CAS 13422-55-4

Metilcobalamina

Descrizione:

Metilcobalamina, con il numero CAS 13422-55-4, è una forma biologicamente attiva della vitamina B12, nota anche come cobalamina. È una vitamina solubile in acqua che svolge un ruolo cruciale in vari processi fisiologici, inclusa la sintesi del DNA, la formazione dei globuli rossi e la funzione neurologica. Metilcobalamina è caratterizzata dalla sua struttura ad anello corrin contenente cobalto, essenziale per la sua attività biologica. Viene spesso utilizzata come integratore alimentare ed è particolarmente importante per le persone con carenza di vitamina B12, che può portare ad anemia e problemi neurologici. Metilcobalamina è noto per la sua capacità di attraversare la barriera emato-encefalica, rendendolo benefico per la salute neurologica. In termini di stabilità, è sensibile alla luce e al calore, il che può influenzare la sua potenza. La sostanza viene tipicamente somministrata tramite integratori orali o iniezioni, a seconda delle esigenze dell'individuo. In generale, Metilcobalamina è vitale per mantenere una funzione nervosa sana e processi metabolici nel corpo.

Formula: C₆₃H₉₁CoN₁₃O₁₄P

InChI: InChI=1S/C62H90N13O14P.CH3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H3;/q;-1;+3/p-2/t31-,34-,35-,36-,37+,41-,52?,53-,56+,57+,59-,60+,61+,62+;;/m1../s1

InChI key: InChIKey=ZFLASALABLFSNM-FGIXMQGJSA-L

SMILES: [CH3-][Co+3]1234[N]=5[C@@]6(C)[C@]7([N-]1C([C@@](C)([C@H]7CC(N)=O)CCC(=O)NC[C@@H](C)OP(=O)([O-])O[C@H]8C(O)([C@@H](N9C=[N]2C=%10C9=CC(C)=C(C)C%10)O[C@@H]8CO)[H])=C(C)C%11=[N]3C(=CC%12=[N]4C(=C(C)C5[C@@H](CCC(N)=O)[C@@]6(CC(N)=O)C)[C@](CC(N)=O)(C)[C@@H]%12CCC(N)=O)C(C)(C)[C@@H]%11CCC(N)=O)[H]

Sinonimi:

• Algobaz
• Co-Methylcobalamin
• Cobalamin, Co-methyl-
• Cobinamide, Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole
• Cobinamide, Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole
• Cobinamide, Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole
• Cobinamide, Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole
• Cobinamide, Co-methyl derivative, hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole
• Cobinamide, Co-methyl-, dihydrogen phosphate (ester), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³)
• Hitocobamin M
• MeCbl
• Mecobalamin
• Mecobalamina
• Mecobalamine
• Methycobal
• Methyl cobalamine
• Methyl vitamin B12
• Methyl vitamin B₁₂
• Methyl-5,6-dimethylbenzimidazolylcobalamin
• Methyl-B12
• Methyl-B₁₂
• Methylcob(III)alamin
• Methylcobalamin
• Methylcobaz

Methylcobalamin Hydrate

CAS: 13422-55-4, 288315-09-3

Formula: C₆₃H₉₁CoN₁₃O₁₄P·xH₂O

Purezza: >98.0%(N)

Colore e forma: Red to Dark red to Brown powder to crystal

Peso molecolare: 1,344.40 (as Anhydrous)

Ref: 3B-M2742

Methylcobalamin

CAS: 13422-55-4

Vitamin b12 (cyanocobalamin and related compounds with vitamin b12 activity) and its derivatives

Formula: C₆₃H₉₁CoN₁₃O₁₄P

Colore e forma: Dark Red Powder

Peso molecolare: 1343.5878

Ref: 45-1424550

Methylcobalamin

CAS: 13422-55-4

Formula: C₆₃H₉₁CoN₁₃O₁₄P

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 1344.3823

Ref: IN-DA003S3I

Methylcobalamin-d3

CAS: 13422-55-4

Formula: C₆₃H₈₈D₃CoN₁₃O₁₄P

Peso molecolare: 1347.42

Ref: 4Z-V-035018

Methylcobalamin hydrate

CAS: 13422-55-4

Formula: C₆₃H₉₁CoN₁₃O₁₄P·xH₂O

Purezza: 98.0 - 102.0 % (dried basis)

Colore e forma: Dark red crystalline powder or crystals

Peso molecolare: 1344.41 (anhydrous)

Ref: 7W-GV9033

Methylcobalamin

CAS: 13422-55-4

Formula: C₆₃H₉₁CoN₁₃O₁₄P

Colore e forma: Neat

Peso molecolare: 1344.38

Ref: 04-C15084870

Methylcobalamin

CAS: 13422-55-4

Methylcobalamin, a B12 form, aids homocysteine metabolism; treats nutritional issues, Alzheimer's, and rheumatoid arthritis.

Formula: C₆₃H₉₁CoN₁₃O₁₄P

Purezza: 98% - 98.23%

Colore e forma: Solid

Peso molecolare: 1344.38

Ref: TM-T3136

Methylcobalamin-13C-d3

CAS: 13422-55-4

Formula: CC₆₂H₈₈D₃CoN₁₃O₁₄P

Peso molecolare: 1348.42

Ref: 4Z-V-035006

Mecobalamin RS

CAS: 13422-55-4

Colore e forma: Dark Red

Ref: 2K-1159000021

Mecobalamin-d3

Prodotto controllato

CAS: 13422-55-4

Stability Light Sensitive
Applications Isotope labelled Mecobalamin (M202800), one of the biologically active forms of vitamin B12; differing only by the substitution of a methyl for the cyano group. Coenzyme required in the biosynthesis of methionine. Vitamin (hematopoietic).
References Kisliuk, R.L., Biochem. J., 75, 467 (1960), Guest, J.R., et al.: Nature, 195, 340 (1962), Dolphin, D., et al.: Methods Enzymol., 18, 34 (1971), Beck, W.S., et al.: Am. J. Hematol., 34, 83 (1990),

Formula: C₆₃H₈₈D₃CoN₁₃O₁₄P

Colore e forma: Dark Red

Peso molecolare: 1347.4

Ref: TR-M202802

Mecobalamin

CAS: 13422-55-4

Stability Light Sensitie
Applications One of the biologically active forms of vitamin B12; differing only by the substitution of a methyl for the cyano group. Coenzyme required in the biosynthesis of methionine. Vitamin (hematopoietic).
References Kisliuk, R.L., Biochem. J., 75, 467 (1960), Guest, J.R., et al.: Nature, 195, 340 (1962), Dolphin, D., et al.: Methods Enzymol., 18, 34 (1971), Beck, W.S., et al.: Am. J. Hematol., 34, 83 (1990),

Formula: C₆₃H₉₁CoN₁₃O₁₄P

Colore e forma: Neat

Peso molecolare: 1344.38

Ref: TR-M202800

Mecobalamin

CAS: 13422-55-4

Mecobalamin is a form of vitamin B12 that is used to treat bowel disease. It binds to the target enzymes methionine synthase and cystathionine beta-synthase, which are involved in the synthesis of methionine and cysteine respectively. Mecobalamin has been shown to be effective in treating Crohn's disease when given as a low-dose therapy. Mecobalamin also has demonstrated therapeutic effects in ulcerative colitis, but had no effect on patients with non-ulcerative colitis. Mecobalamin was well tolerated at the doses tested and did not produce any significant changes in blood cell counts or liver enzyme activities.
Mecobalamin is not absorbed orally, so it is given by injection or intravenously. The drug can be injected subcutaneously, intramuscularly, or intravenously.

Formula: C₆₃H₉₁CoN₁₃O₁₄P

Purezza: Min. 95%

Colore e forma: Red Powder

Peso molecolare: 1,344.38 g/mol

Ref: 3D-FM25030

Vitamin B12a (B12 Analog) ExiPlus, Multi-Compendial, 98%-102%

CAS: 13422-55-4

Formula: C₆₃H₉₁CoN₁₃O₁₄P

Purezza: 98 - 102%

Colore e forma: Dark red, Crystalline powder, Clear, Red

Peso molecolare: 1355.38

Ref: SR-79446

Mecobalamin-13CD3

Prodotto controllato

CAS: 13422-55-4

Formula: C₆₂CH₈₈D₃CoN₁₃O₁₄P

Colore e forma: Neat

Peso molecolare: 1348.42

Ref: TR-M202801