CAS 130-61-0

Cloridrato di tioridazina

Descrizione:

Cloridrato di tioridazina è un farmaco antipsicotico utilizzato principalmente per trattare la schizofrenia e altri disturbi psicotici. Appartiene alla classe dei composti fenotiazici, caratterizzati da una struttura a tre anelli che include un atomo di zolfo. La tioridazina agisce principalmente come antagonista della dopamina, bloccando i recettori della dopamina nel cervello, il che aiuta ad alleviare i sintomi della psicosi. La forma di sale cloridrato ne migliora la solubilità e la stabilità. In termini di caratteristiche fisiche, Cloridrato di tioridazina è tipicamente una polvere cristallina bianca o bianco sporco. È solubile in acqua e alcol, con un punto di fusione relativamente basso. Il composto può presentare effetti collaterali, tra cui sedazione, effetti anticolinergici e potenziali problemi cardiovascolari, richiedendo un attento monitoraggio durante il trattamento. Inoltre, la tioridazina è stata associata a un rischio di prolungamento del QT, che può portare a gravi disturbi del ritmo cardiaco. Come per qualsiasi farmaco, è essenziale utilizzare Cloridrato di tioridazina sotto la guida di un professionista sanitario, considerando i suoi benefici terapeutici e i potenziali rischi.

Formula: C₂₁H₂₆N₂S₂·ClH

InChI: InChI=1S/C21H26N2S2.ClH/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23;/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;1H

InChI key: InChIKey=NZFNXWQNBYZDAQ-UHFFFAOYSA-N

SMILES: C(CC1N(C)CCCC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(SC)C3.Cl

Sinonimi:

• 10-(2-(1-Methyl-2-Piperidinyl)Ethyl)-2-(Methylthio)-10H-Phenothiazinmono
• 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazinmonohydrochl
• 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylthiophenothiazinehydrochloride
• 10-[2-(1-Methyl-2-Piperidyl)-Ethyl]-2-[Methylthiol]-Phenothiazine Hydrochloride
• 10-[2-(1-Methyl-2-Piperidyl)Ethyl]-2-(Methylthio)-10H-Phenothiazine Hydrochloride
• 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride
• 10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride
• 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride (1:1)
• 10-[3-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine hydrochloride
• 10H-Phenothiazine, 10-2-(1-methyl-2-piperidinyl)ethyl-2-(methylthio)-, monohydrochloride
• 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, hydrochloride (1:1)
• 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, monohydrochloride (9CI)
• 2-Methylmercapto-10-[2-(N-methyl-2-piperidyl)ethyl]phenothiazine Hydrochloride
• 2-methylmercapto-10-(2-(n-methyl-2-piperidyl)ethyl)phenothiazinehydrochlorid
• Aldazine
• Labotest-Bb Lt00451961
• Mallorol
• Mellaril
• Mellaril hydrochloride
• Melleretten
• Melleril
• NSC 186060
• Novoridazine
• Orsanil
• Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)-, hydrochloride
• Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)-, monohydrochloride
• Ridazin
• Stalleril
• THIORIDAZINEHYDROCHLORIDE,USP
• ThioridazinHCl
• Thioridazine Hcl
• Thioridazinhydrochlorid
• Thioril
• Thiozine
• mellarilhydrochloride
• melleril(tablet)
• usafsz-3
• 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazinmonohydrochl
• 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylthiophenothiazinehydrochloride
• 2-methylmercapto-10-(2-(n-methyl-2-piperidyl)ethyl)phenothiazinehydrochlorid
• mellarilhydrochloride
• melleril(tablet)
• usafsz-3
• ThioridazinHCl
• Thioridazinhydrochlorid
• 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride
• 2-Methylmercapto-10-[2-(N-methyl-2-piperidyl)ethyl]phenothiazine Hydrochloride
• Orsanil
• Ridazin
• Stalleril
• 10H-Phenothiazine, 10-2-(1-methyl-2-piperidinyl)ethyl-2-(methylthio)-, monohydrochloride
• THIORIDAZINEHYDROCHLORIDE,USP

Thioridazine Hydrochloride

CAS: 130-61-0, 50-52-2

Formula: C₂₁H₂₆N₂S₂·HCl

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 407.03

Ref: 3B-T3102

Thioridazine Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 130-61-0

Colore e forma: Single Solution

Ref: 61-AMP0116.00-01

Thioridazine Hydrochloride

CAS: 130-61-0

Colore e forma: Neat

Ref: 61-FOR0116.00

THIORIDAZINE HYDROCHLORIDE CRS

CAS: 130-61-0

THIORIDAZINE HYDROCHLORIDE CRS

Formula: C₂₁H₂₇ClN₂S₂

Colore e forma: Powder

Peso molecolare: 407.0355

Ref: 41-T1300000

Thioridazine Hydrochloride

CAS: 130-61-0

Antidepressants, tranquilizers and other pschotherapeutic agents

Formula: C₂₁H₂₆N₂S₂·ClH

Colore e forma: Powder

Peso molecolare: 406.13042

Ref: 45-1663008

Thioridazine hydrochloride

CAS: 130-61-0

Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4

Formula: C₂₁H₂₇ClN₂S₂

Purezza: 99.55% - 99.957%

Colore e forma: White To Off-White Solid

Peso molecolare: 407.04

Ref: TM-T0365

Thioridazine HCl

CAS: 130-61-0

Formula: C₂₁H₂₆N₂S₂·HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 370.58 36.46

Ref: 4Z-T-481

Thioridazine hydrochloride

CAS: 130-61-0

Thioridazine hydrochloride

Purezza: ≥98%

Peso molecolare: 407.04g/mol

Ref: 54-BUP14979

Thioridazine hydrochloride

CAS: 130-61-0

Formula: C₂₁H₂₆N₂S₂·HCl

Purezza: ≥ 98.0%

Colore e forma: White to off-white powder or crystals

Peso molecolare: 407.03

Ref: 7W-GP3742

Thioridazine Hydrochloride

Prodotto controllato

CAS: 130-61-0

Formula: C₂₁H₂₆N₂S₂·ClH

Colore e forma: Neat

Peso molecolare: 407.04

Ref: 86-MM0116.00

Thioridazine.HCl

CAS: 130-61-0

Colore e forma: Neat

Ref: LP-TRD-1839-HC-10

Thioridazine hydrochloride

Prodotto controllato

CAS: 130-61-0

Formula: C₂₁H₂₆N₂S₂·ClH

Colore e forma: Neat

Peso molecolare: 407.04

Ref: 04-C17560200

10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride

CAS: 130-61-0

10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride

Formula: C₂₁H₂₆N₂S₂·ClH

Purezza: 98%

Colore e forma: white solid

Peso molecolare: 407.04g/mol

Ref: 54-OR20007

Thioridazine Hydrochloride

Prodotto controllato

CAS: 130-61-0

Applications Thioridazine HCl is a dopamine receptor blocker and antipsychotic. It is the parent compound of sulforidazine and mesoridazine. This compound has been reported to bind strongly to dopamine receptors on cancer stem cells and cause differentiation leaving normal cells alone (see Can. Chem. News 12 July/August 2012).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Goldenthal, E.I., Toxicol. Appl. Pharmacol., 18, 185 (1971), Abdel-Moety, E.M., et al.: Anal. Profile Drug Subs., 18, 459 (1989),

Formula: C₂₁H₂₆N₂S₂·ClH

Colore e forma: Light Yellow

Peso molecolare: 407.04

Ref: TR-T368800

10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride

Prodotto controllato

CAS: 130-61-0

The drug, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride (CGP 46660), is a competitive antagonist at the human histamine H3 receptor. It has been shown to bind to the histamine H3 receptor in the range of 0.001 to 1 μM and is selective for this receptor over other receptors. CGP 46660 is an optical sensor that can be used in titration calorimetry experiments to measure changes in heat production when it binds to histamine H3 receptors. The drug also has been shown to inhibit guanine nucleotide-binding protein (G protein) signaling pathways and brain functions such as memory formation, learning, and attention span. These effects were demonstrated in humans by measuring EEG activity. The optimum concentration of CGP 46660 for these effects was found to be between 0.01 and 10 μM.

Formula: C₂₁H₂₇ClN₂S₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 407.04 g/mol

Ref: 3D-FT28238