CAS 1404-93-9
:Vancomicina, cloridrato
Descrizione:
L'idrocloruro di vancomicina è un antibiotico glicopeptidico utilizzato principalmente per trattare infezioni batteriche gravi, in particolare quelle causate da batteri Gram-positivi, inclusi Staphylococcus aureus resistente alla meticillina (MRSA). È caratterizzato dalla sua struttura complessa, che include una serie di aminoacidi e gruppi di zucchero che contribuiscono al suo meccanismo d'azione. La vancomicina agisce inibendo la sintesi della parete cellulare nei batteri, portando infine alla lisi cellulare e alla morte. La forma idroclorurata ne migliora la solubilità in acqua, rendendola adatta per somministrazione endovenosa. Viene tipicamente somministrata in un contesto clinico a causa della sua potenza e della necessità di monitorare potenziali effetti collaterali, come la nefrotossicità e l'ototossicità. La vancomicina è anche nota per il suo spettro di attività, che è limitato a determinati tipi di batteri, ed è spesso riservata per casi in cui altri antibiotici sono inefficaci. Il suo uso è guidato da test di suscettibilità per garantire l'efficacia e combattere lo sviluppo della resistenza agli antibiotici.
Formula:C66H75Cl2N9O24·xClH
InChI:InChI=1S/C66H75Cl2N9O24.ClH/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92;/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95);1H/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-;/m0./s1
InChI key:InChIKey=LCTORFDMHNKUSG-XTTLPDOESA-N
SMILES:O(C=1C2=CC3=CC1OC=4C(Cl)=CC(=CC4)[C@@H](O)[C@@H](NC([C@@H](CC(C)C)NC)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@]3(C(=O)N[C@@]5(C=6C=C(C=7C([C@@H](C(O)=O)NC(=O)[C@]([C@H](O)C=8C=C(Cl)C(O2)=CC8)(NC5=O)[H])=CC(O)=CC7O)C(O)=CC6)[H])[H])[C@H]9[C@H](O[C@H]%10C[C@](C)(N)[C@H](O)[C@H](C)O%10)[C@@H](O)[C@H](O)[C@@H](CO)O9.Cl
Sinonimi:- (1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[(2R)-4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.23,6.214,17.18,12.129,33.010,25.034,39]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid hydrochloride (non-preferred name)
- (1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[(2R)-4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2~3,6~.2~14,17~.1~8,12~.1~29,33~.0~10,25~.0~34,39~]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid (non-preferred name)
- (3S-(3R*,6S*(S*),7S*,22S*,23R*,26R*,36S*,38aS*))-3-(2-Amino-2-oxoethyl)-44-((2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl)oxy)-10,19-dichloro-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-((4-methyl-2-(methylamino)-1-oxopentyl)amino)-2,5,24,38,39-pentaoxo-22H-8,11:18,21-dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-(1,6,9)oxadiazacyclohexadecino(4,5-m)(10,2,16)benzoxadiazacyclotetracosine-26-carboxylic acid, monohydrochloride
- 22H-8,11:18,21-Dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine, vancomycin deriv.
- 48-({3-[(4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy]-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl}oxy)-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2~3,6~.2~14,17~.1~8,12~.1~29,33~.0~10,25~.0~34,39~]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid hydrochloride (1:1) (non-preferred name)
- Laikexin
- Lyphocin
- Unii-71Wo621Tjd
- Vancocin hydrochloride
- Vancocine hydrochloride
- Vancocyn
- Vancomycin HCl
- Vancomycin monohydrochloride
- Vancor
- Vedi altri sinonimi
Ordinare per
Purezza (%)
0
100
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0
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50
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90
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95
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100
Vancomycin hydrochloride, Molecular Biology Grade
CAS:Vancomycin hydrochloride, 1404-93-9, is a polypeptide with antibiotic properties suitable for laboratory study of bacterial infections. Learn more at Thermo Fisher Scientific.
Formula:C66H76Cl3N9O24Colore e forma:White to tan to brown, Free-flowing powderPeso molecolare:1485.72Vancomycin hydrochloride, 50 mg/ml in distilled water, sterile-filtered
CAS:This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci
SECOND INTERNATIONAL STANDARD FOR VANCOMYCIN
CAS:SECOND INTERNATIONAL STANDARD FOR VANCOMYCINFormula:C66H75Cl2N9O24Peso molecolare:1449.254VANCOMYCIN HYDROCHLORIDE CRS
CAS:VANCOMYCIN HYDROCHLORIDE CRSFormula:C66H75Cl2N9O24Colore e forma:White. Powder.Peso molecolare:1449.254Vancomycin B
CAS:Antibiotics nesoiFormula:C66H75Cl2N9O24·HClColore e forma:White Brown PowderPeso molecolare:1483.40688Vancomycin B with Monodechlorovancomycin
CAS:Diagnostic or lab reagents on a backing, prepared diagnostic or lab reagents whether or not on a backing, whether or not in the form of kits, nesoiFormula:C66H75Cl2N9O24·HClColore e forma:Off-White Tan PowderPeso molecolare:1483.40688Vancomycin, hydrochloride
CAS:Formula:C66H76Cl3N9O24Purezza:95%Colore e forma:SolidPeso molecolare:1485.7145Vancomycin hydrochloride
CAS:Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!Formula:C66H76Cl3N9O24Purezza:97.20% - 99.19%Colore e forma:Off White PowderPeso molecolare:1485.71Vancomycin hydrochloride
CAS:Vancomycin hydrochlorideFormula:C66H75Cl2N9O24·ClHPurezza:Heavy metals: <30 ppm. (Typical Value in Batch COA)Colore e forma: white. almost white or tan to brown free flowing powderPeso molecolare:1,485.71g/molVancomycin hydrochloride, low endotoxin
CAS:Formula:C66H75Cl2N9O24·HClPurezza:≤ 5.0%Colore e forma:White to tan powderPeso molecolare:1485.73Vancomycin hydrochloride BioChemica
CAS:Vancomycin hydrochloride BioChemicaColore e forma:SolidPeso molecolare:1,485.71g/molVancomycin hydrochloride
CAS:Formula:C66H75Cl2N9O24·HClPurezza:≤ 5.0%Colore e forma:White to tan powderPeso molecolare:1485.73Vancomycin hydrochloride (Standard)
CAS:Vancomycin hydrochloride (Standard) is the standard substance of Vancomycin hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Vancomycin hydrochloride (Vancomycin HCl) is a glycopeptide antibiotic that targets Peptidoglycan in bacterial cell wall synthesis. Vancomycin hydrochloride is mainly used for the treatment of severe Gram-positive bacterial infections.Formula:C66H76Cl3N9O24Colore e forma:Off White PowderPeso molecolare:1485.71Vancomycin hydrochloride
CAS:Prodotto controllatoFormula:C66H75Cl2N9O24·ClHColore e forma:NeatPeso molecolare:1485.71Vancomycin Hydrochloride
CAS:Prodotto controllatoFormula:C66H75Cl2N9O24·ClHColore e forma:NeatPeso molecolare:1485.71Vancomycin Hydrochloride (90%)
CAS:Stability Hygroscopic
Applications Vancomycin Hydrochloride is an antibiotic used against gram-positive bacterial strains.
References Yao, N., et al.: Biopolymers, 90, 421 (2008); Lai, H., et al.: ACS Appl. Mater. Interfaces, 7, 2046 (2015);Formula:C66H75Cl2N9O24·ClHPurezza:90%Colore e forma:NeatPeso molecolare:1485.71
