CAS 128517-07-7

(1S,4Z,7S,10S,11E,20R)-4-etilidene-7,20-dipropan-2-il-9-ossa-15,16-ditia-3,6,18,21-tetrazabiciclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone

Descrizione:

La sostanza chimica con il nome "(1S,4Z,7S,10S,11E,20R)-4-etilidene-7,20-dipropan-2-il-9-oxa-15,16-ditia-3,6,18,21-tetrazabiciclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone" e numero CAS "128517-07-7" è un composto organico complesso caratterizzato dalla sua unica struttura biciclica, che incorpora più gruppi funzionali, inclusi i moieties oxo e thia. La stereochimica indicata dalle designazioni (S) e (Z) suggerisce specifici arrangiamenti spaziali degli atomi, che possono influenzare significativamente la reattività e le interazioni del composto. La presenza di più gruppi alchilici, come etilidene e dipropan-2-il, contribuisce alle sue caratteristiche idrofobiche, mentre il telaio biciclico può conferire rigidità alla molecola. Questo composto probabilmente mostrerà interessanti proprietà chimiche, inclusa una potenziale attività biologica, a causa della sua struttura intricata. Le sue applicazioni potrebbero spaziare in vari campi, inclusi farmaceutici e scienza dei materiali, sebbene gli usi specifici dipenderebbero da ulteriori ricerche sulle sue proprietà e sul comportamento in diversi ambienti.

Formula: C₂₄H₃₆N₄O₆S₂

InChI: InChI=1/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/b9-7+,16-6-/t15-,17+,19+,20-/m0/s1

Sinonimi:

• Fr 901228
• Romidepsin
• (1R,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(1-methylethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone

Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl], cyclic (3→5)-disulfide

CAS: 128517-07-7

Formula: C₂₄H₃₆N₄O₆S₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 540.6958

Ref: IN-DA000Y5C

Romidepsin

CAS: 128517-07-7

Romidepsin

Purezza: ≥98%

Peso molecolare: 540.7g/mol

Ref: 54-BUP04661

Romidepsin

CAS: 128517-07-7

Formula: C₂₄H₃₆N₄O₆S₂

Peso molecolare: 540.69

Ref: 4Z-R-160001

Romidepsin

CAS: 128517-07-7

Romidepsin (NSC-630176), an IV histone deacetylase inhibitor, treats refractory cutaneous/peripheral T-cell lymphomas.

Formula: C₂₄H₃₆N₄O₆S₂

Purezza: 99.4% - 99.94%

Colore e forma: Solid

Peso molecolare: 540.7

Ref: TM-T6006

Romidepsin

Prodotto controllato

CAS: 128517-07-7

Applications Romidepsin is a histone deacetylase inhibitor that can alter chromatin structure and gene transcription leading to multiple changes in cellular protein production. This may result in cell cycle arrest and tumor growth inhibition. Romidepsin has shown anti-proliferative activity in vitro against multiple mouse and human tumor cell lines and in vivo in human tumor xenograft models. Romidepsin can be administered with a second agent, such as a cytotoxic agent, a steroidal agent, a proteasome inhibitor, or a kinase inhibitor.
References Ueda, H., et al.: J. Antibiot., 47, 301 (1994), Weidle, U., et al.: Anticancer Res., 20, 1471 (2000), Kitazono, M., et al.: Cancer Res., 61, 6328 (2001), Sandor, V., et al.: Clin. Cancer Res., 8, 718 (2002),

Formula: C₂₄H₃₆N₄O₆S₂

Colore e forma: White To Off-White

Peso molecolare: 540.70

Ref: TR-R425060

Romidepsin

CAS: 128517-07-7

Natural anti-cancer agent; inhibitor of histone deacetylases

Formula: C₂₄H₃₆N₄O₆S₂

Purezza: Min. 95 Area-%

Colore e forma: White Powder

Peso molecolare: 540.7 g/mol

Ref: 3D-FR10656

Romidepsin - Bio-X ™

CAS: 128517-07-7

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₂₄H₃₆N₄O₆S₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 540.7 g/mol

Ref: 3D-BR300116

Romidepsin

CAS: 128517-07-7

Purezza: 98%

Peso molecolare: 540.69

Ref: 10-F979349

Romidepsin-d8

Prodotto controllato

CAS: 128517-07-7

Applications Labelled Romidepsin (R425060). Romidepsin is a histone deacetylase inhibitor that can alter chromatin structure and gene transcription leading to multiple changes in cellular protein production. This may result in cell cycle arrest and tumor growth inhibition. Romidepsin has shown anti-proliferative activity in vitro against multiple mouse and human tumor cell lines and in vivo in human tumor xenograft models. Romidepsin can be administered with a second agent, such as a cytotoxic agent, a steroidal agent, a proteasome inhibitor, or a kinase inhibitor.
References Ueda, H., et al.: J. Antibiot., 47, 301 (1994), Weidle, U., et al.: Anticancer Res., 20, 1471 (2000), Kitazono, M., et al.: Cancer Res., 61, 6328 (2001), Sandor, V., et al.: Clin. Cancer Res., 8, 718 (2002),

Formula: C₂₄D₈H₂₈N₄O₆S₂

Colore e forma: Neat

Peso molecolare: 548.745

Ref: TR-R425062