CAS 1400-61-9

Nistatina

Descrizione:

Nistatina è un farmaco antifungino utilizzato principalmente per trattare le infezioni fungine, in particolare quelle causate da specie di Candida. È un antibiotico macrolide polieno derivato dal batterio Streptomyces noursei. Nistatina presenta un caratteristico colore giallastro ed è solubile in dimetilsolfossido (DMSO) e leggermente solubile in acqua, il che limita il suo uso sistemico a causa della potenziale tossicità. Il meccanismo d'azione implica il legame all'ergosterolo, un componente chiave delle membrane cellulari fungine, portando alla formazione di pori che interrompono l'integrità della membrana e causano la morte cellulare. Nistatina viene tipicamente somministrato topicamente o per via orale, a seconda del tipo e della posizione dell'infezione, ed è comunemente usato nel trattamento della candidosi orale e delle infezioni cutanee. Sebbene generalmente ben tollerato, può causare irritazione locale o reazioni allergiche in alcuni individui. Il suo uso è controindicato in pazienti con ipersensibilità nota al farmaco o ai suoi componenti. In generale, Nistatina rimane un agente importante nella gestione delle infezioni fungine superficiali.

Formula: Unspecified

InChI: InChI=1/C18H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h3-10H,2,11-17H2,1H3,(H,19,20)

SMILES: CCC=CC=CC=CC=CCCCCCCCC(=O)O

Sinonimi:

• (21E,23E,25E,27E,31E,33E)-20-[(3-amino-3,6-dideoxy-D-mannopyranosyl)oxy]-4,6,8,11,12,16,18,36-octahydroxy-35,37,38-trimethyl-2,14-dioxooxacyclooctatriaconta-21,23,25,27,31,33-hexaene-17-carboxylic acid
• 33-[(3-Amino-3,6-Dideoxyhexopyranosyl)Oxy]-3,4,7,9,11,17,37-Heptahydroxy-15,16,18-Trimethyl-13-Oxo-14,39-Dioxabicyclo[33.3.1]Nonatriaconta-19,21,25,27,29,31-Hexaene-36-Carboxylic Acid
• <span class="text-smallcaps">L</span>-Nystatin
• Biofanal
• Candio-Hermal
• Ceratocide
• Diastatin
• Flagystatin
• Fungicidin
• L-Nystatin
• Moronal (antibiotic)
• Myconystatin
• Mycostatin
• Mycostatin Pastilles
• Mykostatyna
• N-[1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]-4-phenylbutan-2-aminium chloride
• Nilstat
• Nistatin
• Nistatina
• Nyotran
• Nysfungin
• Nystacid
• Nystan
• Nystatin
• Nystatin Suspension Cell Culture Tested
• Nystatin, Streptomyces noursei, Sterile, TC Grade
• Nystatine
• Nystavescent
• Nystex
• Nystop
• O-V Statin
• Octadeca-9,11,13,15-Tetraenoic Acid

Nystatin

CAS: 1400-61-9

Nystatin, 1400-61-9, is a macrolide complex with antifungal and antibiotic properties which exhibits activity against several species of yeast. Learn more.

Formula: C₄₇H₇₅NO₁₇

Colore e forma: White to pale cream, Powder

Peso molecolare: 926.11

Ref: 02-J62486

NYSTATIN CRS

CAS: 1400-61-9

NYSTATIN CRS

Formula: C₁₈H₂₈O₂

Peso molecolare: 276.4137

Ref: 41-N1400000

NYSTATIN RS

CAS: 1400-61-9

NYSTATIN RS

Formula: C₁₈H₂₈O₂

Peso molecolare: 276.4137

Ref: 41-ICRS0369

THIRD INTERNATIONAL STANDARD FOR NYSTATIN

CAS: 1400-61-9

THIRD INTERNATIONAL STANDARD FOR NYSTATIN

Formula: C₁₈H₂₈O₂

Peso molecolare: 276.4137

Ref: 41-ISA_29384

Nystatin

CAS: 1400-61-9

Aminoglycoside antibiotics

Formula: C₄₇H₇₅NO₁₇

Colore e forma: Yellow Light Tan Powder

Peso molecolare: 925.5035

Ref: 45-1477003

Nystatin

CAS: 1400-61-9

Formula: C₄₇H₇₅NO₁₇

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 926.0949

Ref: IN-DA001BY5

Nystatin

CAS: 1400-61-9

Formula: C₄₇H₇₅NO₁₇

Colore e forma: Yellow Solid

Peso molecolare: 926.11

Ref: 4Z-N-082001

Nystatin hydrate

CAS: 1400-61-9

Formula: C₄₇H₇₅NO₁₇·xH₂O

Purezza: ≥ 4500U/mg (dried basis)

Colore e forma: Yellow to brown-yellow powder

Peso molecolare: 926.09 (anhydrous)

Ref: 7W-GA3995

Nystatin

CAS: 1400-61-9

Nystatin

Purezza: ≥60%

Peso molecolare: 926.1g/mol

Ref: 54-BUP18530

Nystatin hydrate, 4400 U/mg, USP grade

CAS: 1400-61-9

Formula: C₄₇H₇₅NO₁₇·xH₂O

Purezza: ≤ 4.0%

Colore e forma: Yellow to dark yellow or tan powder

Peso molecolare: 926.09 (anhydrous)

Ref: 7W-GP7660

Nystatin dihydrate

CAS: 1400-61-9

Nystatin dihydrate

Formula: C₄₇H₇₅NO₁₇·2H₂O

Purezza: By hplc: 91 area-% (Typical Value in Batch COA)

Colore e forma: yellow powder

Peso molecolare: 962.12546g/mol

Ref: 54-BIN0138

Nystatin

Prodotto controllato

CAS: 1400-61-9

Formula: C₄₇H₇₅NO₁₇

Colore e forma: Neat

Peso molecolare: 926.09

Ref: 04-C15661000

Nystatin

CAS: 1400-61-9

Nystatin (Fungicidin) is a topical and oral antifungal agent with activity against many species of yeast and candida albicans, which is used largely to treat

Formula: C₄₇H₇₅NO₁₇

Purezza: 69.55% - 99.53%

Colore e forma: Yellow Suspension

Peso molecolare: 926.1

Ref: TM-T1678

Nystatin

CAS: 1400-61-9

Applications Polyene antifungal antibiotic complex containing 3 biologically active components, A1, A2, A3. Increases the permeability of the cell membrane of sensitive fungi by binding to sterols. Cell culture tested. Growth promotant.Nystatin A1 is shown.
References Brautaset, T., et al.: Chem. Biol., 7, 395 (2000), Brautaset, T., et al.: J. Biol. Chem., 278, 14913 (2003), Bruheim, P., et al.: Antimicrob. Agents Chemother., 48, 4120 (2004), Scott, L., et al.: Drugs, 67, 269 (2007),

Formula: C₄₇H₇₅NO₁₇

Colore e forma: Neat

Peso molecolare: 926.09

Ref: TR-N926000

Nystatin

CAS: 1400-61-9

Nystatin is an antifungal compound, which is produced by the bacterium *Streptomyces noursei*. It functions by binding to ergosterol, a crucial component of fungal cell membranes, creating pores that lead to increased membrane permeability. This disruption results in the leakage of essential cellular components, ultimately causing cell death.

Formula: C₄₇H₇₅NO₁₇

Purezza: Min. 85 Area-%

Colore e forma: Powder

Peso molecolare: 926.09 g/mol

Ref: 3D-MM31116

iso-Nystatin

CAS: 1400-61-9

iso-Nystatin is an antifungal compound, which is derived from the bacterium *Streptomyces noursei*. This specific strain of actinobacteria produces polyene macrolide antifungals, and iso-Nystatin is a derivative that exhibits similar bioactivity as its parent compound, Nystatin. Its mode of action is based on binding ergosterol, a crucial component of fungal cell membranes. This binding disrupts the membrane's structural integrity, inducing pore formation, which leads to ion leakage and ultimately cell lysis and fungal cell death.

Formula: C₄₇H₇₅NO₁₇

Purezza: Min. 95%

Peso molecolare: 926.09 g/mol

Ref: 3D-FN177277

Nystatin (Mycostatin) Solution (10000U/ml) for cell culture, Endotoxin (BET) 10.0EU/ml

CAS: 1400-61-9

Formula: C₄₇H₇₅NO₁₇

Colore e forma: Pale yellow to yellow, Suspension

Peso molecolare:  926.09

Ref: SR-17565

Nystatin (Mycostatin) for cell culture, 85%, Endotoxin (BET) 0.05EU/mg

CAS: 1400-61-9

Formula: C₄₇H₇₅NO₁₇

Purezza: min. 85%

Colore e forma: Yellow to slightly brownish, Powder

Peso molecolare: 926.09

Ref: SR-16828