CAS 134523-00-5
:Atorvastatina
Descrizione:
Atorvastatina è un agente sintetico per la riduzione dei lipidi che appartiene alla classe delle statine, utilizzato principalmente per gestire l'iperlipidemia e ridurre il rischio di malattie cardiovascolari. Il suo meccanismo d'azione implica l'inibizione della HMG-CoA reduttasi, un enzima critica nella via di biosintesi del colesterolo, portando a livelli ridotti di lipoproteine a bassa densità (LDL) e colesterolo totale nel flusso sanguigno. Atorvastatina è caratterizzato dalla sua formula molecolare, che include atomi di carbonio, idrogeno, azoto e ossigeno, riflettendo la sua struttura complessa. Il composto è tipicamente somministrato per via orale e presenta una buona biodisponibilità. Viene metabolizzato principalmente nel fegato, con una parte significativa che subisce il metabolismo di primo passaggio. Gli effetti collaterali comuni possono includere dolore muscolare, alterazioni degli enzimi epatici e disturbi gastrointestinali. Atorvastatina è spesso prescritto insieme a modifiche dello stile di vita, come dieta ed esercizio fisico, per migliorare la sua efficacia nella riduzione dei livelli di colesterolo. I suoi benefici terapeutici, insieme ai potenziali rischi, richiedono un attento monitoraggio da parte dei professionisti sanitari durante il trattamento.
Formula:C33H35FN2O5
InChI:InChI=1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/t26-,27-/m1/s1
InChI key:InChIKey=XUKUURHRXDUEBC-KAYWLYCHSA-N
SMILES:C(NC1=CC=CC=C1)(=O)C=2C(=C(N(CC[C@H](C[C@H](CC(O)=O)O)O)C2C(C)C)C3=CC=C(F)C=C3)C4=CC=CC=C4
Sinonimi:- (3R,5R)-7-[2-(4-Fluorophenyl)-3-Phenyl-4-(Phenylcarbamoyl)-5-Propan-2-Yl-Pyrrol-1-Yl]-3,5-Dihydroxy-Heptanoic Acid
- (3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid
- (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
- (3S,5S)-7-[2-(4-Fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid
- (3S,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
- (βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid
- (βR,δR)-2-(p-Fluorophenyl)-β,δ-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoic acid
- 1H-Pyrrole-1-Heptanoic Acid
- 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (βR,δR)-
- 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (βR,δR)-rel-
- 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, [R-(R*,R*)]-
- 1H-pyrrole-1-heptanoate, 3-benzoyl-5-(4-fluorophenyl)-β,δ-dihydroxy-2-(1-methylethyl)-4-phenyl-, calcium salt, (betaR,deltaR)- (1:1)
- Atavastatin
- Atofast
- Atorcor
- Atorfit 20
- Atorin
- Atoris
- Atorvastatin Acid
- Atorvox
- Atrox
- Cardyl
- Lipilou
- Lipinon
- Statofilm
- calcium bis{(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate}
- Vedi altri sinonimi
Ordinare per
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9 prodotti.
Atorvastatin Calcium Salt Trihydrate
CAS:Formula:C66H68CaF2N4O10·3H2OPurezza:>98.0%(HPLC)(N)Colore e forma:White to Almost white powder to crystalPeso molecolare:1,209.41(3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid
CAS:Formula:C33H35FN2O5Purezza:98%Colore e forma:SolidPeso molecolare:558.6398Atorvastatin
CAS:Formula:C33H35FN2O5Purezza:≥ 98%Colore e forma:White to off-white crystalline powderPeso molecolare:558.64Des-(N-Phenyl)Carbamoyl Atorvastatin Calcium Salt
CAS:Prodotto controllatoFormula:(C26H29FNO4)•CaColore e forma:NeatPeso molecolare:2(438.52) + (40.08)Atorvastatin
CAS:<p>Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.</p>Formula:C33H35FN2O5Purezza:99.37% - 99.69%Colore e forma:SolidPeso molecolare:558.64(3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid
CAS:Formula:C33H35FN2O5Purezza:98.0%Colore e forma:Solid, White powderPeso molecolare:558.653-Fluoro Atorvastatin Sodium Salt-d5
CAS:Prodotto controllatoFormula:C33D5H29FN2NaO5Colore e forma:NeatPeso molecolare:585.6523-Fluoro Atorvastatin Sodium Salt
CAS:Prodotto controllato<p>Applications 3-Fluoro Atorvastatin Sodium Salt is an impurity of Atorvastatin (A791750, Ca Salt); a selective, competitive HMG-CoA reductase inhibitor and the only drug in its class specifically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Formula:C33H34FN2NaO5Colore e forma:NeatPeso molecolare:580.62Atorvastatin acid
CAS:<p>Atorvastatin acid is a pharmaceutical compound belonging to the class of statins, which is a synthetic derivative of fungal metabolites. It functions as an HMG-CoA reductase inhibitor, playing a critical role in the cholesterol biosynthesis pathway. By inhibiting this key enzyme, atorvastatin acid effectively reduces the conversion of HMG-CoA to mevalonate, a precursor of cholesterol, thus lowering overall cholesterol levels in the bloodstream.</p>Formula:C33H35FN2O5Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:558.64 g/mol
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