CAS 1405-89-6

Bacitracina zinco

Descrizione:

Bacitracina zinco è un composto antibiotico che è una miscela complessa di polipeptidi ciclici prodotti dal batterio Bacillus subtilis. È utilizzato principalmente per le sue proprietà antibatteriche, in particolare contro i batteri Gram-positivi. La forma di sale di zinco ne migliora la stabilità e la solubilità, rendendolo adatto per varie applicazioni, comprese le pomate topiche e la medicina veterinaria. Bacitracina zinco agisce inibendo la sintesi della parete cellulare batterica, il che porta infine alla lisi cellulare e alla morte. Viene spesso utilizzato in combinazione con altri antibiotici per ampliare il suo spettro di attività. Il composto è generalmente considerato sicuro per uso topico, ma può causare reazioni allergiche in alcuni individui. In termini di proprietà fisiche, Bacitracina zinco è tipicamente una polvere bianca o bianco sporco che è solubile in acqua e ha un sapore leggermente amaro. Il suo uso è regolamentato ed è importante seguire le linee guida per prevenire lo sviluppo di resistenza agli antibiotici.

Formula: Unspecified

InChI: InChI=1/C66H103N17O16S.Zn/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90;/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88);/q;+2/p-2/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48?,52?,53-,54-;/m0./s1

SMILES: CCC(C)C(C1=NC(CS1)C(=NC(CC(C)C)C(=NC(CCC(=O)O)C(=NC(C(C)CC)C(=NC1CCCCN=C(C(CC(=N)O)N=C(C(CC(=O)O)N=C(C(Cc2cnc[nH]2)N=C(C(Cc2ccccc2)N=C(C(C(C)CC)N=C(C(CCCN)N=C1O)O)O)O)O)O)O)O)O)O)O)N.[Zn]

Sinonimi:

• Albac
• Bacifarmin
• Bacifarmin-zinc
• Baciferm
• Baciferm PB
• Bacitracin Zinc
• Bacitracin zinc salt
• L-isoleucinamide, N-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucyl-D-alpha-glutamyl-N-[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-15-(1-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-12-(phenylmethyl)-1,4,7,10,13,16,19-heptaazacyclopentacos-21-yl]-, zinc salt (1:1)
• Noptracin
• St 56
• zinc N-{[2-(1-amino-2-methylbutyl)-4,5-dihydro-1,3-thiazol-4-yl]carbonyl}-L-leucyl-5-oxidanidyl-5-oxidanylidene-D-norvalyl-N-{(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-6-(carboxylatomethyl)-9-(1H-imidazol-5-ylmethyl)-15-[(1S)-1-methylpropyl]-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl}-L-isoleucinamide

BACITRACIN FOR SYSTEM SUITABILITY CRS

CAS: 1405-89-6

BACITRACIN FOR SYSTEM SUITABILITY CRS

Formula: C₆₆H₁₀₃N₁₇O₁₆SZn

Colore e forma: White. Yellow. Powder.

Peso molecolare: 1488.101

Ref: 41-Y0001867

SECOND INTERNATIONAL STANDARD FOR BACITRACIN

CAS: 1405-89-6

SECOND INTERNATIONAL STANDARD FOR BACITRACIN

Ref: 41-ISA_62_003

BACITRACIN ZINC CRS

CAS: 1405-89-6

BACITRACIN ZINC CRS

Formula: C₆₆H₁₀₃N₁₇O₁₆SZn

Colore e forma: White. Yellow. Powder.

Peso molecolare: 1488.101

Ref: 41-B0100000

Bacitracin Zinc

CAS: 1405-89-6

Antibiotics nesoi

Formula: C₆₆H₁₀₁N₁₇O₁₆SZn(BacitracinAZinc)C₆₅H₉₉N₁₇O₁₆SZn(BacitracinB₁B₂orB₃Zinc)

Colore e forma: White Tan Light Brown Powder

Peso molecolare: 2908.79 Bacitracin A Zinc

Ref: 45-1048007

Bacitracin (zinc)

CAS: 1405-89-6

Formula: C₆₆H₁₀₁N₁₇O₁₆SZn

Colore e forma: Solid

Peso molecolare: 1486.0574

Ref: IN-DA001CJR

Bacitracin zinc salt

CAS: 1405-89-6

Formula: C₆₆H₁₀₁N₁₇O₁₆SZn

Purezza: ≥ 65.0U/mg (dried basis)

Colore e forma: Off-white to light-yellow powder

Peso molecolare: 1486.07

Ref: 7W-GA1078

Bacitracin Zinc

CAS: 1405-89-6

Formula: C₆₆H₁₀₁N₁₇O₁₆S·Zn

Peso molecolare: 1420.70 65.38

Ref: 4Z-PB-073022

Bacitracin Zinc

CAS: 1405-89-6

Bacitracin Zinc is a dephosphorylated disruptor of C55-isoprene pyrophosphate that inhibits Tyr cleavage in Met-enkephalin with an IC50 of 10 μM.

Formula: C₆₆H₁₀₁N₁₇O₁₆SZn

Purezza: 63.98%

Colore e forma: Light-Colored Free-Flowing Powders

Peso molecolare: 1486.07

Ref: TM-T2208

Bacitracin Zinc (>80%)

Prodotto controllato

CAS: 1405-89-6

Applications Bacitracin is a peptide antibiotic effective against gram-postive bacteria. Bacitracin is an inhibitor of peptidoglycan synthesis. Bacitracin disrupts bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate. Bacitracin also strongly inhibits proline endopeptidase from human muscle.
References Ward, J.B. et al.: Biochem. J., 141, 227 (1974); Anastasi, A. et al.: Biochem. J., 290, 601 (1993); Daly, D.J. et al.: Biochem. Soc. Trans., 13, 1161 (1985); Weinberg, E.D. et al.: Antibiot. Ber., 90, (1967);

Formula: C₆₅H₉₉N₁₇O₁₆S·Zn

Purezza: >80%

Colore e forma: Light Yellow To Off-White

Peso molecolare: 1472.06

Ref: TR-B106505

Bacitracin zinc

CAS: 1405-89-6

Bacitracin zinc is a biocide that is used for the treatment of infectious diseases in animals. It has neurotrophic and polyvinyl pyrrolidone properties, which inhibit bacterial growth by preventing protein synthesis. Bacitracin zinc can be used to treat infections caused by bacteria that are resistant to penicillin, tetracycline, erythromycin, and other antibiotics. This drug can be formulated as a suspension or an emulsion in a polymeric matrix with undamaged polymer chains to provide stabilization against hydrolysis.

Formula: C₆₆H₁₀₁N₁₇O₁₆SZn

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 1,486.06 g/mol

Ref: 3D-FB37622