CAS 13345-50-1

PGA2

Descrizione:

PGA2, o Prostaglandina A2, è un composto che si verifica naturalmente e appartiene alla classe delle prostaglandine, che sono composti lipidici derivati dagli acidi grassi. Svolge un ruolo significativo in vari processi fisiologici, tra cui infiammazione, regolazione del flusso sanguigno e modulazione delle risposte immunitarie. PGA2 è caratterizzato dalla sua capacità di interagire con recettori specifici nel corpo, influenzando le attività cellulari e le vie di segnalazione. Tipicamente è un liquido incolore o giallo pallido ed è sensibile alla luce e al calore, il che può influenzare la sua stabilità. Il composto è solubile in solventi organici ma ha una solubilità limitata in acqua. A causa della sua attività biologica, PGA2 è di interesse nella ricerca farmacologica, in particolare nel contesto della salute cardiovascolare e delle malattie infiammatorie. Tuttavia, la manipolazione e l'uso richiedono cautela a causa dei suoi potenti effetti biologici. Come molte prostaglandine, la sua sintesi e degradazione sono rigorosamente regolate all'interno dei sistemi biologici, evidenziando la sua importanza nel mantenimento dell'omeostasi.

Formula: C₂₀H₃₀O₄

InChI: InChI=1/C20H30O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h4,7,12-18,21H,2-3,5-6,8-11H2,1H3,(H,23,24)/b7-4-,14-12+/t16-,17-,18+/m0/s1

InChI key: InChIKey=MYHXHCUNDDAEOZ-FOSBLDSVSA-N

SMILES: C(/C=C\CCCC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCCCC)O)C=CC1=O

Sinonimi:

• (+)-Prostaglandin A₂
• (15S)-PGA₂
• (5Z,13E,15S)-15-hydroxy-9-oxoprosta-5,10,13-trien-1-oic acid
• 15(S)-Hydroxy-9-oxo-5-cis-10,13-trans-prostatrienoic acid
• 15(S)-Hydroxy-9-oxo-5-cis-10,13-trans-prostenoic acid
• 15(S)-Prostaglandin A₂
• 15-Hydroxy-9-Oxoprosta-5,10,13-Trien-1-Oic Acid
• 15α-Hydroxy-9-oxo-cis-5,10,trans-13-prostatrienecarboxylic acid
• 15α-Hydroxy-9-oxo-cis-5,10,trans-13-prostatrienoic acid
• 5,6-cis-PGA₂
• 5-Heptenoic acid, 7-[2-(3-hydroxy-1-octenyl)-5-oxo-3-cyclopenten-1-yl]-
• Medullin
• NSC 165561
• PGA₂
• Prosta-5,10,13-trien-1-oic acid, 15-hydroxy-9-oxo-, (5Z,13E,15S)-
• Prostaglandin A2 solution
• Prostaglandin A2
• (5Z)-7-[(1R,2S)-2-[(1E,3S)-3-Hydroxy-1-octenyl]-5-oxo-3-cyclopenten-1-yl]-5-heptenoic acid
• pga(sup2)
• 7-(2-(3-hydroxy-1-octenyl)-5-oxo-3-cyclopenten-1-yl)-5-heptenoicaci
• (5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5,10,13-trien-1-oic acid, PGA2
• 5,6-cis-pga(sup2)
• prostaglandina(sup2)
• (+)-prostaglandina(sup2)
• 9-OXO-15S-HYDROXY-PROSTA-5Z,10,13E-TRIEN-1-OIC ACID
• prostaglandin A(2) solution
• (155)-pga2
• PGA2 (Prostaglandin A2)
• PGA2
• 15-hydroxy-9-oxo-,(5z,13e,15s)-prosta-10-13-trien-1-oicacid
• Prostaglandin A2 solution,(5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5,10,13-trien-1-oic acid, PGA2
• (5Z,13E,15S)-15-Hydroxy-9-oxo-5,10,13-prostatrien-1-oic acid
• PROSTAGLANDINS A2

Prosta-5,10,13-trien-1-oicacid, 15-hydroxy-9-oxo-, (5Z,13E,15S)-

CAS: 13345-50-1

Formula: C₂₀H₃₀O₄

Purezza: 98%

Colore e forma: Liquid

Peso molecolare: 334.4498

Ref: IN-DA0080H8

Dinoprostone EP Impurity D (Prostaglandin A2)

CAS: 13345-50-1

Formula: C₂₀H₃₀O₄

Peso molecolare: 334.46

Ref: 4Z-D-250002

Prostaglandin A2

Prodotto controllato

CAS: 13345-50-1

Applications Prostaglandin A2 is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. Prostaglandin A2 is generally not present in mammals. Prostaglandin A2 has low biological potency in most bioassays, but it does show some antiviral/antitumor activity. Prostaglandin A2 has also been shown to act as a vasodilator with natriuretic properties.
References Stenson, W., et al.: J. Immunol., 124, 2100 (1980), Bray, M., et al.: Prostaglandins, 22, 213 (1981), Funk, C., et al.: Science, 294, 1871 (2001), Newman, J., et al.: J. Lipid Res., 43, 1563 (2002), Blaho, V., et al.: J. Biol. Chem., 284, 21599 (2009),

Formula: C₂₀H₃₀O₄

Colore e forma: Neat

Peso molecolare: 334.45

Ref: TR-P838550

Prostaglandin A6

CAS: 13345-50-1

Prostaglandin A6 is a lipid mediator that is involved in the regulation of many physiological and pathological processes. It has been shown to inhibit the activity of ion channels, increase the permeability of cell membranes, and activate G protein-coupled receptors. Prostaglandin A6 has been extensively used as an inhibitor in research tools for studying cell biology, peptides, pharmacology, ligand binding, and protein interactions. In addition, prostaglandin A6 is a potent activator of G protein-coupled receptors that are found in cardiovascular tissues. This compound also inhibits platelet aggregation and activates vasodilatory pathways.

Formula: C₂₀H₃₀O₄

Purezza: Min. 95%

Peso molecolare: 334.4 g/mol

Ref: 3D-BP180569

Dinoprostone EP Impurity D

CAS: 13345-50-1

Formula: C₂₀H₃₀O₄

Peso molecolare: 334.5

Ref: ST-EA-CP-D117004

Prostaglandin A2

CAS: 13345-50-1

PGA2 is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. It is generally not present in mammals. PGA2 has low biological potency in most bioassays, but it does show some antiviral/antitumor activity.[1] At a 25 uM concentration, PGA2 blocks the cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase .[2] It has also been shown to act as a vasodilator with natriuretic properties.[3]

Formula: C₂₀H₃₀O₄

Colore e forma: Solid

Peso molecolare: 334.45

Ref: TM-T36542