CAS 1404-93-9

Vancomicina, cloridrato

Descrizione:

L'idrocloruro di vancomicina è un antibiotico glicopeptidico utilizzato principalmente per trattare infezioni batteriche gravi, in particolare quelle causate da batteri Gram-positivi, inclusi Staphylococcus aureus resistente alla meticillina (MRSA). È caratterizzato dalla sua struttura complessa, che include una serie di aminoacidi e gruppi di zucchero che contribuiscono al suo meccanismo d'azione. La vancomicina agisce inibendo la sintesi della parete cellulare nei batteri, portando infine alla lisi cellulare e alla morte. La forma idroclorurata ne migliora la solubilità in acqua, rendendola adatta per somministrazione endovenosa. Viene tipicamente somministrata in un contesto clinico a causa della sua potenza e della necessità di monitorare potenziali effetti collaterali, come la nefrotossicità e l'ototossicità. La vancomicina è anche nota per il suo spettro di attività, che è limitato a determinati tipi di batteri, ed è spesso riservata per casi in cui altri antibiotici sono inefficaci. Il suo uso è guidato da test di suscettibilità per garantire l'efficacia e combattere lo sviluppo della resistenza agli antibiotici.

Formula: C₆₆H₇₅Cl₂N₉O₂₄·xClH

InChI: InChI=1S/C66H75Cl2N9O24.ClH/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92;/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95);1H/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-;/m0./s1

InChI key: InChIKey=LCTORFDMHNKUSG-XTTLPDOESA-N

SMILES: O(C=1C2=CC3=CC1OC=4C(Cl)=CC(=CC4)[C@@H](O)[C@@H](NC([C@@H](CC(C)C)NC)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@]3(C(=O)N[C@@]5(C=6C=C(C=7C([C@@H](C(O)=O)NC(=O)[C@]([C@H](O)C=8C=C(Cl)C(O2)=CC8)(NC5=O)[H])=CC(O)=CC7O)C(O)=CC6)[H])[H])[C@H]9[C@H](O[C@H]%10C[C@](C)(N)[C@H](O)[C@H](C)O%10)[C@@H](O)[C@H](O)[C@@H](CO)O9.Cl

Sinonimi:

• (1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[(2R)-4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.23,6.214,17.18,12.129,33.010,25.034,39]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid hydrochloride (non-preferred name)
• (1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[(2R)-4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2~3,6~.2~14,17~.1~8,12~.1~29,33~.0~10,25~.0~34,39~]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid (non-preferred name)
• (3S-(3R*,6S*(S*),7S*,22S*,23R*,26R*,36S*,38aS*))-3-(2-Amino-2-oxoethyl)-44-((2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl)oxy)-10,19-dichloro-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-((4-methyl-2-(methylamino)-1-oxopentyl)amino)-2,5,24,38,39-pentaoxo-22H-8,11:18,21-dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-(1,6,9)oxadiazacyclohexadecino(4,5-m)(10,2,16)benzoxadiazacyclotetracosine-26-carboxylic acid, monohydrochloride
• 22H-8,11:18,21-Dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine, vancomycin deriv.
• 48-({3-[(4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy]-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl}oxy)-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2~3,6~.2~14,17~.1~8,12~.1~29,33~.0~10,25~.0~34,39~]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid hydrochloride (1:1) (non-preferred name)
• Laikexin
• Lyphocin
• Unii-71Wo621Tjd
• Vancocin hydrochloride
• Vancocine hydrochloride
• Vancocyn
• Vancomycin HCl
• Vancomycin monohydrochloride
• Vancor

Vancomycin hydrochloride, Molecular Biology Grade

CAS: 1404-93-9

Vancomycin hydrochloride, 1404-93-9, is a polypeptide with antibiotic properties suitable for laboratory study of bacterial infections. Learn more at Thermo Fisher Scientific.

Formula: C₆₆H₇₆Cl₃N₉O₂₄

Colore e forma: White to tan to brown, Free-flowing powder

Peso molecolare: 1485.72

Ref: 02-J62790

Vancomycin hydrochloride, 50 mg/ml in distilled water, sterile-filtered

CAS: 1404-93-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Ref: 02-J67251

Vancomycin Hydrochloride

CAS: 1404-93-9

Colore e forma: Neat

Ref: 61-FOR0239.00

SECOND INTERNATIONAL STANDARD FOR VANCOMYCIN

CAS: 1404-93-9

SECOND INTERNATIONAL STANDARD FOR VANCOMYCIN

Formula: C₆₆H₇₅Cl₂N₉O₂₄

Peso molecolare: 1449.254

Ref: 41-ISA_39036

VANCOMYCIN FOR SYSTEM SUITABILITY CRS

CAS: 1404-93-9

VANCOMYCIN FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0002080

VANCOMYCIN HYDROCHLORIDE CRS

CAS: 1404-93-9

VANCOMYCIN HYDROCHLORIDE CRS

Formula: C₆₆H₇₅Cl₂N₉O₂₄

Colore e forma: White. Powder.

Peso molecolare: 1449.254

Ref: 41-V0045000

Vancomycin B with Monodechlorovancomycin

CAS: 1404-93-9

Diagnostic or lab reagents on a backing, prepared diagnostic or lab reagents whether or not on a backing, whether or not in the form of kits, nesoi

Formula: C₆₆H₇₅Cl₂N₉O₂₄·HCl

Colore e forma: Off-White Tan Powder

Peso molecolare: 1483.40688

Ref: 45-1709018

Vancomycin B

CAS: 1404-93-9

Antibiotics nesoi

Formula: C₆₆H₇₅Cl₂N₉O₂₄·HCl

Colore e forma: White Brown Powder

Peso molecolare: 1483.40688

Ref: 45-1709029

Vancomycin, hydrochloride

CAS: 1404-93-9

Formula: C₆₆H₇₆Cl₃N₉O₂₄

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 1485.7145

Ref: IN-DA001CD1

Vancomycin hydrochloride

CAS: 1404-93-9

Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!

Formula: C₆₆H₇₆Cl₃N₉O₂₄

Purezza: 97.20% - 99.19%

Colore e forma: Off White Powder

Peso molecolare: 1485.71

Ref: TM-T0832

Vancomycin hydrochloride

CAS: 1404-93-9

Vancomycin hydrochloride

Formula: C₆₆H₇₅Cl₂N₉O₂₄·ClH

Purezza: Heavy metals: <30 ppm. (Typical Value in Batch COA)

Colore e forma: white. almost white or tan to brown free flowing powder

Peso molecolare: 1,485.71g/mol

Ref: 54-BIV0155

Vancomycin hydrochloride, low endotoxin

CAS: 1404-93-9

Formula: C₆₆H₇₅Cl₂N₉O₂₄·HCl

Purezza: ≤ 5.0%

Colore e forma: White to tan powder

Peso molecolare: 1485.73

Ref: 7W-GP4819

Vancomycin hydrochloride

CAS: 1404-93-9

Formula: C₆₆H₇₅Cl₂N₉O₂₄·HCl

Purezza: ≤ 5.0%

Colore e forma: White to tan powder

Peso molecolare: 1485.73

Ref: 7W-GA6284

Vancomycin hydrochloride BioChemica

CAS: 1404-93-9

Vancomycin hydrochloride BioChemica

Colore e forma: Solid

Peso molecolare: 1,485.71g/mol

Ref: 54-BIA1839

Vancomycin hydrochloride

Prodotto controllato

CAS: 1404-93-9

Formula: C₆₆H₇₅Cl₂N₉O₂₄·ClH

Colore e forma: Neat

Peso molecolare: 1485.71

Ref: 04-C17900500

Vancomycin Hydrochloride

Prodotto controllato

CAS: 1404-93-9

Formula: C₆₆H₇₅Cl₂N₉O₂₄·ClH

Colore e forma: Neat

Peso molecolare: 1485.71

Ref: 86-MM0239.00

Vancomycin solution

CAS: 1404-93-9

Vancomycin solution

Colore e forma: Solution

Peso molecolare: 1,485.71g/mol

Ref: 54-BIG1035

Vancomycin Hydrochloride RS

CAS: 1404-93-9

Colore e forma: White Solid Powder

Ref: 2K-7000800021

Vancomycin Hydrochloride (90%)

CAS: 1404-93-9

Stability Hygroscopic
Applications Vancomycin Hydrochloride is an antibiotic used against gram-positive bacterial strains.
References Yao, N., et al.: Biopolymers, 90, 421 (2008); Lai, H., et al.: ACS Appl. Mater. Interfaces, 7, 2046 (2015);

Formula: C₆₆H₇₅Cl₂N₉O₂₄·ClH

Purezza: 90%

Colore e forma: Neat

Peso molecolare: 1485.71

Ref: TR-V096533

Vancomycin HCl - pharma grade

CAS: 1404-93-9

Vancomycin is a tricyclic glycopeptide antibiotic that has bactericidal effects against staphylococci, streptococci, and other gram-positive bacteria. It is often used as an alternative treatment for severe staphylococcal and streptococcal infections, including endocarditis, and infections with MRSA (methicillin-resistant Staphylococcus aureus), penicillin-resistant pneumococci or in cases of allergy to penicillins and cephalosporins.

Formula: C₆₆H₇₅Cl₂N₉O₂₄·HCl

Colore e forma: Powder

Peso molecolare: 1,485.71 g/mol

Ref: 3D-AV11352