CAS 13710-19-5

acido tolfenamico

Descrizione:

acido tolfenamico è un farmaco antinfiammatorio non steroideo (FANS) che appartiene alla classe dei derivati dell'acido antranilico. Viene utilizzato principalmente per le sue proprietà analgesiche e antinfiammatorie, rendendolo efficace nel trattamento del dolore e dell'infiammazione associati a varie condizioni. La struttura chimica di acido tolfenamico presenta un gruppo acido carbossilico e un anello aromatico, che contribuiscono alla sua attività farmacologica. Mostra una solubilità moderata in acqua ed è più solubile nei solventi organici, riflettendo la sua natura lipofila. acido tolfenamico agisce inibendo le enzimi cicloossigenasi (COX), riducendo così la sintesi delle prostaglandine, che sono mediatori dell'infiammazione e del dolore. La sostanza viene tipicamente somministrata per via orale ed è nota per il suo inizio d'azione relativamente rapido. Inoltre, è stata studiata per il suo potenziale utilizzo in medicina veterinaria, in particolare nel trattamento del dolore negli animali. Come altri FANS, può avere effetti collaterali, inclusi disturbi gastrointestinali, e deve essere usata con cautela in individui con determinate condizioni di salute.

Formula: C₁₄H₁₂ClNO₂

InChI: InChI=1/C14H12ClNO2/c1-9-11(15)6-4-8-12(9)16-13-7-3-2-5-10(13)14(17)18/h2-8,16H,1H3,(H,17,18)

InChI key: InChIKey=YEZNLOUZAIOMLT-UHFFFAOYSA-N

SMILES: N(C1=C(C(O)=O)C=CC=C1)C2=C(C)C(Cl)=CC=C2

Sinonimi:

• 1,2-Distearoyl-sn-glycero-3-phosphocholine, DSPC
• 2 (3-Chloro-2-Methylanilino)Benzoic Acid
• 2-((3-Chloro-2-Methylphenyl)Amino)-Benzoicaci
• 2-(3-Chloro-O-Toluidino)Benzoic Acid
• 2-[(3-Chloro-2-Methylphenyl)Amino]Benzoic Acid
• 2-[(4-Chloro-3-Methylphenyl)Amino]Benzoic Acid
• Anthranilic acid, N-(3-chloro-o-tolyl)-
• Benzoic acid, 2-[(3-chloro-2-methylphenyl)amino]-
• Clotam
• Gea 6414
• Gea6414
• Labotest-Bb Lt00772313
• Migea
• N-(2-Methyl-3-chlorophenyl)anthranilic acid
• N-(3-Chloro-o-tolyl)anthranilic acid
• N-(3-Chloro-ortho-tolyl) anthranilic acid
• Tolfedine
• Tolfenamate
• Tolfine
• n-(3-chloro-o-tolyl)-anthranilicacid
• Tolfenamic
• n-(3-chloro-o-tolyl)-anthranilicaci
• TOLFENAMIC ACID
• N-(3-CHLORO-2-METHYLPHENYL)ANTHRANILIC ACID
• 2 (3-Chloro-2-methylanilino)benzoic acid, 2-([3-Chloro-2-methylphenyl]amino)benzoic acid
• n-(2-methyl-3-chlorophenyl)anthranilicacid

Tolfenamic Acid

CAS: 13710-19-5

Formula: C₁₄H₁₂ClNO₂

Purezza: >97.0%(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 261.71

Ref: 3B-C2064

Tolfenamic acid, 99+%

CAS: 13710-19-5

Tolfenamic acid is a non-steroidal anti-inflammatory agent. It interferes with synthesis of -amyloid precursor protein, and thus A peptides, by promoting degradation of an essential transcription factor. It inhibits fMLP- and A23187-induced Ca2+ influx in human PMNL with an IC50 value of approximate

Formula: C₁₄H₁₂ClNO₂

Purezza: 99+%

Peso molecolare: 261.71

Ref: 02-J61256

Tolfenamic Acid

CAS: 13710-19-5

Colore e forma: Neat

Ref: 61-FOR3395.00

TOLFENAMIC ACID CRS

CAS: 13710-19-5

TOLFENAMIC ACID CRS

Formula: C₁₄H₁₂ClNO₂

Colore e forma: Added Modified

Peso molecolare: 261.7036

Ref: 41-Y0000154

2-[(3-chloro-2-methylphenyl)amino]benzoic acid

CAS: 13710-19-5

Formula: C₁₄H₁₂ClNO₂

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 261.7036

Ref: IN-DA003SAR

Tolfenamic Acid

CAS: 13710-19-5

Tolfenamic Acid (GEA 6414) is one of the class of non-steroidal anti-inflammatory drugs (NSAIDs). It is used to treat the symptoms of migraine.

Formula: C₁₄H₁₂ClNO₂

Purezza: 99.71% - 99.97%

Colore e forma: Solid

Peso molecolare: 261.70

Ref: TM-T0784

Tolfenamic Acid

CAS: 13710-19-5

Formula: C₁₄H₁₂ClNO₂

Colore e forma: White To Off-White Solid

Peso molecolare: 261.71

Ref: 4Z-T-962

Tolfenamic Acid

CAS: 13710-19-5

Tolfenamic Acid

Purezza: ≥98%

Peso molecolare: 261.7g/mol

Ref: 54-BUP17586

2-((3-Chloro-2-Methylphenyl)Amino)Benzoic Acid

CAS: 13710-19-5

2-((3-Chloro-2-Methylphenyl)Amino)Benzoic Acid

Purezza: 98%

Peso molecolare: 261.70g/mol

Ref: 54-OR1009617

Tolfenamic-d4 Acid (Benzoic-3,4,5,6-d4)

CAS: 1246820-82-5, 13710-19-5

Purezza: 98 atom % D

Peso molecolare: 265.73

Ref: 3U-D7725

Tolfenamic acid 1000 µg/mL in Acetonitrile

Prodotto controllato

CAS: 13710-19-5

Formula: C₁₄H₁₂ClNO₂

Colore e forma: Single Solution

Peso molecolare: 261.70

Ref: 04-A17591000AL-1000

Tolfenamic Acid

Prodotto controllato

CAS: 13710-19-5

Formula: C₁₄H₁₂ClNO₂

Colore e forma: Neat

Peso molecolare: 261.70

Ref: 86-MM3395.00

Tolfenamic acid

Prodotto controllato

CAS: 13710-19-5

Formula: C₁₄H₁₂ClNO₂

Colore e forma: Neat

Peso molecolare: 261.70

Ref: 04-C17591000

Tolfenamic Acid

Prodotto controllato

CAS: 13710-19-5

Applications Non-steroidal anti-inflammatory drugs (NSAIDs). A derivative of anthranilic acid, related structurally to Mefenamic and Flufenamic acids. Anti-inflammatory, analgesic.
References Pentikaeinen, P., et al.: Eur. J. Clin. Pharmacol., 19, 359 (1981), Bundscherer, A., et al.: Oncol. Rep., 19, 547 (2008), Elwood, P., et al.: Lancet, 373, 1301 (2009),

Formula: C₁₄H₁₂ClNO₂

Colore e forma: Off-White

Peso molecolare: 261.70

Ref: TR-T535300

Tolfenamic Acid

CAS: 13710-19-5

Formula: C₁₄H₁₂ClNO₂

Purezza: 97%

Colore e forma: No data available.

Peso molecolare: 261.71

Ref: 10-F519604

Tolfenamic Acid

CAS: 13710-19-5

Tolfenamic acid is a non-steroidal anti-inflammatory drug that has been shown to inhibit the MCL-1 protein, which is involved in the regulation of programmed cell death. It has been used for the treatment of bowel disease and can be given orally or rectally. Tolfenamic acid may be effective against inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. Tolfenamic acid binds to anionic sites on the matrix of cartilage and inhibits the production of prostaglandin E2 by inhibiting cyclooxygenase activity. Tolfenamic acid has also been shown to reduce pain by inhibiting the enzyme COX-2, which is associated with inflammation. The drug also has a strong effect on human polymorphonuclear leukocytes (PMN).

Formula: C₁₄H₁₂ClNO₂

Purezza: Min. 97%

Colore e forma: Powder

Peso molecolare: 261.7 g/mol

Ref: 3D-FT28306