CAS 130848-06-5

Angelato di decursinolo

Descrizione:

Angelato di decursinolo è un composto chimico classificato come prodotto naturale, specificamente un tipo di derivato della cumarina. È principalmente derivato da piante della famiglia Apiaceae, in particolare dalle radici di Angelica gigas. Questo composto è caratterizzato dalla sua struttura unica, che include un moiety di decursinolo e un gruppo estere di angelato. Angelato di decursinolo mostra varie attività biologiche, comprese proprietà antinfiammatorie, antiossidanti e potenziali proprietà anticancro, rendendolo di interesse nella ricerca farmacologica. La sua solubilità è generalmente moderata nei solventi organici e può avere una solubilità limitata in acqua. La stabilità del composto può essere influenzata da fattori ambientali come luce e temperatura. Come molti prodotti naturali, la sua estrazione e purificazione possono essere complesse, spesso richiedendo metodi specifici per isolarlo da matrici vegetali. In generale, Angelato di decursinolo rappresenta un'area affascinante di studio all'interno della chimica dei prodotti naturali, con potenziali applicazioni in medicina e salute.

Formula: C₁₉H₂₀O₅

InChI: InChI=1S/C19H20O5/c1-5-11(2)18(21)23-16-9-13-8-12-6-7-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/b11-5-/t16-/m0/s1

InChI key: InChIKey=AGABNGOXUSXQDD-XKGFZTIGSA-N

SMILES: CC1(C)OC=2C(C[C@@H]1OC(/C(=C\C)/C)=O)=CC3=C(C2)OC(=O)C=C3

Sinonimi:

• 2-Butenoic acid, 2-methyl-, (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b′]dipyran-7-yl ester, (2Z)-
• 2-Butenoic acid, 2-methyl-, 7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b′]dipyran-7-yl ester, [S-(Z)]-
• 2-Butenoicacid, 2-methyl-, 7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-ylester, [S-(Z)]-
• 2H,6H-Benzo[1,2-b:5,4-b']dipyran, 2-butenoic acid deriv.
• Acutilobin
• Decursinol angelate

Decursinol angelate

CAS: 130848-06-5

Formula: C₁₉H₂₀O₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 328.3591

Ref: IN-DA009B3Z

(S)-8,8-Dimethyl-2-Oxo-7,8-Dihydro-2H,6H-Pyrano[3,2-G]Chromen-7-Yl (Z)-2-Methylbut-2-Enoate

CAS: 130848-06-5

(S)-8,8-Dimethyl-2-Oxo-7,8-Dihydro-2H,6H-Pyrano[3,2-G]Chromen-7-Yl (Z)-2-Methylbut-2-Enoate

Purezza: 98%

Peso molecolare: 328.36g/mol

Ref: 54-OR1023111

Decursinol angelate

CAS: 130848-06-5

Decursinol angelate

Purezza: ≥98%

Peso molecolare: 328.36g/mol

Ref: 54-BUP10926

Decursinol angelate

CAS: 130848-06-5

Formula: C₁₉H₂₀O₅

Peso molecolare: 328.36

Ref: 7W-GY9577

Decursinol angelate

CAS: 130848-06-5

Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion and inflammatory activation of cancer cells through modulation of PI3K/AKT, ERK and NF-kappaB, its anti-inflammatory activity may contribute to its anti-cancer activity.Decursinol angelate has protective effects against amyloid β-protein-induced oxidative stress in the PC12 cell line. It improves wound healing by upregulating the expression of genes encoding extracellular matrix remodeling proteins, inflammatory cytokines, and growth factors. Decursinol angelate has in vitro and in vivo antifungal activity against Magnaporthe oryzae, the causal agent of rice blast.

Formula: C₁₉H₂₀O₅

Purezza: 95%~99%

Peso molecolare: 328.364

Ref: BP-BP1812

Decursinol angelate

CAS: 130848-06-5

Decursinol angelate is anti-tumor, anti-inflammatory, anti-oxidant, hepatoprotective, and inhibits VEGF and cancer cell invasion.

Formula: C₁₉H₂₀O₅

Purezza: 99.93%

Colore e forma: Solid

Peso molecolare: 328.36

Ref: TM-TN1557

Decursinol angelate

CAS: 130848-06-5

Lactone

Formula: C₁₉H₂₀O₅

Purezza: ≥ 90.0 % (HPLC)

Peso molecolare: 328.36

Ref: 5G-84209

Decursinol angelate

CAS: 130848-06-5

Decursinol angelate is a bioactive compound, which is derived from the roots of plants such as Angelica gigas, a species commonly used in traditional Asian medicine. This compound is a coumarin derivative, known for its potential pharmacological properties. Decursinol angelate’s mode of action involves the modulation of inflammatory pathways, particularly through the inhibition of key enzymes and cytokines involved in inflammatory responses, such as COX-2 and TNF-alpha. This modulation leads to a reduction in the synthesis of pro-inflammatory mediators, which can be beneficial in managing inflammation-related conditions.

Formula: C₁₉H₂₀O₅

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 328.36 g/mol

Ref: 3D-FFA84806

Decursinol angelate - Bio-X ™

CAS: 130848-06-5

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₁₉H₂₀O₅

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 328.36 g/mol

Ref: 3D-BD300081