CAS 138402-11-6

Irbesartan

Descrizione:

Irbesartan è un antagonista del recettore dell'angiotensina II utilizzato principalmente nel trattamento dell'ipertensione e per proteggere i reni nei pazienti con diabete di tipo 2. La sua formula chimica è C18H18N4O5 e presenta una struttura a bifenile con un anello di tetrazolo, contribuendo alla sua attività farmacologica. Irbesartan agisce bloccando selettivamente il legame dell'angiotensina II al suo recettore, portando a vasodilatazione e riduzione della pressione sanguigna. Viene tipicamente somministrato per via orale e ha una emivita relativamente lunga, consentendo una somministrazione una volta al giorno. La sostanza è ben assorbita nel tratto gastrointestinale, con concentrazioni plasmatiche massime che si verificano entro poche ore dopo la somministrazione. Irbesartan è generalmente ben tollerato, con effetti collaterali comuni che includono vertigini, affaticamento e disturbi gastrointestinali. È controindicato in gravidanza e deve essere usato con cautela nei pazienti con insufficienza renale. In generale, Irbesartan è un farmaco efficace per la gestione dell'ipertensione e offre ulteriori benefici protettivi renali in popolazioni specifiche.

Formula: C₂₅H₂₈N₆O

InChI: InChI=1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30)

InChI key: InChIKey=YOSHYTLCDANDAN-UHFFFAOYSA-N

SMILES: O=C1C2(N=C(CCCC)N1CC3=CC=C(C=C3)C4=C(C=CC=C4)C=5NN=NN5)CCCC2

Sinonimi:

• 1,3-Diazaspiro[4.4]non-1-en-4-one, 2-butyl-3-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-
• 1,3-Diazaspiro[4.4]non-1-en-4-one, 2-butyl-3-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-
• 2-Butyl-3-[2′-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,3-diaza-spiro[4.4]non-1-en-4-one
• 2-Butyl-3-[[2'-(1H-Tetrazol-5-Yl)[1,1'-Biphenyl]-4-Yl]Methyl]-1,3-Diazaspiro[4.4]Non-1-En-4-One
• 2-Butyl-3-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
• 2-Butyl-3-[[2′-(tetrazol-5-yl)biphenyl-4-yl]-methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
• 2-Butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
• 2-Butyl-3-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]-1,3-diazaspiro[4.4]non-1-en-4-one
• 2-butyl-3-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
• 3-Butyl-2-[[4-[2-(2H-Tetrazol-5-Yl)Phenyl]Phenyl]Methyl]-2,4-Diazaspiro[4.4]Non-3-En-1-One
• Aprovel
• Avapro
• Bms-186295
• Irbesartan (GMP)
• Irbest
• Irbetan
• Kansartan
• Karvea
• Sabervel
• Sr-47436

Irbesartan

CAS: 138402-11-6

Formula: C₂₅H₂₈N₆O

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 428.54

Ref: 3B-I0859

Irbesartan

CAS: 138402-11-6

Colore e forma: Neat

Ref: 61-FOR0862.00

Irbesartan

CAS: 138402-11-6

Irbesartan

Formula: C₂₅H₂₈N₆O

Purezza: 99.7%

Colore e forma: Off White Solid

Peso molecolare: 428.23246

Ref: 47-1093

IRBESARTAN CRS

CAS: 138402-11-6

IRBESARTAN CRS

Formula: C₂₅H₂₈N₆O

Peso molecolare: 428.5294

Ref: 41-Y0001166

Irbesartan

CAS: 138402-11-6

Cardiovascular drugs, nesoi

Formula: C₂₅H₂₈N₆O

Colore e forma: White Off-White Crystalline Powder

Peso molecolare: 428.23246

Ref: 45-1347700

1,3-Diazaspiro[4.4]non-1-en-4-one, 2-butyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-

CAS: 138402-11-6

Formula: C₂₅H₂₈N₆O

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 428.5294

Ref: IN-DA0018Q6

Irbesartan

CAS: 138402-11-6

Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.

Formula: C₂₅H₂₈N₆O

Purezza: 99.79% - 99.81%

Colore e forma: White Crystalline Powder

Peso molecolare: 428.53

Ref: TM-T1615

Irbesartan

CAS: 138402-11-6

Irbesartan

Purezza: ≥98%

Peso molecolare: 428.53g/mol

Ref: 54-BUP17809

Irbesartan

CAS: 138402-11-6

Formula: C₂₅H₂₈N₆O

Colore e forma: White To Off-White Solid

Peso molecolare: 428.54

Ref: 4Z-I-021

3-((2’-(1H-Tetrazol-5-Yl)-[1,1’-Biphenyl]-4-Yl)Methyl)-2-Butyl-1,3-Diazaspiro[4.4]Non-1-En-4-One

CAS: 138402-11-6

3-((2’-(1H-Tetrazol-5-Yl)-[1,1’-Biphenyl]-4-Yl)Methyl)-2-Butyl-1,3-Diazaspiro[4.4]Non-1-En-4-One

Purezza: 98%

Peso molecolare: 428.53g/mol

Ref: 54-OR1010617

Irbesartan

Prodotto controllato

CAS: 138402-11-6

Formula: C₂₅H₂₈N₆O

Colore e forma: Neat

Peso molecolare: 428.53

Ref: 86-MM0862.00

Irbesartan

CAS: 138402-11-6

Formula: C₂₅H₂₈N₆O

Colore e forma: Neat

Peso molecolare: 428.53

Ref: 04-C14373000

Irbesartan

CAS: 138402-11-6

Formula: C₂₅H₂₈N₆O

Purezza: 98.0 - 102.0 % (dry basis)

Colore e forma: White to off-white powder

Peso molecolare: 428.53

Ref: 7W-GP0710

Irbesartan

Prodotto controllato

CAS: 138402-11-6

Applications An angiotensin II type 1 (AII1)-receptor antagonist.
References Gillis, J.C. and Markham, A.: Drugs, 54, 885 (1997), Chando, T.J., et al.: Drug. Metabol. Dispos., 26, 408 (1998), Massie, B., et al.: New Eng. J. Med., 359, 2456 (2008), Ren, X., et al.: Pharmacol., 83, 80 (2009),

Formula: C₂₅H₂₈N₆O

Colore e forma: Neat

Peso molecolare: 428.53

Ref: TR-I751000

2-Butyl-3-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]1,3-diaza-spiro[4.4]non-1-en-4-one

CAS: 138402-11-6

Purezza: 97.0%

Colore e forma: Solid, White - Almost white powder

Peso molecolare: 428.5400085449219

Ref: 10-F036499

Irbesartan

CAS: 138402-11-6

Angiotensin II receptor antagonis

Formula: C₂₅H₂₈N₆O

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 428.53 g/mol

Ref: 3D-FI24648

Irbesartan - Bio-X ™

CAS: 138402-11-6

Irbesartan is an angiotensin II receptor antagonist that is used to treat hypertension and congestive heart failure. It is also used to delay the progression of diabetic nephropathy. This drug works to works to relax smooth muscles and lower blood pressure.

Formula: C₂₅H₂₈N₆O

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 428.53 g/mol

Ref: 3D-BI164582