CAS 1391053-27-2

tert-Butyl 5-{4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2,3-dihydro-1H-indole-1-carboxylate

CAS: 1391053-27-2

tert-Butyl 5-{4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2,3-dihydro-1H-indole-1-carboxylate

Purezza: ≥95%

Peso molecolare: 365.43g/mol

Ref: 54-OR310815

5-(1-tert-Butyloxycarbonyl-2,3-dihydro-1H-indol-5-yl)-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Prodotto controllato

CAS: 1391053-27-2

Applications Intermediate in the synthesis of GSK PERK Inhibitor (G797800).

Formula: C₂₀H₂₃N₅O₂

Colore e forma: Neat

Peso molecolare: 365.43

Ref: TR-B693495

tert-Butyl 5-{4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2,3-dihydro-1H-indole-1-carboxylate

CAS: 1391053-27-2

tert-Butyl 5-{4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2,3-dihydro-1H-indole-1carboxylate (ABPC) is an agonist of the ion channel TRPV4. This compound has been shown to activate TRPV4 with a high affinity and selectivity. ABPC is a potent inhibitor of cell proliferation, which may be due to its ability to inhibit protein synthesis and DNA synthesis. ABPC has also been shown to inhibit the production of cytokines such as IL1β, IL6, and TNFα in lipopolysaccharide (LPS)-stimulated murine macrophages.

Formula: C₂₀H₂₃N₅O₂

Purezza: Min. 95%

Peso molecolare: 365.4 g/mol

Ref: 3D-RFC05327