CAS 137076-54-1

Tri-terz-butil 1,4,7,10-tetraazaciclododecano-tetraacetato

Descrizione:

Tri-terz-butil 1,4,7,10-tetraazaciclododecano-tetraacetato è un composto organico complesso caratterizzato dalla sua unica struttura ciclica e da molteplici gruppi funzionali. Presenta uno scheletro di tetraazaciclododecano, che consiste in un anello di 12 membri contenente quattro atomi di azoto, contribuendo alle sue proprietà chelanti. La presenza di quattro gruppi tert-butilici aumenta il suo ingombro sterico, influenzando la sua solubilità e reattività. I moieties di tetraacetato forniscono una funzionalizzazione aggiuntiva, consentendo potenziali interazioni con ioni metallici, rendendolo utile nella chimica di coordinazione. Questo composto è tipicamente sintetizzato attraverso reazioni organiche in più fasi, e la sua stabilità e solubilità possono variare a seconda del solvente e delle condizioni utilizzate. A causa della sua complessità strutturale, può presentare proprietà interessanti come il legame selettivo a determinati ioni metallici, che possono essere sfruttati in varie applicazioni, inclusa la catalisi e la scienza dei materiali. I dati di sicurezza e le precauzioni di manipolazione devono essere osservati, come per qualsiasi sostanza chimica, per mitigare i rischi associati al suo uso.

Formula: C₂₈H₅₂N₄O₈

InChI: InChI=1/C28H52N4O8/c1-26(2,3)38-23(35)19-30-12-10-29(18-22(33)34)11-13-31(20-24(36)39-27(4,5)6)15-17-32(16-14-30)21-25(37)40-28(7,8)9/h10-21H2,1-9H3,(H,33,34)

SMILES: CC(C)(C)OC(=O)CN1CCN(CCN(CCN(CC1)CC(=O)OC(C)(C)C)CC(=O)OC(C)(C)C)CC(=O)O

Sinonimi:

• [4,7,10-Tris(2-Tert-Butoxy-2-Oxoethyl)-1,4,7,10-Tetraazacyclododecan-1-Yl]Acetic Acid
• Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetate

Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetate

CAS: 137076-54-1

Formula: C₂₈H₅₂N₄O₈

Purezza: >97.0%(T)

Colore e forma: White to Gray to Red powder to crystal

Peso molecolare: 572.74

Ref: 3B-T2642

DOTA(OtBu)₃

CAS: 137076-54-1

t-Butyl ester-protected DOTA derivative allows the selective conjugation of the macrocyclic chelator to peptides during Fmoc-SPPS. DOTA forms highly stable chelates with radioactive isotopes of Ga,In,and Y, as well as with radionuclides of Lu, Gd, and other lanthanides.

Formula: C₂₈H₅₂N₄O₈

Purezza: 98.6%

Colore e forma: White Powder

Peso molecolare: 572.74

Ref: 01-4029066

1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 1,4,7-tris(1,1-dimethylethyl) ester

CAS: 137076-54-1

Formula: C₂₈H₅₂N₄O₈

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 572.7345

Ref: IN-DA0012TN

DOTA-tri(t-butyl ester)

CAS: 137076-54-1

DOTA-tri(t-butyl ester) is used to make G3 MRI contrast agents for MR angiography and tumor imaging.

Formula: C₂₈H₅₂N₄O₈

Colore e forma: Solid

Peso molecolare: 572.73

Ref: TM-T38783

Gadobutrol Impurity 87

CAS: 137076-54-1

Formula: C₂₈H₅₂N₄O₈

Peso molecolare: 572.74

Ref: 4Z-G-31111

DOTA-tris(tBu)ester

CAS: 137076-54-1

DOTA-tris(tBu)ester

Formula: C₂₈H₅₂N₄O₈

Purezza: 97%

Colore e forma: white to off-white solid

Peso molecolare: 572.73447g/mol

Ref: 54-OR904563

DOTA-tris (t-Bu ester) (~90%)

Prodotto controllato

CAS: 137076-54-1

Applications DOTA-tris (t-Bu ester), is a Bifunctional chelator, that can be used in the preparation of gadolinium complexes as MRI blood contrast agents.

Formula: C₂₈H₅₂N₄O₈

Purezza: ~90%

Colore e forma: Neat

Peso molecolare: 572.73

Ref: TR-D494855

2-(4,7,10-TRIS(2-TERT-BUTOXY-2-OXOETHYL)-1,4,7,10-TETRAAZACYCLODODECAN-1-YL)ACETIC ACID

CAS: 137076-54-1

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 572.7440186

Ref: 10-F792189

DOTA(tBu)3-OH

CAS: 137076-54-1

DOTA(tBu)3-OH is a Building Block that is used in peptide synthesis. It can be used as a condensation reagent or as a building block for the synthesis of peptides and antibodies. DOTA(tBu)3-OH is also an additive for labelling and building blocks for peptide synthesis. DOTA(tBu)3-OH is stable and not toxic to cells, making it useful in cell culture applications. It has been shown to react with the side chain amino groups of lysine residues on proteins, including antibody molecules.

Formula: C₂₈H₅₂N₄O₈

Purezza: Min. 95%

Peso molecolare: 572.73 g/mol

Ref: 3D-DTB-5003-PI

DOTA-Tris(tBu)

CAS: 137076-54-1

Formula: C₂₈H₅₂N₄O₈

Peso molecolare: 572.74

Ref: ST-EA-CP-G39012

Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate

CAS: 137076-54-1

Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate (TBA) is a gadolinium chelate that is used as a contrast agent in magnetic resonance imaging. TBA binds to the malignant cells and shows an increase in uptake of the gadolinium contrast agent. TBA has been shown to be effective in the diagnosis of cancerous brain tissue and is also able to detect cancer cells in animals. TBA has shown some efficacy against bacterial infection by binding to the cell membrane and inhibiting protein synthesis. It is also able to act synergistically with antibiotics such as penicillin or ampicillin to kill bacteria more effectively.

Formula: C₂₈H₅₂N₄O₈

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 572.73 g/mol

Ref: 3D-FT49920