CAS 139290-65-6

(R)-(+)-ALFA-(2,3-DIMETOSSIFENIL)-1-[2-(4-FLUOROFENIL)ETIL]-4-PIPERIDINA METANOLO

Descrizione:

(R)-(+)-ALFA-(2,3-DIMETOSSIFENIL)-1-[2-(4-FLUOROFENIL)ETIL]-4-PIPERIDINA METANOLO, con numero CAS 139290-65-6, è un composto chimico caratterizzato dalla sua complessa struttura molecolare, che include un anello di piperidina e molteplici sostituenti aromatici. Questo composto è tipicamente classificato come un derivato della piperidina e può mostrare proprietà associate all'attività del sistema nervoso centrale, data la presenza della moiety di piperidina. La presenza dell'atomo di fluoro nel gruppo fenile può influenzare le sue proprietà farmacologiche, potenzialmente migliorando la lipofilia e alterando l'affinità di legame ai recettori. Il gruppo metanolo suggerisce il potenziale per legami idrogeno, il che può influenzare la solubilità e la reattività. Inoltre, la stereochimica indicata dalla configurazione (R) implica disposizioni spaziali specifiche che possono avere un impatto significativo sull'attività biologica e sulle interazioni con obiettivi biologici. In generale, le caratteristiche strutturali uniche di questo composto suggeriscono potenziali applicazioni in chimica medicinale, in particolare nello sviluppo di agenti terapeutici. Tuttavia, sarebbero necessari studi dettagliati per chiarire completamente le sue proprietà e potenziali usi.

Formula: C₂₂H₂₈FNO₃

InChI: InChI=1/C22H28FNO3/c1-26-20-5-3-4-19(22(20)27-2)21(25)17-11-14-24(15-12-17)13-10-16-6-8-18(23)9-7-16/h3-9,17,21,25H,10-15H2,1-2H3

InChI key: InChIKey=HXTGXYRHXAGCFP-OAQYLSRUSA-N

SMILES: [C@H](O)(C1=C(OC)C(OC)=CC=C1)C2CCN(CCC3=CC=C(F)C=C3)CC2

Sinonimi:

• (+)-Mdl 100907
• (+)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
• (2,3-Dimethoxyphenyl){1-[2-(4-Fluorophenyl)Ethyl]Piperidin-4-Yl}Methanol
• (R)-(2,3-Dimethoxyphenyl)-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]methanol
• (aR)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
• 4-Piperidinemethanol, 1-[2-(4-Fluorophenyl)Ethyl]-Alpha-(2,3-Dimethoxyphenyl)-, (Alphar)
• 4-Piperidinemethanol, α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-, (R)-
• 4-Piperidinemethanol, α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-, (αR)-
• M 100907
• Mdl100907
• R-Mdl 100907
• Volinanserin
• (R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL
• MDL-100907(Volinanserin)
• MDL100907 tartrate salt
• Volinanserin Hydrochloride Salt
• (aR)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Hydrochloride
• (R)-(+)-(-(2,3-Dimethoxyphenyl)-1-[2-(4-fluoro-phenyl)ethyl]-4-piperidine methanol
• MDL100907-L-tartrate
• (R)-(2,3-dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol
• (+)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Hydrochloride
• 4-Piperidinemethanol, 1-[2-(4-fluorophenyl)ethyl]-(-(2,3-dimethoxyphenyl)-, ((R), (R,R)-tartrate
• 4-Piperidinemethanol, 1-[2-(4-fluorophenyl)ethyl]-(-(2,3-dimethoxyphenyl)-, ((R)
• (+)-α-(2,3-DiMethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidineMethanol Hydrochloride
• (R)-(+)-a-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-pipidinemethanol
• (R)-(+)-(-(2,3-Dimethoxyphenyl)-1-[2-(4-fluoro-phenyl)ethyl]-4-piperidine methanol (R,R)-tartrate

4-Piperidinemethanol, α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-, (αR)-

CAS: 139290-65-6

Formula: C₂₂H₂₈FNO₃

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 373.4610

Ref: IN-DA001AP3

Volinanserin

CAS: 139290-65-6

Volinanserin

Purezza: ≥98%

Peso molecolare: 373.46g/mol

Ref: 54-BUP13230

Volinanserin

CAS: 139290-65-6

Volinanserin (MDL100907) is a potent 5-HT2 receptor antagonist with a Ki of 0.36 nM, 300x selective over 5-HT1c, alpha-1, and sigma receptors.

Formula: C₂₂H₂₈FNO₃

Purezza: 98.94% - 99.95%

Colore e forma: Solid

Peso molecolare: 373.46

Ref: TM-T5389

Volinanserin HCl

CAS: 139290-65-6

Formula: C₂₂H₂₈FNO₃·HCl

Peso molecolare: 373.47 36.46

Ref: 4Z-V-100001

(R)-(2,3-Dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol

CAS: 139290-65-6

Purezza: 95.0%

Peso molecolare: 373.4679870605469

Ref: 10-F436152

Volinanserin Hydrochloride Salt

CAS: 139290-65-6

Applications A serotonin 5-HT2A receptor antagonist. Used as potential controls in various biological studies.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wong, D.F., et al.: Science, 226, 1393 (1984), Blin, J., et al.: Eur. J. Pharmacol., 147, 73 (1988), Kehne, J.H., et al.: J. Pharmacol. Exp. Ther., 277, 968 (1996),

Formula: C₂₂H₂₈FNO₃

Colore e forma: Neat

Peso molecolare: 373.46

Ref: TR-V755000

MDL 100907

CAS: 139290-65-6

Selective antagonist of the serotonin receptors 5-HT2A with subnanomolar affinity. The compound has clozapine-like anti-psychotic properties and more favourable CNS safety profile than traditional anti-psychotics. MDL 100907 has been used in studies on antisocial behaviour in mice and shown that the blockage of 5-HT2A receptors leads to decreased post-traumatic aggression and bradycardia.

Formula: C₂₂H₂₈FNO₃

Purezza: Min. 95%

Colore e forma: White Solid

Peso molecolare: 373.46 g/mol

Ref: 3D-FV28720