CAS 137636-98-7

O-(N-Acetil-α-neuraminosil)-(2→3)-O-β-D-galattopiranosil-(1→3)-O-2-(acetilamino)-2-desossi-β-D-glucopiranosil-(1→3)-O-[O-(N-acetil-α-neuraminosil)-(2→6)-O-β-D-galattopiranosil-(1→4)-2-(acetilamino)-2-desossi-β-D-glucopiranosil-(1→6)]-O-β-D-galattopiranosil-(1→4)-D-glucosio

Descrizione:

La sostanza chimica nota come O-(N-Acetil-α-neuraminosil)-(2→3)-O-β-D-galattopiranosil-(1→3)-O-2-(acetilamino)-2-desossi-β-D-glucopiranosil-(1→3)-O-[O-(N-acetil-α-neuraminosil)-(2→6)-O-β-D-galattopiranosil-(1→4)-2-(acetilamino)-2-desossi-β-D-glucopiranosil-(1→6)]-O-β-D-galattopiranosil-(1→4)-D-glucosio, con numero CAS 137636-98-7, è un composto glicosilato complesso caratterizzato da più unità di zucchero collegate tramite legami glicosidici specifici. Questa molecola presenta acido N-acetil neuraminico, che è un derivato dell'acido sialico, contribuendo alla sua importanza biologica, in particolare nei processi di riconoscimento e segnalazione cellulare. La presenza di varie unità di zucchero, inclusi derivati della galattosio e della glucosamina, indica il suo potenziale ruolo nelle strutture di glicoproteine o glicolipidi. Tali composti sono spesso coinvolti nelle interazioni cellulari, nelle risposte immunitarie e nel riconoscimento dei patogeni. La struttura intricata suggerisce che potrebbe presentare proprietà di legame specifiche, rendendola rilevante nella ricerca biochimica e nelle potenziali applicazioni terapeutiche. La sua stabilità e solubilità nei sistemi biologici dipenderebbero dall'arrangiamento dei suoi legami glicosidici e dalla presenza di gruppi funzionali.

Formula: C₆₂H₁₀₂N₄O₄₇

InChI: InChI=1S/C62H102N4O47/c1-16(74)63-31-20(78)5-61(59(96)97,111-50(31)36(85)23(81)8-68)101-15-30-38(87)43(92)44(93)56(106-30)108-48-28(13-73)104-54(33(42(48)91)65-18(3)76)100-14-29-41(90)52(45(94)57(105-29)107-47(25(83)10-70)35(84)22(80)7-67)110-55-34(66-19(4)77)49(39(88)26(11-71)102-55)109-58-46(95)53(40(89)27(12-72)103-58)113-62(60(98)99)6-21(79)32(64-17(2)75)51(112-62)37(86)24(82)9-69/h7,20-58,68-73,78-95H,5-6,8-15H2,1-4H3,(H,63,74)(H,64,75)(H,65,76)(H,66,77)(H,96,97)(H,98,99)/t20-,21-,22-,23+,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34+,35+,36+,37+,38-,39+,40-,41-,42+,43-,44+,45+,46+,47+,48+,49+,50+,51+,52-,53-,54+,55-,56-,57-,58-,61+,62-/m0/s1

InChI key: InChIKey=KRJQBUMEJQLMJO-IYWOAXAFSA-N

SMILES: O([C@@]1(C(O)=O)O[C@@]([C@@H]([C@@H](CO)O)O)([C@H](NC(C)=O)[C@@H](O)C1)[H])[C@@H]2[C@@H](O)[C@H](O[C@@H]3[C@@H](NC(C)=O)[C@H](O[C@@H]4[C@@H](O)[C@H](O[C@@H]([C@@H]([C@H](C=O)O)O)[C@@H](CO)O)O[C@H](CO[C@H]5[C@H](NC(C)=O)[C@@H](O)[C@H](O[C@@H]6O[C@H](CO[C@@]7(C(O)=O)O[C@@]([C@@H]([C@@H](CO)O)O)([C@H](NC(C)=O)[C@@H](O)C7)[H])[C@H](O)[C@H](O)[C@H]6O)[C@@H](CO)O5)[C@@H]4O)O[C@H](CO)[C@H]3O)O[C@H](CO)[C@@H]2O

Sinonimi:

• 5-(acetylamino)-2-[(6-{[5-(acetylamino)-6-[(4-{[3-(acetylamino)-4-{[4-{[5-(acetylamino)-2-carboxy-6-hydroxy-4-(1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-[1-(1,2-dihydroxyethyl)-2,3-dihydroxy-4-oxobutoxy]-3,5-dihydroxytetrahydro-2H-pyran-2-yl)methoxy]-4-hydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl]oxy}-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methoxy]-4-hydroxy-6-(1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid (non-preferred name)
• 5-Acetamido-2-[2-[3-Acetamido-2-[2-[[3-Acetamido-5-[6-[[5-Acetamido-2-Carboxy-4-Hydroxy-6-(1,2,3-Trihydroxypropyl)Oxan-2-Yl]Oxymethyl]-3,4,5-Trihydroxyoxan-2-Yl]Oxy-4-Hydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxymethyl]-3,5-Dihydroxy-6-(1,2,4,5-Tetrahydroxy-6-Oxohexan-3-Yl)Oxyoxan-4-Yl]Oxy-5-Hydroxy-6-(Hydroxymethyl)Oxan-4-Yl]Oxy-3,5-Dihydroxy-6-(Hydroxymethyl)Oxan-4-Yl]Oxy-6-Hydroxy-4-(1,2,3-Trihydroxypropyl)Oxane-2-Carboxylic Acid
• <span class="text-smallcaps">D</smallcap>-Glucose, O-(N-acetyl-α-neuraminosyl)-(2→3)-O-β-<smallcap>D</smallcap>-galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-<smallcap>D</smallcap>-glucopyranosyl-(1→3)-O-[O-(N-acetyl-α-neuraminosyl)-(2→6)-O-β-<smallcap>D</smallcap>-galactopyranosyl-(1→4)-2-(acetylamino)-2-deoxy-β-<smallcap>D</smallcap>-glucopyranosyl-(1→6)]-O-β-<smallcap>D</span>-galactopyranosyl-(1→4)-
• Disialyllacto-N-hexaose I
• Dslnh-I
• O-(N-Acetyl-α-neuraminosyl)-(2→3)-O-β-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-<smallcap>D</smallcap>-glucopyranosyl-(1→3)-O-[O-(N-acetyl-α-neuraminosyl)-(2→6)-O-β-<smallcap>D</smallcap>-galactopyranosyl-(1→4)-2-(acetylamino)-2-deoxy-β-<smallcap>D</smallcap>-glucopyranosyl-(1→6)]-O-β-<smallcap>D</smallcap>-galactopyranosyl-(1→4)-<smallcap>D</span>-glucose
• D-Glucose, O-(N-acetyl-α-neuraminosyl)-(2→3)-O-β-D-galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)-O-[O-(N-acetyl-α-neuraminosyl)-(2→6)-O-β-D-galactopyranosyl-(1→4)-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→6)]-O-β-D-galactopyranosyl-(1→4)-
• O-(N-Acetyl-α-neuraminosyl)-(2→3)-O-β-D-galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)-O-[O-(N-acetyl-α-neuraminosyl)-(2→6)-O-β-D-galactopyranosyl-(1→4)-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→6)]-O-β-D-galactopyranosyl-(1→4)-D-glucose

Disialyllacto-N-hexaose I

CAS: 137636-98-7

Disialyllacto-N-hexaose I is a complex carbohydrate that belongs to a class of saccharides called polysaccharides. Disialyllacto-N-hexaose I is synthesized through the methylation and glycosylation of sucrose. It has been modified by Click chemistry with a maleimide group to create an amide bond between the terminal alpha position on the glucose residue and the terminal alpha position on the N-acetylglucosamine residue. This modification can be used for Polysaccharide analysis, such as MALDI TOF MS. Disialyllacto-N-hexaose I has a CAS number of 137636-98-7 and has been shown to have high purity without any impurities or contaminants.

Formula: C₆₂H₁₀₂N₄O₄₇

Purezza: Min. 95%

Peso molecolare: 1,655.47 g/mol

Ref: 3D-OD64737