CAS 14003-96-4

2H-1-Benzopyran-8-carboxaldehyde, 7-hydroxy-4-methyl-2-oxo-

CAS: 14003-96-4

Formula: C₁₁H₈O₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 204.1788

Ref: IN-DA001BYN

4μ8C

CAS: 14003-96-4

4μ8C

Purezza: 99%

Peso molecolare: 204.18g/mol

Ref: 54-OR1023959

4μ8C

CAS: 14003-96-4

4μ8C

Purezza: ≥95%

Peso molecolare: 204.18g/mol

Ref: 54-BUP13207

4μ8C

CAS: 14003-96-4

Formula: C₁₁H₈O₄

Purezza: >95.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 204.18

Ref: 3B-M3735

4μ8C

CAS: 14003-96-4

4μ8C (IRE1 Inhibitor III)(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor.

Formula: C₁₁H₈O₄

Purezza: 97.48% - 98.45%

Colore e forma: Solid

Peso molecolare: 204.18

Ref: TM-T6363

7-Hydroxy-4-methyl-2-oxo-2H-chromene-8-carbaldehyde

CAS: 14003-96-4

7-Hydroxy-4-methyl-2-oxo-2H-chromene-8-carbaldehyde is an activated molecule that exhibits significant cytotoxicity to human liver cancer cells. It inhibits the mitochondrial membrane potential, leading to the release of cytochrome c and apoptosis induction. 7HMOCA has been shown to be a reactive molecule with benzimidazole derivative properties. This compound depletes cellular glutathione levels and increases intracellular reactive oxygen species (ROS) levels, which leads to DNA fragmentation, cell cycle arrest, and ultimately apoptosis induction when combined with other agents. The fluorescence properties of this molecule have enabled its detection in living cells without the need for additional reagents or labeling.

Formula: C₁₁H₈O₄

Purezza: Min. 95 Area-%

Colore e forma: White Powder

Peso molecolare: 204.18 g/mol

Ref: 3D-FH117553

7-hydroxy-4-methyl-2-oxo-2H-chromene-8-carbaldehyde

CAS: 14003-96-4

Formula: C₁₁H₈O₄

Purezza: ≥98%(HPLC)

Peso molecolare: 204.181

Ref: 10-F366810

8-Formyl-4-methylumbelliferone

Prodotto controllato

CAS: 14003-96-4

Applications 8-Formyl-4-methylumbelliferone is an inhibitor that blocks substrate access to the active site of IRE1 and selectively inactivates both Xbp1 splicing and IRE1-mediated mRNA degradation.
References Cross, B.C.S., et. al.: Proc. Natl. Acad. Sci. USA, 109, E869 (2012)

Formula: C₁₁H₈O₄

Colore e forma: Neat

Peso molecolare: 204.18

Ref: TR-F700835