CAS 139481-72-4: Trityl Candesartan

Descrizione: Trityl Candesartan, con il numero CAS 139481-72-4, è un composto chimico che appartiene alla classe degli antagonisti del recettore dell'angiotensina II, progettato specificamente per il trattamento dell'ipertensione e dell'insufficienza cardiaca. È un pro-farmaco del Candesartan, il che significa che viene convertito nella sua forma attiva nel corpo. La struttura di Trityl Candesartan presenta un gruppo tritilo, che migliora la sua lipofilia e biodisponibilità. Questo composto mostra alta affinità per il recettore dell'angiotensina II, portando a vasodilatazione e a una successiva riduzione della pressione sanguigna. Il suo profilo farmacocinetico include una buona assorbimento e una vita media relativamente lunga, consentendo una somministrazione una volta al giorno. Inoltre, Trityl Candesartan è caratterizzato dalla sua stabilità in condizioni fisiologiche, rendendolo adatto per applicazioni terapeutiche. Come per molti farmaci, è essenziale considerare i potenziali effetti collaterali e controindicazioni, che possono includere vertigini, ipotensione e compromissione renale. In generale, Trityl Candesartan rappresenta un significativo progresso nella terapia antipertensiva.

Formula: C₄₃H₃₄N₆O₃

InChI: InChI=1S/C43H34N6O3/c1-2-52-42-44-38-24-14-23-37(41(50)51)39(38)48(42)29-30-25-27-31(28-26-30)35-21-12-13-22-36(35)40-45-46-47-49(40)43(32-15-6-3-7-16-32,33-17-8-4-9-18-33)34-19-10-5-11-20-34/h3-28H,2,29H2,1H3,(H,50,51)

InChI key: InChIKey=VBMKOTRJWPIKMG-UHFFFAOYSA-N

SMILES: O=C(O)C1=CC=CC=2N=C(OCC)N(C21)CC=3C=CC(=CC3)C=4C=CC=CC4C5=NN=NN5C(C=6C=CC=CC6)(C=7C=CC=CC7)C=8C=CC=CC8

Sinonimi:

• 1H-benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-
• 2-Ethoxy-1-((2′-(1-trityl-1H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylic acid
• 2-Ethoxy-1-[(2′-(1-trityl-1H-tetrazol-5-yl)-1,1′-biphenyl-4-yl)methyl]-7-benzimidazolecarboxylic acid
• 2-Ethoxy-1-[[2′-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1′-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid
• 2-Ethoxy-1-{[2'-(1-trityl-1H-tetrazol-5-yl)-4-biphenylyl]methyl}-1H-benzimidazole-7-carboxylic acid
• 2-Ethoxy-1-{[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid
• 2-ethoxy-1-[[(2'-(1-triphenylmethyl-1h-tetrazol-5-yl)biphenyl-4-yl)methyl]benzimidazole-7-carboxylic acid
• DISCONTINUED
• TritylCandesartan[CandesartabCilexetilIntermediates]
• Candesartan Cilexetil Impurity 9
• 2-Ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-c
• 2-ETHOXY-1-[[(2-(1-TRIPHENYLMETHYL-1H-TETRAZOL-5-YL)BIPHENYL)METHYL] BENZIMIDAZOLE-7-CARBOXYLIC ACID
• 2-ethoxy-3-[[4-[2-[1-(triphenylmethyl)-5-tetrazolyl]phenyl]phenyl]methyl]-4-benzimidazolecarboxylic acid
• (Trityl candesartan)2-Ethoxy-1-[[2-(2-Triphenyl Methyl)-2H-Tetrazole-5-YL](1,1-Biphenyl)-4-YL]Methyl]Benzimidazole-2-Carboxylic Acid
• Triphenyl Candesartan
• Candesartan N1-Trityl IMpurity
• (1H)-Benzimidazole-7-carboxylicacid
• 2-Ethoxy-1-[[(2’-(1-triphenylmethyl-1H-tetrazol-5-yl)biphenyl-4-yl-)methyl]benzimidazole-7-carboxylicacid
• Trityl candesartan/2-Ethoxy-1-[[(2'-(1-triphenylmethyl-1H-tetrazol-5-yl)biphenyl-4-yl)methyl]benzimidazole-7-carboxylic acid
• Candesartan Impurity 8
• TRITYL CANDESARTAN
• TRITYL CANDESARTAN ( FOR CANDESARTAN CILEXETIL )
• Trityl candesartan USP/EP/BP
• Yl][1,1?-Biphenyl]-4-Yl]Methyl]-1H-Benzimidazole-7- Carboxylic Acid [N-Trityl Candesartan]
• N-Trityl Candesartan
• 2-Ethoxy-1-[[2?-[2-(Triphenylmethyl)-2H-Tetrazol-5-
• 2-ethoxy-1-[[(2-(1-triphenylmethyl-1Htetrazol-5-yl)biphenyl-4-yl-)
• CANDESARTAN INTERMEDIATE A
• Intermediate 5
• 2-Ethoxy-1-[[2-(2-Triphenylmethyl)-2H-Tetrazole-5-Yl](1,1-Biphenyl)-4-Yl]-Methyl]Benzimidazole-7-Carboylicacid
• Candesartan Cilexetil
• N-trimethylcandesartan
• Candesartan Cilexetil Impurity 14
• Trityl Candesartan (C9)
• 2-Ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-
• TritylCandesartan,CandesartanCilexetil
• 1H-benzimidazole-7-carboxylic acid, 1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-2-ethoxy

Trityl candesartan

CAS: 139481-72-4

• Formula: C₄₃H₃₄N₆O₃
• Purezza: 97%
• Colore e forma: Solid
• Peso molecolare: 682.7685

N-Trityl Candesartan

CAS: 139481-72-4

• Formula: C₄₃H₃₄N₆O₃
• Colore e forma: White To Off-White Solid
• Peso molecolare: 682.79

Trityl candesartan

CAS: 139481-72-4

Trityl candesartan is a crucial intermediate used in the synthesis of Candesartan and Candesartan cilexetil, …

• Formula: C₄₃H₃₄N₆O₃
• Purezza: 98.97%
• Colore e forma: Solid
• Peso molecolare: 682.77

N-Trityl Candesartan

CAS: 139481-72-4

• Formula: C₄₃H₃₄N₆O₃
• Peso molecolare: 682.77

N-Trityl candesartan

CAS: 139481-72-4

N-Trityl candesartan is a benzimidazole derivative. It is a prodrug that is activated by esterases …

• Formula: C₄₃H₃₄N₆O₃
• Purezza: Min. 95%
• Peso molecolare: 682.77 g/mol