CAS 134523-03-8

Atorvastatina calcio

Descrizione:

Atorvastatina calcio è un composto farmaceutico utilizzato principalmente come agente ipolipemizzante per gestire l'iperlipidemia e ridurre il rischio di malattie cardiovascolari. Appartiene alla classe di farmaci noti come statine, che funzionano inibendo l'enzima HMG-CoA reduttasi, un attore chiave nella biosintesi del colesterolo nel fegato. Questa azione porta a una diminuzione del colesterolo a lipoproteine a bassa densità (LDL) e dei trigliceridi, mentre aumenta i livelli di colesterolo a lipoproteine ad alta densità (HDL). L'atorvastatina viene tipicamente somministrata per via orale ed è ben assorbita nel tratto gastrointestinale. La sua solubilità è influenzata dal pH, con una migliore solubilità in condizioni acide. Il composto è caratterizzato dalla sua formula molecolare, che riflette la sua struttura complessa, ed esiste come sale di calcio per migliorare la sua stabilità e biodisponibilità. Gli effetti collaterali comuni possono includere dolore muscolare, alterazioni degli enzimi epatici e disturbi gastrointestinali. Come per tutti i farmaci, l'atorvastatina deve essere utilizzata sotto supervisione medica, considerando le potenziali interazioni con altri farmaci e i profili di salute individuali dei pazienti.

Formula: C₆₆H₆₈Ca₂F₂N₄O₁₀

InChI: InChI=1/2C33H35FN2O5.2Ca.2H/c2*1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;;;;/h2*3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);;;;/q;;;+2;;/p-2/t2*26-,27-;;;;/m11..../s1/r2C33H35FN2O5.CaH2.Ca/c2*1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;;/h2*3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);1H2;/q;;;+2/p-2/t2*26-,27-;;/m11../s1

InChI key: InChIKey=BWFCZHDTTAYGNN-CNZCJKERSA-N

SMILES: C(NC1=CC=CC=C1)(=O)C=2C(=C(N(CC[C@H](C[C@H](CC(O)=O)O)O)C2C(C)C)C3=CC=C(F)C=C3)C4=CC=CC=C4.[Ca]

Sinonimi:

• (3R,5R)-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl)Pyrrol-1-yl]-3,5-Dihydroheptanoic Acid,calcium salt
• (3R,5R)-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl)Pyrrol-1-yl]-3,5�CDihydroheptanoic Acid,calcium salt
• (3R,5R)-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl)Pyrrol-1-yl]-3,5�CDihydroheptanoic Acid,calcium salt(L-4)
• (R-(R*,R*))-, Atorvastatin calcium
• 1H-Pyrrole-1-Heptanoicacid,Beta,Delta-Dihydroxy-2-(4-Fluorophenyl)-5-(1-Methy Calciumsalt(2:1),(R-(R*,R*))-Lethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)
• 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-calcium salt (2: 1), (R-(R*,R*))-
• 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt (2:1), (βR,δR)-
• 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt (2:1), [R-(R*,R*)]-
• 1H-Pyrrole-1-heptanoic acid,beta,delta-dihydroxy-2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-calcium salt (2: 1)
• Atocor
• Atoraz
• Atorvastatin Ca
• Atorvastatin Calcium Anhydrous
• Atorvastatin Calsium
• Atorvastatin calcium (USAN)
• Atorvastatin calcium salt
• Atorvastatin hemicalcium
• Atorvastatin hemicalcium salt
• Atorvastatincalcuim
• Beta,Delta-Dihydroxy-2-(4-Fluorophenyl)-5-(1-Methylethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)-Calcium Salt(2:1)
• C08078
• Calcium (betaR,deltaR)-2-(p-fluorophenyl)-beta,delta-dihydroxy-5-isopr opyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoate (1:2)
• Ci-981
• D00887
• Delta-Dihydroxy-2-(4-Fluorophenyl)-5-(1-Methylethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)-Betcalci1H-Pyrrole-1-Heptanoicaci
• Drg-0321
• L-4
• Lipibec
• Lipitor
• Lipitor (TN)
• Lorvast
• Lowlip
• Ls-136974
• Pd 134298-38A
• Pd134298-38A
• Prevencor
• Rotacor
• Sortis
• Storvas
• Tahor
• Torvast
• Ym-548
• [R-(R*, R*)]-7-[2-(4-Fluorophenyl)-5-(1-Methylethyl)-3-Phenyl-4-(Phenylaminocarbonyl)-1H-Pyrrol-1-Yl]-3,5-Dihydroxy-Heptanoic Acid Calcium Salt
• calcium (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-p ropan-2-yl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate
• Atorvastatin calcium
• calciumsalt(2:1),(r-(r*,r*))-lethyl)-3-phenyl-4-((phenylamino)carbonyl)
• (3R ,5R )-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl) Pyrrol-1-yl]-3 ,5-Dihydroheptanoic Acid, calcium salt (2:1) Trihydrate
• 3R ,5R )-7-[2-(4-Fluorophenyl)-5-Isopropyl-3-Phenyl-4-(Pheynylcarbamoyl) Pyrrol-1-yl]-3 ,5 ydroheptanoic Acid, calcium salt (2:1) Trihydrate
• 1h-pyrrole-1-heptanoicacid,beta,delta-dihydroxy-2-(4-fluorophenyl)-5-(1-methy
• Atrovastatin calcium
• (bR,dR)-2-(4-Fluorophenyl)-b,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid
• ATORVASTATINE CADIUM
• 3S,5S-Atorvastatin
• Atorvastatin Calclum
• ATORVASTATIN CALCIUM MM(CRM STANDARD)

Atorvastatin Calcium Salt Trihydrate

CAS: 134523-00-5, 134523-03-8, 344423-98-9

Formula: C₆₆H₆₈CaF₂N₄O₁₀·3H₂O

Purezza: >98.0%(HPLC)(N)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 1,209.41

Ref: 3B-A2476

Atorvastatin Calcium

CAS: 134523-03-8

Colore e forma: Neat

Ref: 61-FOR0400.00

Atorvastatin calcium

CAS: 134523-03-8

Atorvastatin calcium

Formula: C₆₆H₆₈CaF₂N₄O₁₀

Purezza: 95.1%

Colore e forma: White

Peso molecolare: 1154.45294

Ref: 47-1267

1H-Pyrrole-1-heptanoicacid,2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-,calciumsalt(2:1),(βR,δR)-

CAS: 134523-03-8

Formula: C₆₆H₆₈CaF₂N₄O₁₀

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 1155.3417

Ref: IN-DA00368S

Atorvastatin calcium salt

CAS: 134523-03-8

Formula: C₃₃H₃₄FN₂O₅·5Ca·5H₂O

Purezza: 98.0 - 102.0 % (anhydrous basis)

Colore e forma: White to almost white crystalline powder

Peso molecolare: 604.69

Ref: 7W-GP5009

Atorvastatin Calcium Salt

CAS: 134523-03-8

Formula: C₃₃H₃₄FN₂O₅·5Ca

Colore e forma: White To Off-White Solid

Peso molecolare: 557.65 0.5*40.08

Ref: 4Z-A-121

Atorvastatin hemicalcium salt (Standard)

CAS: 134523-03-8

Atorvastatin hemicalcium salt (Standard) is the standard substance of Atorvastatin hemicalcium salt, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an HMG-CoA reductase inhibitor with oral activity. Atorvastatin hemicalcium salt is used to lower cholesterol.

Formula: C₃₃H₃₄FN₂O₅Ca

Colore e forma: White Crystalline Powder

Peso molecolare: 577.67

Ref: TM-TMSM-0471

Atorvastatin calcium

CAS: 134523-03-8

Formula: C₃₃H₃₄FN₂O₅·Ca

Colore e forma: Neat

Peso molecolare: 1155.34

Ref: 04-C10318000

Atorvastatin Calcium

Prodotto controllato

CAS: 134523-03-8

Formula: C₃₃H₃₄FN₂O₅·Ca

Colore e forma: Neat

Peso molecolare: 1155.34

Ref: 86-MM0400.00

Atorvastatin hemicalcium salt

CAS: 134523-03-8

Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.

Formula: C₃₃H₃₄FN₂O₅Ca

Purezza: 99.27% - >99.99%

Colore e forma: White Crystalline Powder

Peso molecolare: 577.67

Ref: TM-T3116

Atorvastatin Impurity 61

CAS: 134523-03-8

Formula: C₄₀H₄₇FN₂O₆

Colore e forma: White To Off-White Solid

Peso molecolare: 670.82

Ref: 4Z-A-12102

Atorvastatin Calcium Salt

Prodotto controllato

CAS: 134523-03-8

Applications A selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
References Zhao Y et al. Medicine (Baltimore). 2017 Feb;96(7):e6104.Wu X et al. Carcinogenesis. 2017 Feb 16Sepehri Z et al. PLoS One. 2017 Feb 13;12(2):e0172404

Formula: C₃₃H₃₄FN₂O₅·Ca

Colore e forma: White

Peso molecolare: 1155.34

Ref: TR-A791750

Atorvastatin Calcium Salt

CAS: 134523-03-8

Formula: C₃₃H₃₄FN₂O₅·Ca

Ref: TR-TRC-A791750

Atorvastatin calcium salt - Bio-X ™

CAS: 134523-03-8

Atorvastatin is an HMG-CoA reductase inhibitor that is used to lower lipid levels and to aid in the management of cardiovascular diseases. Animal studies have demonstrated that this drug has vasculoprotective properties.

Formula: (C₃₃H₃₅FN₂O₅)₂•Ca

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 1,157.36 g/mol

Ref: 3D-BA164226

Atorvastatin calcium

CAS: 134523-03-8

HMG-CoA reductase inhibitor; anti-hypercholesterolemia agent

Formula: C₆₆H₆₈CaF₂N₄O₁₀

Purezza: Min. 97 Area-%

Colore e forma: White Powder

Peso molecolare: 1,155.34 g/mol

Ref: 3D-FA57652