CAS 134-63-4
:Cloridrato di (-)-Lobelina
Descrizione:
Cloridrato di (-)-Lobelina è un composto chimico noto principalmente per il suo utilizzo in farmacologia e come potenziale agente terapeutico. È un alcaloide derivato dalla pianta Lobelia inflata, comunemente nota come tabacco indiano. Questo composto presenta una gamma di attività biologiche, inclusi effetti sul sistema nervoso centrale, dove può agire come stimolante o depressore a seconda della dose e del contesto. Cloridrato di (-)-Lobelina è caratterizzato dalla sua natura chirale, con il "(-)" che indica la sua stereochimica specifica, cruciale per la sua attività biologica. La forma di sale cloridrato ne migliora la solubilità in acqua, rendendolo più adatto per applicazioni farmaceutiche. Oltre ai suoi potenziali usi terapeutici, la (-)-Lobelina è stata studiata per i suoi effetti sulla dipendenza da nicotina e come stimolante respiratorio. Tuttavia, il suo utilizzo è soggetto a scrutinio normativo a causa di preoccupazioni relative alla sicurezza e all'efficacia. In generale, Cloridrato di (-)-Lobelina è un composto di interesse sia in chimica medicinale che in farmacologia, con ricerche in corso sulle sue varie applicazioni.
Formula:C22H27NO2·ClH
InChI:InChI=1S/C22H27NO2.ClH/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18;/h2-7,9-12,19-21,24H,8,13-16H2,1H3;1H/t19-,20+,21-;/m0./s1
InChI key:InChIKey=MKMYPTLXLWOUSO-NFQNBQCWSA-N
SMILES:C([C@H](O)C1=CC=CC=C1)[C@H]2N(C)[C@@H](CC(=O)C3=CC=CC=C3)CCC2.Cl
Sinonimi:- (-)-α-Lobeline hydrochloride
- 2-((2R,6S)-6-((S)-2-Hydroxy-2-Phenylethyl)-1-Methylpiperidin-2-Yl)-1-Phenylethanone Hydrochloride
- 2-(6-(2-Hydroxy-2-Phenethyl)-1-Methyl-2-Piperidyl)Acetophenone Hydrochloride
- 2-[6-(2-Hydroxy-2-Phenylethyl)-1-Methylpiperidin-2-Yl]-1-Phenylethanone Hydrochloride (1:1)
- 2-{(2R,6S)-6-[(2R)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone hydrochloride
- 2-{(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone
- 2-{(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone hydrochloride (1:1)
- Butane-1,4-Diyl Dimethanesulfonate
- Ethanone, 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride
- Ethanone, 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride (1:1)
- Ethanone, 2-[6-(2-hydroxy-2-phenylethyl)-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride, [2R-[2α,6α(S*)]]-
- Lobelin hydrochloride
- Lobeline HCL
- Lobron
- Vuf 10751
- Zoolobelin
- alpha-Lobeline hydrochloride
- (-)-Lobeline hydrochloride
- Lobeline hydrochloride
- Lobeline, hydrochloride
- ALPHA-LOBELIN HCL
- 2-(6-(beta-hydroxyphenethyl)-1-methyl-2-piperidyl)-acetophenonhydrochlor
- A-LOBELINE HCL
- 2-(6-[2-HYDROXY-2-PHENYLETHYL]-1-METHYL-2-PIPERIDINYL)-1-PHENYLETHANONE HYDROCHLORIDE
- 2-(6-[2-Hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl)-1-phenylethanone, L-Lobeline, Hydrochloride
- LOBELINE HCL, A-
- 2-[6-(.beta.-hydroxyphenethyl)-1-methyl-2-piperidyl]-,hydrochloride,(-)-Acetophenone
- 2-[(2r,6s)-6-[(2s)-2-hydroxy-2-phenyl-ethyl]-1-methyl-2-piperidyl]-1-phenyl-ethanone hydrochloride
- 2-[6-(2-HYDROXY-2-PHENETHYL)-1-METHYL-2-PIPERIDYL]ACETOPHENONE HCL
- Apolipoprotein B (LDL), Sheep anti-Human, Guinea pig, Swine (NO X w/Bovine, Horse, Dog, Cat, Rabbit, Chicken, Goat, Mouse, Rat)
- Lobelinhydrochloride
- L-LOBELINE HYDROCHLORIDE
- [2-[(2R,6S)-6-[(2S)-2-HYDROXYPHENETHYL]]-1-METHYL-2-PIPERIDYL]ACETOPHENONE HYDROCHLORIDE
- Vedi altri sinonimi
Ordinare per
Purezza (%)
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100
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90
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95
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11 prodotti.
Lobeline hydrochloride
CAS:Formula:C22H28ClNO2Purezza:98%Colore e forma:SolidPeso molecolare:373.9162Lobeline hydrochloride
CAS:Lobeline hydrochloride (α-Lobeline hydrochloride) is a nicotinic receptor agonist, acting as an effective antagonist at both α4β2 and α3β2 neuronal nicotinicFormula:C22H27NO2·HClPurezza:99.31% - 99.43%Colore e forma:Rosettes Of Slender Needles From Alc White To Off-White SolidPeso molecolare:373.92Lobeline HCl
CAS:Formula:C22H27NO2·HClColore e forma:White To Off-White SolidPeso molecolare:337.46 36.46(-)-Lobeline hydrochloride
CAS:Formula:C22H27NO2·HClPurezza:≥ 97.0%Colore e forma:White to off-white powderPeso molecolare:373.92Lobeline Hydrochloride
CAS:Prodotto controllatoFormula:C22H27NO2·ClHColore e forma:NeatPeso molecolare:373.92a-Lobeline hydrochloride
CAS:a-Lobeline hydrochloride is an alkaloid-based compound, which is primarily derived from the Lobelia plant species. It functions as a nicotinic acetylcholine receptor antagonist and dopamine transporter inhibitor, interacting with the central nervous system to modulate neurotransmitter activities. This compound has historically been explored for its potential in nicotine addiction treatment due to its ability to inhibit the reuptake of dopamine, thereby influencing reward pathways associated with addiction.
Formula:C22H28ClNO2Purezza:Min. 95%Colore e forma:White/Off-White SolidPeso molecolare:373.92 g/mol2-(6-(2-Hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone hydrochloride
CAS:Formula:C22H28ClNO2Purezza:98%Peso molecolare:373.92alpha-Lobeline Hydrochcloride
CAS:Prodotto controllatoApplications A neuronal nicotinic acetylcholine receptor agonist. A CNS stimulant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Damaj, M.I., et al.: J. Pharmacol. Exp. Ther., 282, 410 (1997), Toth, P.T., et al.: Eur. J. Pharmacol., 363, 75 (1998), Flammia, D., et al.: J. Med. Chem., 42, 3726 (1999), Dwoskin, P.A., et al.: Biochem. Pharmacol., 63, 89 (2002),Formula:C22H27NO2·ClHColore e forma:NeatPeso molecolare:373.92
