CAS 138605-00-2

β-Alanina, N,N-dimetil-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetilossi)-3-eteni-dodecahidro-10,10b-diidrossi-3,4a,7,7,10a-pentametil-1-osso-1H-nafto[2,1-b]pirano-6-il estere, cloridrato (1:1)

Descrizione:

La sostanza chimica nota come β-Alanina, N,N-dimetil-, con la stereochimica specificata e il numero CAS 138605-00-2, è un composto organico complesso caratterizzato dalla sua struttura intricata, che include più centri chirali e gruppi funzionali come esteri e idrossili. Questo composto è un derivato della β-alanina, un amminoacido che gioca un ruolo in vari processi biologici. La presenza del gruppo dimetile suggerisce una maggiore lipofilia, che può influenzare la sua solubilità e attività biologica. Il gruppo funzionale estere indica una reattività potenziale, in particolare nelle reazioni di idrolisi, che potrebbero influenzare la sua stabilità e biodisponibilità. Inoltre, la forma cloridrato implica che il composto sia un sale, probabilmente aumentando la sua solubilità in ambienti acquosi. In generale, le caratteristiche strutturali uniche di questo composto possono conferire proprietà farmacologiche specifiche, rendendolo di interesse nella chimica medicinale e nella biochimica. Tuttavia, sarebbero necessari studi dettagliati per chiarire completamente la sua attività biologica e le potenziali applicazioni.

Formula: C₂₇H₄₃NO₈·ClH

InChI: InChI=1S/C27H43NO8.ClH/c1-10-24(5)15-18(31)27(33)25(6)17(30)11-13-23(3,4)21(25)20(35-19(32)12-14-28(8)9)22(34-16(2)29)26(27,7)36-24;/h10,17,20-22,30,33H,1,11-15H2,2-9H3;1H/t17-,20-,21-,22-,24-,25-,26+,27-;/m0./s1

InChI key: InChIKey=VIRRLEDAYYYTOD-YHEOSNBFSA-N

SMILES: O[C@@]12[C@]3(C)[C@@]([C@H](OC(CCN(C)C)=O)[C@H](OC(C)=O)[C@@]1(C)O[C@](C=C)(C)CC2=O)(C(C)(C)CC[C@@H]3O)[H].Cl

Sinonimi:

• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate
• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyl-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-6-yl 4-methylpentanoate hydrochloride (1:1)
• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyl-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-6-yl N,N-dimethyl-beta-alaninate hydrochloride (1:1)
• (3R-(3-Alpha,4A-Beta,5-Beta,6-Beta,6A-Alpha,10-Alpha,10A-Beta,10B-Alpha))-Id
• 1H-Naphtho[2,1-b]pyran, β-alanine deriv.
• 6-(3-Dimethylaminopropionyl)forskolin hydrochloride
• Adehl
• Adehl (TN)
• Beta-Alanine,N,N-Dimethyl-,5-(Acetyloxy)-3-Ethenyldodecahydro-10,10B-Dihydrox
• Colforsin dapropate hydrochloride
• Colforsindapropatehydrochloride
• N,N-Dimethyl-(3R,4aR,5S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-
• Nkh 477
• Y-3,4A,7,7,10A-Pentamethyl-1-Oxo-1H-Naphtho(2,1-B)Pyran-6-Ylester,Hydrochlor
• β-Alanine, N,N-dimethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester, hydrochloride
• β-Alanine, N,N-dimethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester, hydrochloride (1:1)

NKH477

CAS: 138605-00-2

Formula: C₂₇H₄₄ClNO₈

Purezza: 98%

Peso molecolare: 546.0932

Ref: IN-DA01E1RR

NKH477

CAS: 138605-00-2

NKH477

Purezza: ≥98%

Peso molecolare: 546.09g/mol

Ref: 54-BUP21855

NKH477

CAS: 138605-00-2

NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity.

Formula: C₂₇H₄₄ClNO₈

Purezza: 98% - 98%

Colore e forma: Solid

Peso molecolare: 546.09

Ref: TM-T16332

NKH 477

Prodotto controllato

CAS: 138605-00-2

Formula: C₂₇H₄₃NO₈·ClH

Colore e forma: Neat

Peso molecolare: 546.093

Ref: TR-N605000

NKH 477

CAS: 138605-00-2

NKH 477 is a drug that has been shown to increase the amount of calcium in the cytosol of cells. It has been found to be effective at low doses, which may be due to its ability to activate phospholipase C and stimulate the release of calcium from intracellular stores. NKH477 is an analogue of glucagon-like peptide 1 (GLP-1) and has been shown to have similar effects on cardiac muscle, but with less effect on pancreatic beta cells.
The effect of NKH 477 on cardiac muscle was studied in vitro using papillary muscle strips from guinea pig hearts. The drug was shown to cause relaxation of the muscles by stimulating ryanodine receptors, which are responsible for releasing calcium from intracellular stores. This drug may also have potential as a treatment for type 2 diabetes mellitus by activating GLP-1 receptors in the pancreas.

Formula: C₂₇H₄₄ClNO₈

Purezza: Min. 95%

Peso molecolare: 546.09 g/mol

Ref: 3D-BN178886