CAS 130-26-7
:Cliochinolo
Descrizione:
Cliochinolo, con il numero CAS 130-26-7, è un composto organico che appartiene alla classe dei derivati della chinolina. È principalmente riconosciuto per il suo utilizzo come agente antimicrobico ed è stato impiegato nel trattamento di varie infezioni gastrointestinali. Cliochinolo presenta un aspetto cristallino giallo ed è solubile in solventi organici, come etanolo e cloroformio, ma ha una solubilità limitata in acqua. Il composto possiede proprietà antibatteriche e antifungine, rendendolo efficace contro una gamma di patogeni. Tuttavia, il suo utilizzo è stato associato a una potenziale neurotossicità, portando a restrizioni nelle sue applicazioni cliniche. Cliochinolo agisce chelando ioni metallici, il che può interrompere il metabolismo microbico. La sua struttura chimica include un anello di chinolina e un gruppo idrossile, contribuendo alla sua attività biologica. A causa della sua importanza storica e delle controversie riguardanti la sua sicurezza, Cliochinolo rimane oggetto di ricerca, in particolare nel contesto delle malattie neurodegenerative e dei suoi potenziali ruoli terapeutici.
Formula:C9H5ClINO
InChI:InChI=1/C10H6ClIO/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,13H
InChI key:InChIKey=QCDFBFJGMNKBDO-UHFFFAOYSA-N
SMILES:OC=1C2=C(C(Cl)=CC1I)C=CC=N2
Sinonimi:- 5-Chloro-7-iodo-8-hydroxyquinoline
- 5-Chloro-7-iodo-8-oxyquinoline
- 5-Chloro-7-iodo-8-quinolinol
- 5-Chloro-7-iodoquinolin-8-ol
- 7-Iodo-5-chloro-8-hydroxyquinoline
- 7-Iodo-5-chloroxine
- 8-Hydroxy-7-iodo-5-chloroquinoline
- 8-Quinolinol, 5-chloro-7-iodo-
- Alchloquin
- Amebil
- Amoenol
- Bactol
- Barquinol
- Budoform
- Chinoform
- Chloroiodoquin
- Chloroiodoquine
- Chlorojodochin
- Cifoform
- Clioquinol
- Cliquinol
- Cort-Quin
- Dioquinol
- Dizenterol
- Eczecidin
- Emaform
- Entero-Vioform
- Enteroquinol
- Enteroseptol
- Enterozol
- Entrokin
- Hi-Eneterol
- Hi-Enterol
- Iodenterol
- Iodochlorhydroxyquin
- Iodochlorhydroxyquinol
- Iodochlorohydroxyquin
- Iodochlorohydroxyquinoline
- Iodochloroquine
- Iodochloroxine
- Iodochloroxyquinoline
- Iodoenterol
- Iodoxyquinoline
- Lekosept
- NSC 3531
- NSC 74938
- Nioform
- Quin-O-Creme
- Quinambicide
- Quinidochlor
- Quiniodochlor
- Quinoform
- Quinoform (antiseptic)
- Rheaform
- Rheaform Boluses
- Rometin
- Vioform
- Vioformio
- 5-Chlor-7-jod-8-hydroxy-chinolin
- AKOS B020410
- ala-quin
- 5-chloro-7-iodo-8-quinolino
- alchoquin
- chloroiodeoquim
- N-IODO-5-CHLORO-8-HYDROXYQUINOLINE
- Vedi altri sinonimi
Ordinare per
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17 prodotti.
5-Chloro-8-hydroxy-7-iodoquinoline
CAS:Formula:C9H5ClINOPurezza:>97.0%(T)Colore e forma:Light yellow to Brown to Dark green powder to crystalPeso molecolare:305.50CLIOQUINOL CRS
CAS:CLIOQUINOL CRSFormula:C9H5ClINOColore e forma:White. Whitish. Yellow. Dark. Powder.Peso molecolare:305.4996Clioquinol
CAS:ClioquinolFormula:C9H5ClINOPurezza:99.9%Colore e forma:Off-WhitePeso molecolare:304.91044Clioquinol
CAS:Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fusedFormula:C9H5ClINOColore e forma:PowderPeso molecolare:304.910445-Chloro-7-Iodoquinolin-8-ol
CAS:Formula:C9H5ClINOPurezza:97%Colore e forma:SolidPeso molecolare:305.4996Clioquinol
CAS:Clioquinol: oral, lipophilic copper-binder; halogenated quinoline with antifungal, antiparasitic, and possible antitumor uses.Formula:C9H5ClINOPurezza:97.02%Colore e forma:Brownish-Yellow Bulky Powder Decomposes At 178-179°C Used As A Topical Anti-InfectivePeso molecolare:305.5Clioquinol
CAS:Formula:C9H5ClINOPurezza:≥ 95.0%Colore e forma:White to light-yellow, yellow or brown powder or crystalsPeso molecolare:305.495-Chloro-8-hydroxy-7-iodoquinoline
CAS:5-Chloro-8-hydroxy-7-iodoquinolineFormula:C9H5ClINOPurezza:≥95%Colore e forma: cream powderPeso molecolare:305.50g/molRef: 4Z-C-805
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaClioquinol
CAS:Prodotto controllatoApplications Clioquinol is used as an antiparasitic compound, known to induce apoptosis in leukemia and myeloma cells.
References Cao, B. et al.: J. Biol. Chem., 288, 34181 (2013); Chen, Z. et al.: Eur J. Med. Chem., 68, 454 (2013);Formula:C9H5ClINOColore e forma:NeatPeso molecolare:305.55-Chloro-7-iodo-8-hydroxyquinoline
CAS:5-Chloro-7-iodo-8-hydroxyquinoline is a metal chelate that has been shown to have pharmacological effects in experimental animals. It has antioxidative properties and can protect against oxidative injury. 5-Chloro-7-iodo-8-hydroxyquinoline was found to be toxic in various animal models, including the neuronal death and mitochondrial membrane potential. This toxicity may be due to its ability to inhibit the activity of DNA polymerase and protein synthesis. The compound also showed significant cytotoxicity at low concentrations, but had no significant cytotoxicity at higher concentrations. 5-Chloro-7-iodo-8-hydroxyquinoline is similar in structure to clioquinol, which has been shown to have neurotoxic effects in humans.Formula:C9H5ClINOPurezza:Min. 95 Area-%Colore e forma:PowderPeso molecolare:305.5 g/molClioquinol - Bio-X ™
CAS:Clioquinol is an antifungal drug and antiprotozoal drug that has been shown to inhibit the activity of protein kinase-3 and to promote apoptosis. This compound has also been found to improve iron homeostasis, which may be due to its ability to counteract the effects of oxidative stress on the mitochondria. Additionally, it has been shown to have anti-fungal properties against opportunistic fungal pathogens such as Candida albicans. Clioquinol is extracted from a plant called "Clioquinia rosea" and is produced by a chemical reaction with 2-chloroethanol.
Formula:C9H5ClINOPurezza:Min. 95%Colore e forma:PowderPeso molecolare:305.5 g/mol5-Chloro-7-Iodo-8-Quinolinol (Clioquinol, Iodochlorohydroxyquinoline) ExiPlus, Multi-Compendial, 97-103%
CAS:Formula:C9H5ClINOPurezza:97.0-103.0%Colore e forma:White to Light Yellow to Light Beige, Powder or Crystals, ClearPeso molecolare:305.5
