CAS 129-74-8

Cloridrato di buclizina

Descrizione:

Cloridrato di buclizina è un antistaminico utilizzato principalmente per alleviare i sintomi del mal d'auto e per trattare le allergie. Appartiene alla classe dei composti della piperazina ed esplica proprietà sedative, rendendolo efficace nella riduzione della nausea e del vomito associati ai viaggi. La sostanza è caratterizzata dalla sua capacità di bloccare i recettori dell'istamina H1, il che aiuta a mitigare le reazioni allergiche. Cloridrato di buclizina è tipicamente somministrato per via orale ed è noto per la sua durata d'azione relativamente lunga. In termini di proprietà fisiche, è una polvere cristallina bianca o bianco sporco solubile in acqua e alcol. Il composto ha una formula molecolare che riflette la sua struttura complessa, contribuendo ai suoi effetti farmacologici. Sebbene generalmente ben tollerato, può causare effetti collaterali come sonnolenza, secchezza delle fauci e vertigini. Come con qualsiasi medicinale, è importante utilizzare Cloridrato di buclizina sotto supervisione medica per garantire sicurezza ed efficacia, in particolare in individui con condizioni di salute preesistenti o che assumono altri farmaci.

Formula: C₂₈H₃₃ClN₂·2ClH

InChI: InChI=1S/C28H33ClN2.2ClH/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24;;/h4-16,27H,17-21H2,1-3H3;2*1H

InChI key: InChIKey=SDBHDSZKNVDKNU-UHFFFAOYSA-N

SMILES: C(N1CCN(CC2=CC=C(C(C)(C)C)C=C2)CC1)(C3=CC=C(Cl)C=C3)C4=CC=CC=C4.Cl

Sinonimi:

• 1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride
• 1-(4-Tert-Butylbenzyl)-4-[(4-Chlorophenyl)(Phenyl)Methyl]Piperazine Dihydrochloride
• 1-(p-Chlorobenzhydryl)-4-(p-tert-butylbenzyl)diethylenediamine hydrochloride
• 1-(p-tert-Butylbenzyl)-4-(p-chlorodiphenylmethyl)piperazine dihydrochloride
• 1-p-Chlorobenzhydryl-4-p-(t)-butylbenzylpiperazine dihydrochloride
• Aphilan R
• Bucladin S
• Buclina
• Buclizine HCl
• Buclizine Hydrochloride
• Buclodin
• Histabutyzine hydrochloride
• Longifene
• NSC 25141
• Piperazine, 1-(p-tert-butylbenzyl)-4-(p-chloro-α-phenylbenzyl)-, dihydrochloride
• Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-, dihydrochloride
• Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-, hydrochloride (1:2)
• Softran
• Ucb 4445
• Vibazine

Buclizine Hydrochloride

CAS: 129-74-8

Colore e forma: Neat

Ref: 61-FOR0475.00

Buclizine hydrochloride impurity standard

CAS: 129-74-8

Buclizine hydrochloride impurity standard

Colore e forma: White

Ref: 47-440

Buclizine dihydrochloride

CAS: 129-74-8

Formula: C₂₈H₃₅Cl₃N₂

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 505.9499

Ref: IN-DA007NAA

Buclizine dihydrochloride

CAS: 129-74-8

Buclizine dihydrochloride

Purezza: ≥98%

Peso molecolare: 505.95g/mol

Ref: 54-BUP14697

Buclizine DiHCl

CAS: 129-74-8

Formula: C₂₈H₃₃ClN₂·2HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 433.04 2*36.46

Ref: 4Z-B-211

Buclizine Dihydrochloride

CAS: 129-74-8

Buclizine Dihydrochloride

Purezza: 99%

Peso molecolare: 505.95g/mol

Ref: 54-OR1028300

Buclizine Hydrochloride

Prodotto controllato

CAS: 129-74-8

Formula: C₂₈H₃₃ClN₂ClH

Colore e forma: Neat

Peso molecolare: 505.95

Ref: 86-MM0475.00

Buclizine dihydrochloride

CAS: 129-74-8

Buclizine dihydrochloride (Buclina) is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and

Formula: C₂₈H₃₃ClN₂·2HCl

Purezza: 98.05%

Colore e forma: Off-White Powder

Peso molecolare: 505.95

Ref: TM-T6426

Buclizine-d8 DiHCl

CAS: 129-74-8

Formula: C₂₈H₂₅D₈ClN₂·2HCl

Peso molecolare: 441.14 2 36.46

Ref: 4Z-B-212

Buclizine, Dihydrochloride

Prodotto controllato

CAS: 129-74-8

Applications Used as an antiemetic.
References Jorgensen, P.B., et al.: Curr. Ther. Res., 16, 1276 (1974), Adam, E.I.: J. Int. Med. Res., 15, 71 (1987)

Formula: C₂₈H₃₃ClN₂·2ClH

Colore e forma: White

Peso molecolare: 505.95

Ref: TR-B689450

Buclizine Dihydrochloride

CAS: 129-74-8

Formula: C₂₈H₃₃ClN₂(HCl)

Peso molecolare: 433.0 : 2(36.5)

Ref: ST-EA-CP-B30003

Buclizine dihydrochloride

CAS: 129-74-8

Buclizine is a tricyclic antidepressant that inhibits the activity of dopamine receptors. It can be used to treat nausea and vomiting, which are symptoms of many chronic diseases, including cancer. Buclizine also has anti-infectious effects and can inhibit the growth of bacteria by preventing their ability to synthesize DNA. This drug is used as an antimicrobial agent for the treatment of infectious diseases such as syphilis and leprosy. The hypoglycemic effect of buclizine may be due to its ability to inhibit insulin release or to decrease the production of glucose by liver cells.

Formula: C₂₈H₃₅Cl₃N₂

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 505.95 g/mol

Ref: 3D-FB146989

Buclizine (piperazine-d8) Dihydrochloride

Prodotto controllato

CAS: 129-74-8

Applications Buclizine (piperazine-d8) Dihydrochloride used as an antiemetic. It is the labelled version of B689450.
References Jorgensen, P.B., et al.: Curr. Ther. Res., 16, 1276 (1974); Adam, E.I.: J. Int. Med. Res., 15, 71 (1987)

Formula: C₂₈H₂₇D₈Cl₃N₂

Colore e forma: Neat

Peso molecolare: 441.077

Ref: TR-B689452