CAS 1334763-90-4

Aib-1 trifluoroacetate

CAS: 1334763-90-4

Aib-1 is a selective inhibitor of the ion channels TRPC1 and TRPC4. It has been shown to inhibit ligand-induced activation of these channels in cell lines expressing the respective channel. Aib-1 is a potent activator of the G protein-coupled receptor TGR5, which is also expressed in cells. The ligand for this receptor is unknown. Aib-1 binds to the extracellular domain of its target receptors and inhibits their function by blocking ionic conductance through the channels. Aib-1 also binds to peptides (e.g., anti-beta amyloid) and antibodies (e.g., anti-phosphorylated tau). Aib-1 trifluoroacetate is a high purity research tool used in Cell Biology, Pharmacology, and Ion Channels research fields. CAS No: 1334763-90-4

Formula: C₃₃H₃₇N₅O₆

Purezza: Min. 95%

Peso molecolare: 599.7 g/mol

Ref: 3D-JDC76390