1./s1

InChI key: InChIKey=AKNNEGZIBPJZJG-MSOLQXFVSA-N

SMILES: O(C)C=1C=2[C@@](N(C)CCC2C=C3C1OCO3)([C@@]4(C=5C(C(=O)O4)=C(OC)C(OC)=CC5)[H])[H]

Sinonimi:

• (-)-Narcotine
• (-)-α-Narcotine
• (3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone
• 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[ 4,5-g]isoquinolin-5-yl)-, [S-(R*,S*)]-
• 1,3-Dioxolo[4,5-g]isoquinoline, 1(3H)-isobenzofuranone deriv.
• 1-α-Narcotine
• <span class="text-smallcaps">L</span>-α-Noscapine
• Capval
• Coscopin
• Coscotabs
• L-α-Noscapine
• Longactin
• Longatin
• Lyobex
• Methoxyhydrastine
• Narcompren
• Narcosine
• Narcotin
• Narcotussin
• Narkotin
• Nectadon
• Nicolane
• Nipaxon
• Noscapalin
• Noscapin
• Noscapina
• Noscapine
• Nsc 5366
• O-Methylarcotoline
• O-Methylnarcotoline
• Opian
• Opianin
• Opianine
• Terbenol
• Tusscapine
• Vadebex
• l-α-Narcotine
• 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (3S)-
• (3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-2-benzofuran-1(3H)-one
• (3R)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-2-benzofuran-1(3H)-one
• 6,7-dimethoxy-3-(4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-2-benzofuran-1(3H)-one
• (3R)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-2-benzofuran-1(3H)-one hydrochloride
• 6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-isobenzofuran-1-one
• tusseapine
• L-α-Narcotin
• l-alpha-2-methyl-8-methoxy-6,7-methylenedioxy-1-(6,7-dimethoxy-3-phthalidyl)-1
• Hederix (free base)
• Vadebe
• Key-Tusscapine
• Narcotine (7CI, 8CI)
• 5-g]isoquinolin-5-yl)-,[s-(theta,s)]-3-dioxolo[4
• Phthalide, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-
• (S)-6,7-DIMETHOXY-3-((R)-4-METHOXY-6-METHYL-5,6,7,8-TETRAHYDRO-[1,3]DIOXOLO[4,5-G]ISOQUINOLIN-5-YL)-3H-ISOBENZOFURAN-1-ONE
• NOSCAPINE (NARCOTINE) NATURALLY OCCURRIN G O
• 1-alpha-Narcotine
• Detusso
• Noscapine (100 mg)
• Noscapine (Narcotine) base
• Noscapine (base and/or unspecified salts)
• Ecasil
• S(R*,S*)-6,7-DIMETHOXY-3-(5,6,7,8-TETRAHYDRO-4-METHOXY-6-METHYL-1,3-DIOXOLO[4,5-G]-ISOQUINOLIN-5-YL)-1(3H)-ISOBENZOFURANONE
• (S,R)-NOSCAPINE
• [S-(R*,S*)]-6,7-Dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-1(3H)-Isobenzofuranone
• ,2,3,4-tetrahydroisoquinaline
• Gnoscopine [dl-form]
• Terial
• 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1(3h)-isobenzofuranon
• dl-Narcotine [dl-form]
• 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (3S)- (9CI)
• alpha-Narcotine
• nsc5366
• 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-1(3H)-isobenzofuranone, [S-(R*,S*)]
• Noscapine (500 mg)
• 5-g)isoquinolin-5-yl)-,(s-(r*,s*))-3-dioxolo(4
• Noscapal
• L-ALPHA-NARCOTINE

Noscapine Hydrochloride

CAS: 128-62-1, 219533-73-0, 912-60-7

Formula: C₂₂H₂₃NO₇·HCl

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 449.88

Ref: 3B-N0963

Noscapine

CAS: 128-62-1

Colore e forma: Neat

Ref: 61-FOR1232.00

Noscapine 1.0 mg/ml in Acetonitrile

CAS: 128-62-1

Colore e forma: Single Solution

Ref: 61-AMP1232.00-11

NOSCAPINE CRS

CAS: 128-62-1

NOSCAPINE CRS

Formula: C₂₂H₂₃NO₇

Colore e forma: Added Modified

Peso molecolare: 413.4205

Ref: 41-N1300000

Noscapine

CAS: 128-62-1

Alkaloids of opium and their derivatives, salts thereof, not elsewhere specified or included

Formula: C₂₂H₂₃NO₇

Colore e forma: White Powder

Peso molecolare: 413.14745

Ref: 45-1474504

Noscapine

CAS: 128-62-1

Formula: C₂₂H₂₃NO₇

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 413.4205

Ref: IN-DA007O3K

Noscapine

CAS: 128-62-1

Formula: C₂₂H₂₃NO₇

Colore e forma: White To Off-White Solid

Peso molecolare: 413.43

Ref: 4Z-N-061012

Noscapine-13C-d3

CAS: 128-62-1

Formula: CC₂₁H₂₀D₃NO₇

Colore e forma: White To Off-White Solid

Peso molecolare: 417.44

Ref: 4Z-N-061001

Noscapine

CAS: 128-62-1

Colore e forma: Neat

Ref: 86-MM1232.00

Noscapine

Prodotto controllato

CAS: 128-62-1

Formula: C₂₂H₂₃NO₇

Colore e forma: Neat

Peso molecolare: 413.42

Ref: 04-C15652400

Noscapine

CAS: 128-62-1

Applications Antitussive.
References Tsunoda, N., et al.: Xenobiotica, 9, 181 (1979), Dhalstroem, B., et al.: Eur. J. Clin. Pharmacol., 22, 535 (1982), Al-Yahya, M.A., et al.: Anal. Profiles Drug Subs., 11, 407 (1982),

Formula: C₂₂H₂₃NO₇

Colore e forma: White

Peso molecolare: 413.42

Ref: TR-N882000

Noscapine base

CAS: 128-62-1

Noscapine base is a natural alkaloid compound, which is derived from the opium poppy, Papaver somniferum. This bioactive compound modulates the microtubule assembly in cells, impacting the dynamic instability of microtubules, which is crucial in mitosis and cell division. The resultant modulation disrupts microtubule function, thereby exerting a cytostatic effect that hampers the proliferation of malignant cells.

Formula: C₂₂H₂₃NO₇

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 413.43 g/mol

Ref: 3D-FN09246